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Conserved domains on  [gi|2025113607|ref|NP_001381260|]
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schlafen-like protein 1 isoform 3 [Homo sapiens]

Protein Classification

ATP-binding protein( domain architecture ID 10515891)

ATP-binding protein similar to vertebrate schlafen family proteins, which are associated with embryonic lethality, meiotic drive, immune processes, and orthopoxvirus virulence

Gene Ontology:  GO:0005524

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
 221-305 9.09e-19

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


:

Pssm-ID: 461263  Cd Length: 116  Bit Score: 80.81  E-value: 9.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025113607 221 ETRNMEFKrgsgEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIrcSHRDEDRARLLVDSILQGFKPQIFPDA 300
Cdd:pfam04326   1 ESETLEFK----ESLGKSSKKKIAKTISAFANTEGGTIVIGVDDTGKIVGV--SDDEKDTEDLLKNQILDLIKPPIEVDI 74


                  ....*
gi 2025113607 301 YTLTF 305
Cdd:pfam04326  75 EEIEI 79
 
Name Accession Description Interval E-value
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
 221-305 9.09e-19

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


Pssm-ID: 461263  Cd Length: 116  Bit Score: 80.81  E-value: 9.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025113607 221 ETRNMEFKrgsgEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIrcSHRDEDRARLLVDSILQGFKPQIFPDA 300
Cdd:pfam04326   1 ESETLEFK----ESLGKSSKKKIAKTISAFANTEGGTIVIGVDDTGKIVGV--SDDEKDTEDLLKNQILDLIKPPIEVDI 74


                  ....*
gi 2025113607 301 YTLTF 305
Cdd:pfam04326  75 EEIEI 79
COG2865 COG2865
Predicted transcriptional regulator, contains HTH domain [Transcription];
221-305 8.36e-14

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 442112  Cd Length: 123  Bit Score: 67.22  E-value: 8.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025113607 221 ETRNMEFKRgsgeylSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIRCSHRDEDRarlLVDSILQGFKPQIFPDA 300
Cdd:COG2865    11 ESETLEFKE------SLNEPDEILKTVCAFANTEGGTLLIGVDDDGEIVGLDDPDKLLER---LENLIADNISPPIRPDV 81


                  ....*
gi 2025113607 301 YTLTF 305
Cdd:COG2865    82 EEVEI 86
 
Name Accession Description Interval E-value
AlbA_2 pfam04326
Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.
 221-305 9.09e-19

Putative DNA-binding domain; This family belongs to the AlbA clan of DNA-binding domains.


Pssm-ID: 461263  Cd Length: 116  Bit Score: 80.81  E-value: 9.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025113607 221 ETRNMEFKrgsgEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIrcSHRDEDRARLLVDSILQGFKPQIFPDA 300
Cdd:pfam04326   1 ESETLEFK----ESLGKSSKKKIAKTISAFANTEGGTIVIGVDDTGKIVGV--SDDEKDTEDLLKNQILDLIKPPIEVDI 74


                  ....*
gi 2025113607 301 YTLTF 305
Cdd:pfam04326  75 EEIEI 79
COG2865 COG2865
Predicted transcriptional regulator, contains HTH domain [Transcription];
221-305 8.36e-14

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 442112  Cd Length: 123  Bit Score: 67.22  E-value: 8.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025113607 221 ETRNMEFKRgsgeylSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIRCSHRDEDRarlLVDSILQGFKPQIFPDA 300
Cdd:COG2865    11 ESETLEFKE------SLNEPDEILKTVCAFANTEGGTLLIGVDDDGEIVGLDDPDKLLER---LENLIADNISPPIRPDV 81


                  ....*
gi 2025113607 301 YTLTF 305
Cdd:COG2865    82 EEVEI 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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