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Conserved domains on  [gi|556695484|ref|NP_001273347|]
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RNA binding protein fox-1 homolog 2 isoform 8 [Mus musculus]

Protein Classification

Fox-1_C domain-containing protein( domain architecture ID 10575148)

Fox-1_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Fox-1_C pfam12414
Calcitonin gene-related peptide regulator C terminal; This domain family is found in ...
158-255 6.61e-34

Calcitonin gene-related peptide regulator C terminal; This domain family is found in eukaryotes, and is typically between 69 and 99 amino acids in length. The family is found in association with pfam00076. This family is the C terminal of Fox-1, a protein involved in the regulation of calcitonin gene-related peptide to mediate the neuron-specific splicing pattern. Fox-1, with Fox-2, functions to repress exon 4 inclusion.


:

Pssm-ID: 432537  Cd Length: 96  Bit Score: 118.88  E-value: 6.61e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695484  158 VPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVR-AVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPatatAATAAA 236
Cdd:pfam12414   1 VPGFPYPTAATAAAAYRGAHLRGRGRTVYNTFRaAVPPPPIPAYGGVVYQDGFYGADLYGGYAAYRYAQP----AAAAAA 76
                          90       100
                  ....*....|....*....|
gi 556695484  237 AAAAAYSDGYGRVY-TADPY 255
Cdd:pfam12414  77 AAAAAYSDSYGRVYtTADPY 96
 
Name Accession Description Interval E-value
Fox-1_C pfam12414
Calcitonin gene-related peptide regulator C terminal; This domain family is found in ...
158-255 6.61e-34

Calcitonin gene-related peptide regulator C terminal; This domain family is found in eukaryotes, and is typically between 69 and 99 amino acids in length. The family is found in association with pfam00076. This family is the C terminal of Fox-1, a protein involved in the regulation of calcitonin gene-related peptide to mediate the neuron-specific splicing pattern. Fox-1, with Fox-2, functions to repress exon 4 inclusion.


Pssm-ID: 432537  Cd Length: 96  Bit Score: 118.88  E-value: 6.61e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695484  158 VPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVR-AVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPatatAATAAA 236
Cdd:pfam12414   1 VPGFPYPTAATAAAAYRGAHLRGRGRTVYNTFRaAVPPPPIPAYGGVVYQDGFYGADLYGGYAAYRYAQP----AAAAAA 76
                          90       100
                  ....*....|....*....|
gi 556695484  237 AAAAAYSDGYGRVY-TADPY 255
Cdd:pfam12414  77 AAAAAYSDSYGRVYtTADPY 96
 
Name Accession Description Interval E-value
Fox-1_C pfam12414
Calcitonin gene-related peptide regulator C terminal; This domain family is found in ...
158-255 6.61e-34

Calcitonin gene-related peptide regulator C terminal; This domain family is found in eukaryotes, and is typically between 69 and 99 amino acids in length. The family is found in association with pfam00076. This family is the C terminal of Fox-1, a protein involved in the regulation of calcitonin gene-related peptide to mediate the neuron-specific splicing pattern. Fox-1, with Fox-2, functions to repress exon 4 inclusion.


Pssm-ID: 432537  Cd Length: 96  Bit Score: 118.88  E-value: 6.61e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 556695484  158 VPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVR-AVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPatatAATAAA 236
Cdd:pfam12414   1 VPGFPYPTAATAAAAYRGAHLRGRGRTVYNTFRaAVPPPPIPAYGGVVYQDGFYGADLYGGYAAYRYAQP----AAAAAA 76
                          90       100
                  ....*....|....*....|
gi 556695484  237 AAAAAYSDGYGRVY-TADPY 255
Cdd:pfam12414  77 AAAAAYSDSYGRVYtTADPY 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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