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Conserved domains on  [gi|115533134|ref|NP_001041089|]
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DM domain-containing protein mab-23 [Caenorhabditis elegans]

Protein Classification

DM domain-containing protein( domain architecture ID 2554)

DM (doublesex- and mab-3) domain-containing protein may dimerize and bind palindromic DNA; similar to Danio rerio doublesex- and mab-3-related transcription factor 3b

Gene Ontology:  GO:0043565|GO:0006355
PubMed:  22310892

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DM super family cl02557
DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single ...
6-55 6.62e-13

DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. The dsx DM domain has been shown to dimerize and bind palindromic DNA.


The actual alignment was detected with superfamily member smart00301:

Pssm-ID: 445828  Cd Length: 54  Bit Score: 60.07  E-value: 6.62e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 115533134     6 YMCQLCANHGIFNqPKKGHKQKCPYRTCPCSLCALNTKRRALDQIERQLK 55
Cdd:smart00301   3 PYCQKCENHGVKV-PLKGHKPECPFRDCECEKCTLVEKRRALMALQIKLK 51
 
Name Accession Description Interval E-value
DM smart00301
Doublesex DNA-binding motif;
6-55 6.62e-13

Doublesex DNA-binding motif;


Pssm-ID: 214606  Cd Length: 54  Bit Score: 60.07  E-value: 6.62e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 115533134     6 YMCQLCANHGIFNqPKKGHKQKCPYRTCPCSLCALNTKRRALDQIERQLK 55
Cdd:smart00301   3 PYCQKCENHGVKV-PLKGHKPECPFRDCECEKCTLVEKRRALMALQIKLK 51
DM pfam00751
DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single ...
5-45 1.53e-12

DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. The dsx DM domain has been shown to dimerize and bind palindromic DNA.


Pssm-ID: 425850  Cd Length: 47  Bit Score: 58.82  E-value: 1.53e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 115533134    5 QYMCQLCANHGIfNQPKKGHKQKCPYRTCPCSLCALNTKRR 45
Cdd:pfam00751   2 SPKCARCRNHGV-IVPLKGHKRYCPYRDCTCPKCLLVAERQ 41
 
Name Accession Description Interval E-value
DM smart00301
Doublesex DNA-binding motif;
6-55 6.62e-13

Doublesex DNA-binding motif;


Pssm-ID: 214606  Cd Length: 54  Bit Score: 60.07  E-value: 6.62e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 115533134     6 YMCQLCANHGIFNqPKKGHKQKCPYRTCPCSLCALNTKRRALDQIERQLK 55
Cdd:smart00301   3 PYCQKCENHGVKV-PLKGHKPECPFRDCECEKCTLVEKRRALMALQIKLK 51
DM pfam00751
DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single ...
5-45 1.53e-12

DM DNA binding domain; The DM domain is named after dsx and mab-3. dsx contains a single amino-terminal DM domain, whereas mab-3 contains two amino-terminal domains. The DM domain has a pattern of conserved zinc chelating residues C2H2C4. The dsx DM domain has been shown to dimerize and bind palindromic DNA.


Pssm-ID: 425850  Cd Length: 47  Bit Score: 58.82  E-value: 1.53e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 115533134    5 QYMCQLCANHGIfNQPKKGHKQKCPYRTCPCSLCALNTKRR 45
Cdd:pfam00751   2 SPKCARCRNHGV-IVPLKGHKRYCPYRDCTCPKCLLVAERQ 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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