beta-galactosidase-1-like protein 2 isoform d precursor [Homo sapiens]
alpha-amylase family protein( domain architecture ID 1562432)
alpha-amylase family protein may catalyze the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides
List of domain hits
Name | Accession | Description | Interval | E-value | |||
AmyAc_family super family | cl38930 | Alpha amylase catalytic domain family; The Alpha-amylase family comprises the largest family ... |
53-149 | 3.93e-58 | |||
Alpha amylase catalytic domain family; The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; and C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost this catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase. The actual alignment was detected with superfamily member pfam01301: Pssm-ID: 453893 Cd Length: 316 Bit Score: 183.61 E-value: 3.93e-58
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Name | Accession | Description | Interval | E-value | |||
Glyco_hydro_35 | pfam01301 | Glycosyl hydrolases family 35; |
53-149 | 3.93e-58 | |||
Glycosyl hydrolases family 35; Pssm-ID: 396048 Cd Length: 316 Bit Score: 183.61 E-value: 3.93e-58
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GanA | COG1874 | Beta-galactosidase GanA [Carbohydrate transport and metabolism]; |
50-149 | 1.20e-25 | |||
Beta-galactosidase GanA [Carbohydrate transport and metabolism]; Pssm-ID: 224786 [Multi-domain] Cd Length: 673 Bit Score: 101.73 E-value: 1.20e-25
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PLN03059 | PLN03059 | beta-galactosidase; Provisional |
63-149 | 3.47e-23 | |||
beta-galactosidase; Provisional Pssm-ID: 166698 [Multi-domain] Cd Length: 840 Bit Score: 94.69 E-value: 3.47e-23
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Name | Accession | Description | Interval | E-value | |||
Glyco_hydro_35 | pfam01301 | Glycosyl hydrolases family 35; |
53-149 | 3.93e-58 | |||
Glycosyl hydrolases family 35; Pssm-ID: 396048 Cd Length: 316 Bit Score: 183.61 E-value: 3.93e-58
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GanA | COG1874 | Beta-galactosidase GanA [Carbohydrate transport and metabolism]; |
50-149 | 1.20e-25 | |||
Beta-galactosidase GanA [Carbohydrate transport and metabolism]; Pssm-ID: 224786 [Multi-domain] Cd Length: 673 Bit Score: 101.73 E-value: 1.20e-25
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PLN03059 | PLN03059 | beta-galactosidase; Provisional |
63-149 | 3.47e-23 | |||
beta-galactosidase; Provisional Pssm-ID: 166698 [Multi-domain] Cd Length: 840 Bit Score: 94.69 E-value: 3.47e-23
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Glyco_hydro_42 | pfam02449 | Beta-galactosidase; This group of beta-galactosidase enzymes belong to the glycosyl hydrolase ... |
71-136 | 8.77e-10 | |||
Beta-galactosidase; This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues. Pssm-ID: 396834 Cd Length: 376 Bit Score: 56.13 E-value: 8.77e-10
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Blast search parameters | ||||
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