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Conserved domains on  [gi|197333730|ref|NP_001127956|]
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mitochondrial import receptor subunit TOM5 homolog isoform 3 [Homo sapiens]

Protein Classification

mitochondrial import receptor subunit TOM5( domain architecture ID 10566320)

mitochondrial import receptor subunit TOM5 is a component of the TOM (translocase of outer membrane) receptor complex that is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tom5 pfam10642
Mitochondrial import receptor subunit or translocase; This protein family is very short and is ...
 1-41 1.71e-08

Mitochondrial import receptor subunit or translocase; This protein family is very short and is only found in yeasts. Tom5 is one of three very small translocases of the mitochondrial outer membrane. Tom5 links mitochondrial preprotein receptors to the general import pore. Deletion of the C-terminal transmembrane domain of Tom5 interfered with phosphatidylserine (PS) transfer to mitochondria and disrupted mitochondrial function.


:

Pssm-ID: 431410  Cd Length: 47  Bit Score: 46.02  E-value: 1.71e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 197333730   1 MFrieGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVS 41
Cdd:pfam10642  1 MF---GGGPPQPSEEEIKAQEAEARATVKNFAAAAALLYLS 38
 
Name Accession Description Interval E-value
Tom5 pfam10642
Mitochondrial import receptor subunit or translocase; This protein family is very short and is ...
 1-41 1.71e-08

Mitochondrial import receptor subunit or translocase; This protein family is very short and is only found in yeasts. Tom5 is one of three very small translocases of the mitochondrial outer membrane. Tom5 links mitochondrial preprotein receptors to the general import pore. Deletion of the C-terminal transmembrane domain of Tom5 interfered with phosphatidylserine (PS) transfer to mitochondria and disrupted mitochondrial function.


Pssm-ID: 431410  Cd Length: 47  Bit Score: 46.02  E-value: 1.71e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 197333730   1 MFrieGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVS 41
Cdd:pfam10642  1 MF---GGGPPQPSEEEIKAQEAEARATVKNFAAAAALLYLS 38
 
Name Accession Description Interval E-value
Tom5 pfam10642
Mitochondrial import receptor subunit or translocase; This protein family is very short and is ...
 1-41 1.71e-08

Mitochondrial import receptor subunit or translocase; This protein family is very short and is only found in yeasts. Tom5 is one of three very small translocases of the mitochondrial outer membrane. Tom5 links mitochondrial preprotein receptors to the general import pore. Deletion of the C-terminal transmembrane domain of Tom5 interfered with phosphatidylserine (PS) transfer to mitochondria and disrupted mitochondrial function.


Pssm-ID: 431410  Cd Length: 47  Bit Score: 46.02  E-value: 1.71e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 197333730   1 MFrieGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVS 41
Cdd:pfam10642  1 MF---GGGPPQPSEEEIKAQEAEARATVKNFAAAAALLYLS 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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