EGF-like repeat and discoidin I-like domain-containing protein 3 isoform a precursor [Mus musculus]
EGF_CA and FA58C domain-containing protein( domain architecture ID 10439819)
EGF_CA and FA58C domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||
FA58C | cd00057 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
160-313 | 3.86e-63 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. : Pssm-ID: 238014 [Multi-domain] Cd Length: 143 Bit Score: 201.43 E-value: 3.86e-63
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FA58C | cd00057 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
321-475 | 1.29e-52 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. : Pssm-ID: 238014 [Multi-domain] Cd Length: 143 Bit Score: 174.08 E-value: 1.29e-52
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
119-155 | 3.00e-09 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. : Pssm-ID: 238011 Cd Length: 38 Bit Score: 52.25 E-value: 3.00e-09
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
26-58 | 2.73e-06 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. : Pssm-ID: 394967 Cd Length: 31 Bit Score: 43.91 E-value: 2.73e-06
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
80-117 | 1.97e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. : Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.47 E-value: 1.97e-05
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Name | Accession | Description | Interval | E-value | |||
FA58C | cd00057 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
160-313 | 3.86e-63 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 238014 [Multi-domain] Cd Length: 143 Bit Score: 201.43 E-value: 3.86e-63
|
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FA58C | cd00057 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
321-475 | 1.29e-52 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 238014 [Multi-domain] Cd Length: 143 Bit Score: 174.08 E-value: 1.29e-52
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FA58C | smart00231 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
157-314 | 1.16e-45 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 214572 Cd Length: 139 Bit Score: 155.74 E-value: 1.16e-45
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FA58C | smart00231 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
318-476 | 4.53e-38 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 214572 Cd Length: 139 Bit Score: 135.71 E-value: 4.53e-38
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F5_F8_type_C | pfam00754 | F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. |
334-473 | 3.96e-36 | |||
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. Pssm-ID: 459925 [Multi-domain] Cd Length: 127 Bit Score: 129.87 E-value: 3.96e-36
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F5_F8_type_C | pfam00754 | F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. |
173-311 | 6.57e-32 | |||
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. Pssm-ID: 459925 [Multi-domain] Cd Length: 127 Bit Score: 118.70 E-value: 6.57e-32
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
119-155 | 3.00e-09 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 52.25 E-value: 3.00e-09
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
119-155 | 5.85e-08 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 48.78 E-value: 5.85e-08
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
26-58 | 2.73e-06 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. Pssm-ID: 394967 Cd Length: 31 Bit Score: 43.91 E-value: 2.73e-06
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
28-59 | 9.53e-06 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 42.24 E-value: 9.53e-06
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
80-117 | 1.97e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.47 E-value: 1.97e-05
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
78-115 | 2.19e-04 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. Pssm-ID: 394967 Cd Length: 31 Bit Score: 38.52 E-value: 2.19e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
80-117 | 2.20e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 38.77 E-value: 2.20e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
28-59 | 4.69e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.61 E-value: 4.69e-04
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Name | Accession | Description | Interval | E-value | |||
FA58C | cd00057 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
160-313 | 3.86e-63 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 238014 [Multi-domain] Cd Length: 143 Bit Score: 201.43 E-value: 3.86e-63
|
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FA58C | cd00057 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
321-475 | 1.29e-52 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 238014 [Multi-domain] Cd Length: 143 Bit Score: 174.08 E-value: 1.29e-52
|
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FA58C | smart00231 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
157-314 | 1.16e-45 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 214572 Cd Length: 139 Bit Score: 155.74 E-value: 1.16e-45
|
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FA58C | smart00231 | Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached ... |
318-476 | 4.53e-38 | |||
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. Pssm-ID: 214572 Cd Length: 139 Bit Score: 135.71 E-value: 4.53e-38
|
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F5_F8_type_C | pfam00754 | F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. |
334-473 | 3.96e-36 | |||
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. Pssm-ID: 459925 [Multi-domain] Cd Length: 127 Bit Score: 129.87 E-value: 3.96e-36
|
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F5_F8_type_C | pfam00754 | F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. |
173-311 | 6.57e-32 | |||
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. Pssm-ID: 459925 [Multi-domain] Cd Length: 127 Bit Score: 118.70 E-value: 6.57e-32
|
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
119-155 | 3.00e-09 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 52.25 E-value: 3.00e-09
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
119-155 | 5.85e-08 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 48.78 E-value: 5.85e-08
|
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
26-58 | 2.73e-06 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. Pssm-ID: 394967 Cd Length: 31 Bit Score: 43.91 E-value: 2.73e-06
|
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
28-59 | 9.53e-06 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 42.24 E-value: 9.53e-06
|
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
80-117 | 1.97e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.47 E-value: 1.97e-05
|
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
78-115 | 2.19e-04 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. Pssm-ID: 394967 Cd Length: 31 Bit Score: 38.52 E-value: 2.19e-04
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
80-117 | 2.20e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 38.77 E-value: 2.20e-04
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EGF | cd00053 | Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ... |
122-155 | 4.19e-04 | |||
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium. Pssm-ID: 238010 Cd Length: 36 Bit Score: 37.84 E-value: 4.19e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
28-59 | 4.69e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.61 E-value: 4.69e-04
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EGF | cd00053 | Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ... |
27-58 | 1.55e-03 | |||
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium. Pssm-ID: 238010 Cd Length: 36 Bit Score: 36.30 E-value: 1.55e-03
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EGF | cd00053 | Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ... |
80-117 | 2.23e-03 | |||
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium. Pssm-ID: 238010 Cd Length: 36 Bit Score: 35.53 E-value: 2.23e-03
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Blast search parameters | ||||
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