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Conserved domains on  [gi|57165364|ref|NP_001008901|]
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gametocyte-specific factor 1-like isoform 2 [Homo sapiens]

Protein Classification

CHHC zinc finger protein( domain architecture ID 10526107)

CHHC zinc finger protein similar to human U11/U12 small nuclear ribonucleoprotein 48 kDa protein that may be involved in U12-type 5' splice site recognition; the CHHC region interacts with the 5' splice site of the U12-type intron

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-U11-48K pfam05253
U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating ...
 6-30 4.50e-07

U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating residues in a CHHC pattern. This domain is predicted to have an RNA-binding function.


:

Pssm-ID: 461603  Cd Length: 25  Bit Score: 42.81  E-value: 4.50e-07
                          10        20
                  ....*....|....*....|....*
gi 57165364     6 FEICPYDPHHRIPLSRFQYHLASCR 30
Cdd:pfam05253   1 LVPCPYNPSHRVPESRLEKHLKKCP 25
zf-U11-48K pfam05253
U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating ...
 40-63 1.71e-04

U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating residues in a CHHC pattern. This domain is predicted to have an RNA-binding function.


:

Pssm-ID: 461603  Cd Length: 25  Bit Score: 36.27  E-value: 1.71e-04
                          10        20
                  ....*....|....*....|....
gi 57165364    40 MATCKYNACHVVPIKNLEEHEAVC 63
Cdd:pfam05253   1 LVPCPYNPSHRVPESRLEKHLKKC 24
 
Name Accession Description Interval E-value
zf-U11-48K pfam05253
U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating ...
 6-30 4.50e-07

U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating residues in a CHHC pattern. This domain is predicted to have an RNA-binding function.


Pssm-ID: 461603  Cd Length: 25  Bit Score: 42.81  E-value: 4.50e-07
                          10        20
                  ....*....|....*....|....*
gi 57165364     6 FEICPYDPHHRIPLSRFQYHLASCR 30
Cdd:pfam05253   1 LVPCPYNPSHRVPESRLEKHLKKCP 25
zf-U11-48K pfam05253
U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating ...
 40-63 1.71e-04

U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating residues in a CHHC pattern. This domain is predicted to have an RNA-binding function.


Pssm-ID: 461603  Cd Length: 25  Bit Score: 36.27  E-value: 1.71e-04
                          10        20
                  ....*....|....*....|....
gi 57165364    40 MATCKYNACHVVPIKNLEEHEAVC 63
Cdd:pfam05253   1 LVPCPYNPSHRVPESRLEKHLKKC 24
 
Name Accession Description Interval E-value
zf-U11-48K pfam05253
U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating ...
 6-30 4.50e-07

U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating residues in a CHHC pattern. This domain is predicted to have an RNA-binding function.


Pssm-ID: 461603  Cd Length: 25  Bit Score: 42.81  E-value: 4.50e-07
                          10        20
                  ....*....|....*....|....*
gi 57165364     6 FEICPYDPHHRIPLSRFQYHLASCR 30
Cdd:pfam05253   1 LVPCPYNPSHRVPESRLEKHLKKCP 25
zf-U11-48K pfam05253
U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating ...
 40-63 1.71e-04

U11-48K-like CHHC zinc finger; This zinc binding domain has four conserved zinc chelating residues in a CHHC pattern. This domain is predicted to have an RNA-binding function.


Pssm-ID: 461603  Cd Length: 25  Bit Score: 36.27  E-value: 1.71e-04
                          10        20
                  ....*....|....*....|....
gi 57165364    40 MATCKYNACHVVPIKNLEEHEAVC 63
Cdd:pfam05253   1 LVPCPYNPSHRVPESRLEKHLKKC 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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