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Conserved domains on  [gi|149408119|ref|NP_001092287|]
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INO80 complex subunit C isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YL1_C super family cl02154
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 103-223 4.75e-20

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


The actual alignment was detected with superfamily member COG5195:

Pssm-ID: 470478 [Multi-domain]  Cd Length: 118  Bit Score: 81.96  E-value: 4.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149408119 103 SEFSTGPVEKAAKPLpFKDPNFVhsghggavagKKNRTWKNLKQILASErALPWQLNDPNYFSIDAPPSFKPAKKYSDVS 182
Cdd:COG5195    5 NNNDGGDMKLLKRPW-FKKSTYK----------GKNRRFKTLRQLIPRL-TIENESSKHRYLSIEAPPSVKPRMKYCDVT 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 149408119 183 GLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKA 223
Cdd:COG5195   73 GLPAPYTCPNTGLRYHNSEIYKLICELPSGRDQEYLKLREF 113
 
Name Accession Description Interval E-value
COG5195 COG5195
Uncharacterized conserved protein [Function unknown];
103-223 4.75e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227522 [Multi-domain]  Cd Length: 118  Bit Score: 81.96  E-value: 4.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149408119 103 SEFSTGPVEKAAKPLpFKDPNFVhsghggavagKKNRTWKNLKQILASErALPWQLNDPNYFSIDAPPSFKPAKKYSDVS 182
Cdd:COG5195    5 NNNDGGDMKLLKRPW-FKKSTYK----------GKNRRFKTLRQLIPRL-TIENESSKHRYLSIEAPPSVKPRMKYCDVT 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 149408119 183 GLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKA 223
Cdd:COG5195   73 GLPAPYTCPNTGLRYHNSEIYKLICELPSGRDQEYLKLREF 113
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 177-206 6.89e-09

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 49.82  E-value: 6.89e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 149408119   177 KYSDVSGLLANYTDPQSKLRFSTIEEFSYI 206
Cdd:smart00993   1 KYCDITGLPARYRDPKTGLRYANAEAYKVI 30
YL1_C pfam08265
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 178-206 1.38e-07

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 462412  Cd Length: 29  Bit Score: 46.21  E-value: 1.38e-07
                          10        20
                  ....*....|....*....|....*....
gi 149408119  178 YSDVSGLLANYTDPQSKLRFSTIEEFSYI 206
Cdd:pfam08265   1 YCDITGLPAKYRDPKTGLPYANVEAYKVI 29
 
Name Accession Description Interval E-value
COG5195 COG5195
Uncharacterized conserved protein [Function unknown];
103-223 4.75e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227522 [Multi-domain]  Cd Length: 118  Bit Score: 81.96  E-value: 4.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149408119 103 SEFSTGPVEKAAKPLpFKDPNFVhsghggavagKKNRTWKNLKQILASErALPWQLNDPNYFSIDAPPSFKPAKKYSDVS 182
Cdd:COG5195    5 NNNDGGDMKLLKRPW-FKKSTYK----------GKNRRFKTLRQLIPRL-TIENESSKHRYLSIEAPPSVKPRMKYCDVT 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 149408119 183 GLLANYTDPQSKLRFSTIEEFSYIRRLPSDVVTGYLALRKA 223
Cdd:COG5195   73 GLPAPYTCPNTGLRYHNSEIYKLICELPSGRDQEYLKLREF 113
YL1_C smart00993
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 177-206 6.89e-09

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 198061 [Multi-domain]  Cd Length: 30  Bit Score: 49.82  E-value: 6.89e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 149408119   177 KYSDVSGLLANYTDPQSKLRFSTIEEFSYI 206
Cdd:smart00993   1 KYCDITGLPARYRDPKTGLRYANAEAYKVI 30
YL1_C pfam08265
YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. ...
 178-206 1.38e-07

YL1 nuclear protein C-terminal domain; This domain is found in proteins of the YL1 family. These proteins have been shown to be DNA-binding and may be a transcription factor. This domain is found in proteins that are not YL1 proteins.


Pssm-ID: 462412  Cd Length: 29  Bit Score: 46.21  E-value: 1.38e-07
                          10        20
                  ....*....|....*....|....*....
gi 149408119  178 YSDVSGLLANYTDPQSKLRFSTIEEFSYI 206
Cdd:pfam08265   1 YCDITGLPAKYRDPKTGLPYANVEAYKVI 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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