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Conserved domains on  [gi|1579876392|ref|NP_001355688|]
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protein ARK2N isoform 2 [Mus musculus]

Protein Classification

ARKadia-like protein( domain architecture ID 142483)

ARKadia-like protein such as protein C18orf25, also known as ARKadia-like protein 1 (ARKL1), may function as an E3 ubiquitin-protein ligase

Gene Ontology:  GO:0061630

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNF111_N super family cl21149
E3 ubiquitin-protein ligase Arkadia N-terminus; This domain is found at the N-terminus of E3 ...
 88-212 2.65e-12

E3 ubiquitin-protein ligase Arkadia N-terminus; This domain is found at the N-terminus of E3 ubiquitin-protein ligase Arkadia.


The actual alignment was detected with superfamily member pfam15303:

Pssm-ID: 464629  Cd Length: 279  Bit Score: 66.11  E-value: 2.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1579876392  88 DSS-NHCMLSPSSSGHLADSDTLSSVEENEPSqaettVEGDTSGVSGATVGRKSRRSRSE---SETSTMAAKKNRQSSDK 163
Cdd:pfam15303 119 DSSfSDCASSPSSSLRFGDSDTLSSDEDREPS-----VRAHSPASLGATLGRTRGARSHKwprTEPEPVLMKRPCLHSRR 193

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1579876392 164 QNGRVTKVK-----GHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLT 212
Cdd:pfam15303 194 PPHRKRFVKtgsggGQRTQKQKERLLLQRKKREVIARRKYALLHSTSSSSEELS 247
 
Name Accession Description Interval E-value
RNF111_N pfam15303
E3 ubiquitin-protein ligase Arkadia N-terminus; This domain is found at the N-terminus of E3 ...
 88-212 2.65e-12

E3 ubiquitin-protein ligase Arkadia N-terminus; This domain is found at the N-terminus of E3 ubiquitin-protein ligase Arkadia.


Pssm-ID: 464629  Cd Length: 279  Bit Score: 66.11  E-value: 2.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1579876392  88 DSS-NHCMLSPSSSGHLADSDTLSSVEENEPSqaettVEGDTSGVSGATVGRKSRRSRSE---SETSTMAAKKNRQSSDK 163
Cdd:pfam15303 119 DSSfSDCASSPSSSLRFGDSDTLSSDEDREPS-----VRAHSPASLGATLGRTRGARSHKwprTEPEPVLMKRPCLHSRR 193

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1579876392 164 QNGRVTKVK-----GHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLT 212
Cdd:pfam15303 194 PPHRKRFVKtgsggGQRTQKQKERLLLQRKKREVIARRKYALLHSTSSSSEELS 247
 
Name Accession Description Interval E-value
RNF111_N pfam15303
E3 ubiquitin-protein ligase Arkadia N-terminus; This domain is found at the N-terminus of E3 ...
 88-212 2.65e-12

E3 ubiquitin-protein ligase Arkadia N-terminus; This domain is found at the N-terminus of E3 ubiquitin-protein ligase Arkadia.


Pssm-ID: 464629  Cd Length: 279  Bit Score: 66.11  E-value: 2.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1579876392  88 DSS-NHCMLSPSSSGHLADSDTLSSVEENEPSqaettVEGDTSGVSGATVGRKSRRSRSE---SETSTMAAKKNRQSSDK 163
Cdd:pfam15303 119 DSSfSDCASSPSSSLRFGDSDTLSSDEDREPS-----VRAHSPASLGATLGRTRGARSHKwprTEPEPVLMKRPCLHSRR 193

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1579876392 164 QNGRVTKVK-----GHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLT 212
Cdd:pfam15303 194 PPHRKRFVKtgsggGQRTQKQKERLLLQRKKREVIARRKYALLHSTSSSSEELS 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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