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Conserved domains on  [lcl|seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59]
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WP_017220614.1 NCBI__GCF_000276805.1:WP_017220614.1

Protein Classification

phosphate acetyltransferase( domain architecture ID 11481340)

phosphate acetyltransferase catalyzes the reversible interconversion of acetyl-CoA and acetyl phosphate and is involved in acetate metabolism

EC:  2.3.1.8
Gene Ontology:  GO:0006083|GO:0045733|GO:0019413|GO:0005829|GO:0008959|GO:0070689|GO:0008270|GO:0019427
PubMed:  12980995

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05632 PRK05632
phosphate acetyltransferase; Reviewed
 1-704 0e+00

phosphate acetyltransferase; Reviewed


:

Pssm-ID: 235537 [Multi-domain]  Cd Length: 684  Bit Score: 1228.09  E-value: 0e+00
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59   1 MLIPVGVGVGVTSVSLGMVRAFERNGLNVNFFKPVAQPrqgekgpelsteiirqgtnaspatPFTLSHAEKLIGAGKTDV 80
Cdd:PRK05632                                    6 YLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLASGQLDE 61

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  81 LLEDIVERFESHMVDAEIVVVEGLVPTSKQPFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACSNFGGSKNKN 160
Cdd:PRK05632                                   62 LLEEIVARYHALAKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSFGGAKNAN 141

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 161 IIGCVINKVGAPLDEAGRSRPDLAEMFEANAgnaSHNLEVLQVFGKSPMPILGCIPWSAELIAPRAKDLAKHLGAEILNE 240
Cdd:PRK05632                                  142 ILGVIINKLNAPVDEQGRTRPDLSEIFDDSS---KANVDPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAKHLGATVLNE 218

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 241 GDIEERRLVGITFCARSIPNMLEHFRPGGLLVTSGDRADVIVAACLAAMNGVKIGALLLTGDVRPDASVLKLCQQAMATG 320
Cdd:PRK05632                                  219 GDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAKLCEGAFETG 298

                                                         330       340       350       360       370       380       390       400
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 321 LPIMLTPTNTWQTALTLQNFNLDIPADDKQRIEAVQEYIASHIDKQ-WIESLTVGTQRTRRLSPPAFRYQLTELARQAKK 399
Cdd:PRK05632                                  299 LPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQLTERARAAKK 378

                                                         410       420       430       440       450       460       470       480
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 400 RVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDGVEIIDPVTCLEKYVAPMVELRKAKGLTEVV 479
Cdd:PRK05632                                  379 RIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELRKHKGMTEEV 458

                                                         490       500       510       520       530       540       550       560
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 480 AREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDASQ 559
Cdd:PRK05632                                  459 AREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAVNPDPTAEQ 538

                                                         570       580       590       600       610       620       630       640
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 560 LADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNSPV 639
Cdd:PRK05632                                  539 LAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVARSKAPNSPV 618

                                                         650       660       670       680       690       700
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 640 AGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQA 704
Cdd:PRK05632                                  619 AGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQA 683
 
Name Accession Description Interval E-value
PRK05632 PRK05632
phosphate acetyltransferase; Reviewed
 1-704 0e+00

phosphate acetyltransferase; Reviewed


Pssm-ID: 235537 [Multi-domain]  Cd Length: 684  Bit Score: 1228.09  E-value: 0e+00
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59   1 MLIPVGVGVGVTSVSLGMVRAFERNGLNVNFFKPVAQPrqgekgpelsteiirqgtnaspatPFTLSHAEKLIGAGKTDV 80
Cdd:PRK05632                                    6 YLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLASGQLDE 61

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  81 LLEDIVERFESHMVDAEIVVVEGLVPTSKQPFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACSNFGGSKNKN 160
Cdd:PRK05632                                   62 LLEEIVARYHALAKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSFGGAKNAN 141

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 161 IIGCVINKVGAPLDEAGRSRPDLAEMFEANAgnaSHNLEVLQVFGKSPMPILGCIPWSAELIAPRAKDLAKHLGAEILNE 240
Cdd:PRK05632                                  142 ILGVIINKLNAPVDEQGRTRPDLSEIFDDSS---KANVDPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAKHLGATVLNE 218

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 241 GDIEERRLVGITFCARSIPNMLEHFRPGGLLVTSGDRADVIVAACLAAMNGVKIGALLLTGDVRPDASVLKLCQQAMATG 320
Cdd:PRK05632                                  219 GDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAKLCEGAFETG 298

                                                         330       340       350       360       370       380       390       400
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 321 LPIMLTPTNTWQTALTLQNFNLDIPADDKQRIEAVQEYIASHIDKQ-WIESLTVGTQRTRRLSPPAFRYQLTELARQAKK 399
Cdd:PRK05632                                  299 LPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQLTERARAAKK 378

                                                         410       420       430       440       450       460       470       480
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 400 RVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDGVEIIDPVTCLEKYVAPMVELRKAKGLTEVV 479
Cdd:PRK05632                                  379 RIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELRKHKGMTEEV 458

                                                         490       500       510       520       530       540       550       560
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 480 AREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDASQ 559
Cdd:PRK05632                                  459 AREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAVNPDPTAEQ 538

                                                         570       580       590       600       610       620       630       640
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 560 LADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNSPV 639
Cdd:PRK05632                                  539 LAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVARSKAPNSPV 618

                                                         650       660       670       680       690       700
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 640 AGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQA 704
Cdd:PRK05632                                  619 AGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQA 683
PtaN COG0857
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
12-706 0e+00

BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];


Pssm-ID: 440618 [Multi-domain]  Cd Length: 697  Bit Score: 818.30  E-value: 0e+00
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  12 TSVSLGMVRAFERNGLNVNFFKPVAQPRQGEKGPELSTEIIRQGTNAS----PATPFTLSHAEKLIGAGKTDVLLEDIVE 87
Cdd:COG0857                                    17 TSVALGLARALQRKGLRVGYFKPIGQSLVGGGERDEDVELIREHLGLDlpyeDASPVTLDEVETLLAEGDPDELLERIVE 96

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  88 RFESHMVDAEIVVVEGLVPTSKQ-PFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACSNFGGsKNKNIIGCVI 166
Cdd:COG0857                                    97 RYEALAAECDVVLVEGSDPTGVGsPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLLAADEFRG-EGARVLGVII 175

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 167 NKVGAPLDEAGRSrpdlaemfeanagnashnlEVLQVFGKSPMPILGCIPWSAELIAPRAKDLAKHLGAEILNEGDIEER 246
Cdd:COG0857                                   176 NRVPPEKLEEVRE-------------------ALRPFLEGSGIPVLGVIPENPELAAPTVRDLAEALGAEVLNGGELLDR 236

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 247 RLVGITFCARSIPNMLEHFRPGGLLVTSGDRADVIVAACLAAMNGV-KIGALLLTGDVRPDASVLKLCQQAMATgLPIML 325
Cdd:COG0857                                   237 RVESVVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGTpSIAGLILTGGLPPDPAVLRLAEGLGQT-LPILS 315

                                                         330       340       350       360       370       380       390       400
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 326 TPTNTWQTALTLQNFNLDIPADDKQRIEAVQEYIASHIDKQWIESLtVGTQRTRrLSPPAFRYQLTELARQAKKRVVLPE 405
Cdd:COG0857                                   316 VELDTYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSR-LGLPRSR-LSPPAFFYYLLERAARAAKRIVLPE 393

                                                         410       420       430       440       450       460       470       480
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 406 GEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDGVEIIDPVTCLEKYVAPMVELRKAKGLTEVVAREQLQ 485
Cdd:COG0857                                   394 GGEDRRILAAAICLLRRIAACVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAAEVYLRRRKKKGVTVAAAQLE 473

                                                         490       500       510       520       530       540       550       560
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 486 DSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDASQLADIAI 565
Cdd:COG0857                                   474 DDVVLYTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVVVGDCACAPNPPPEELALAAI 553

                                                         570       580       590       600       610       620       630       640
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 566 QSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNSPVAGKATV 645
Cdd:COG0857                                   554 ISSSSAAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAAAADVVVAKAKPSPVAGAAAA 633

                                                         650       660       670       680       690       700
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|.
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 646 FVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAKQ 706
Cdd:COG0857                                   634 FVFPFLDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQQ 694
pta TIGR00651
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ...
 401-701 3.87e-166

phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]


Pssm-ID: 273196 [Multi-domain]  Cd Length: 303  Bit Score: 479.24  E-value: 3.87e-166
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 401 VVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDgVEIIDPVTC--LEKYVAPMVELRKAKGLTEV 478
Cdd:TIGR00651                                   1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKAAGCNLDLGH-VVIIDPDVSpdRESYAERYVELRKHKGMTEA 79

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 479 VAREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDAS 558
Cdd:TIGR00651                                  80 QARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNAE 159

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 559 QLADIAIQSADSAKAFG-IDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNS 637
Cdd:TIGR00651                                 160 QLAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPNS 239

                                                         250       260       270       280       290       300
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 638 PVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 701
Cdd:TIGR00651                                 240 PVAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAITA 303
PTA_PTB pfam01515
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ...
 386-701 4.87e-158

Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.


Pssm-ID: 396207 [Multi-domain]  Cd Length: 318  Bit Score: 459.09  E-value: 4.87e-158
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 386 FRYQLTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILsDGVEIIDPVT--CLEKYV 463
Cdd:pfam01515                                   1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDL-DGIEIVDPETspRLEEYA 79

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 464 APMVELRKAKGLTEVVAREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQV 543
Cdd:pfam01515                                  80 DFYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGL 159

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 544 LVYGDCAINPDPDASQLADIAIQSADSAKAFG-IDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYD 622
Cdd:pfam01515                                 160 LFFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFD 239

                                                         250       260       270       280       290       300       310
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 623 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 701
Cdd:pfam01515                                 240 AALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAITA 318
DTBS cd03109
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ...
 12-188 7.53e-20

dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.


Pssm-ID: 349763 [Multi-domain]  Cd Length: 189  Bit Score: 88.01  E-value: 7.53e-20
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  12 TSVSLGMVRAFERNGLNVNFFKPVAQprQGEKGPELSTEIIRQGTNASPA----TPFTLSH--AEKLIGAGK-TDVLLED 84
Cdd:cd03109                                    15 TVVSAGLARALRKKGIKVGYLKPVQT--GCPGLEDSDAELLRKLAGLLLDleliNPYRFEAplSPHLAAELEgRDIDLEE 92

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  85 IVERFESHMVDAEIVVVEGLVPTSKQPFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACsnfggSKNKNIIGC 164
Cdd:cd03109                                    93 IVRALEELAKSYDVVLVEGAGGLLVPLTEGYLNADLARALGLPVILVARGGLGTINHTLLTLEALK-----SRGLDVAGV 167

                                                         170       180
                                                  ....*....|....*....|....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 165 VINKVgaplDEAGRSRPDLAEMFE 188
Cdd:cd03109                                   168 VLNGI----PPEPEAEADNAETLK 187
 
Name Accession Description Interval E-value
PRK05632 PRK05632
phosphate acetyltransferase; Reviewed
 1-704 0e+00

phosphate acetyltransferase; Reviewed


Pssm-ID: 235537 [Multi-domain]  Cd Length: 684  Bit Score: 1228.09  E-value: 0e+00
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59   1 MLIPVGVGVGVTSVSLGMVRAFERNGLNVNFFKPVAQPrqgekgpelsteiirqgtnaspatPFTLSHAEKLIGAGKTDV 80
Cdd:PRK05632                                    6 YLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP------------------------PLTMSEVEALLASGQLDE 61

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  81 LLEDIVERFESHMVDAEIVVVEGLVPTSKQPFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACSNFGGSKNKN 160
Cdd:PRK05632                                   62 LLEEIVARYHALAKDCDVVLVEGLDPTRKHPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAASSFGGAKNAN 141

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 161 IIGCVINKVGAPLDEAGRSRPDLAEMFEANAgnaSHNLEVLQVFGKSPMPILGCIPWSAELIAPRAKDLAKHLGAEILNE 240
Cdd:PRK05632                                  142 ILGVIINKLNAPVDEQGRTRPDLSEIFDDSS---KANVDPSKLFASSPLPLLGVVPWSPDLIAPRVIDIAKHLGATVLNE 218

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 241 GDIEERRLVGITFCARSIPNMLEHFRPGGLLVTSGDRADVIVAACLAAMNGVKIGALLLTGDVRPDASVLKLCQQAMATG 320
Cdd:PRK05632                                  219 GDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNGPPIAGLLLTGGYEPDPRIAKLCEGAFETG 298

                                                         330       340       350       360       370       380       390       400
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 321 LPIMLTPTNTWQTALTLQNFNLDIPADDKQRIEAVQEYIASHIDKQ-WIESLTVGTQRTRRLSPPAFRYQLTELARQAKK 399
Cdd:PRK05632                                  299 LPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDeLLERLTATSERSRRLSPPAFRYQLTERARAAKK 378

                                                         410       420       430       440       450       460       470       480
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 400 RVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDGVEIIDPVTCLEKYVAPMVELRKAKGLTEVV 479
Cdd:PRK05632                                  379 RIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLPAGIEIIDPSEVRERYVAPLVELRKHKGMTEEV 458

                                                         490       500       510       520       530       540       550       560
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 480 AREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDASQ 559
Cdd:PRK05632                                  459 AREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAVNPDPTAEQ 538

                                                         570       580       590       600       610       620       630       640
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 560 LADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNSPV 639
Cdd:PRK05632                                  539 LAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSVARSKAPNSPV 618

                                                         650       660       670       680       690       700
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 640 AGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQA 704
Cdd:PRK05632                                  619 AGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQA 683
PtaN COG0857
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
12-706 0e+00

BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];


Pssm-ID: 440618 [Multi-domain]  Cd Length: 697  Bit Score: 818.30  E-value: 0e+00
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  12 TSVSLGMVRAFERNGLNVNFFKPVAQPRQGEKGPELSTEIIRQGTNAS----PATPFTLSHAEKLIGAGKTDVLLEDIVE 87
Cdd:COG0857                                    17 TSVALGLARALQRKGLRVGYFKPIGQSLVGGGERDEDVELIREHLGLDlpyeDASPVTLDEVETLLAEGDPDELLERIVE 96

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  88 RFESHMVDAEIVVVEGLVPTSKQ-PFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACSNFGGsKNKNIIGCVI 166
Cdd:COG0857                                    97 RYEALAAECDVVLVEGSDPTGVGsPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLLAADEFRG-EGARVLGVII 175

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 167 NKVGAPLDEAGRSrpdlaemfeanagnashnlEVLQVFGKSPMPILGCIPWSAELIAPRAKDLAKHLGAEILNEGDIEER 246
Cdd:COG0857                                   176 NRVPPEKLEEVRE-------------------ALRPFLEGSGIPVLGVIPENPELAAPTVRDLAEALGAEVLNGGELLDR 236

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 247 RLVGITFCARSIPNMLEHFRPGGLLVTSGDRADVIVAACLAAMNGV-KIGALLLTGDVRPDASVLKLCQQAMATgLPIML 325
Cdd:COG0857                                   237 RVESVVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGTpSIAGLILTGGLPPDPAVLRLAEGLGQT-LPILS 315

                                                         330       340       350       360       370       380       390       400
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 326 TPTNTWQTALTLQNFNLDIPADDKQRIEAVQEYIASHIDKQWIESLtVGTQRTRrLSPPAFRYQLTELARQAKKRVVLPE 405
Cdd:COG0857                                   316 VELDTYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSR-LGLPRSR-LSPPAFFYYLLERAARAAKRIVLPE 393

                                                         410       420       430       440       450       460       470       480
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 406 GEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDGVEIIDPVTCLEKYVAPMVELRKAKGLTEVVAREQLQ 485
Cdd:COG0857                                   394 GGEDRRILAAAICLLRRIAACVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAAEVYLRRRKKKGVTVAAAQLE 473

                                                         490       500       510       520       530       540       550       560
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 486 DSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDASQLADIAI 565
Cdd:COG0857                                   474 DDVVLYTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVVVGDCACAPNPPPEELALAAI 553

                                                         570       580       590       600       610       620       630       640
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 566 QSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNSPVAGKATV 645
Cdd:COG0857                                   554 ISSSSAAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAAAADVVVAKAKPSPVAGAAAA 633

                                                         650       660       670       680       690       700
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|.
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 646 FVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAKQ 706
Cdd:COG0857                                   634 FVFPFLDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQQ 694
Pta COG0280
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production ...
 385-703 8.33e-171

Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production and conversion];


Pssm-ID: 440049 [Multi-domain]  Cd Length: 320  Bit Score: 491.89  E-value: 8.33e-171
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 385 AFRYQLTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDgVEIIDPVTC--LEKY 462
Cdd:COG0280                                     1 KFFRPLIERAKAAPKRIVFAEGEDERVLRAAQEALDEGLAEPILVGRPEKIEARAEELGLDLSG-FEIIDPEDSprYEEY 79

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 463 VAPMVELRKAKGLTEVVAREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQ 542
Cdd:COG0280                                    80 AEAYYELRKRKGVTPEEARELVRDAAYFAAMMVRLGEADGLVKGAVGTTADLLRPVLQIIGLRPGVKRVSHVFLMELPDR 159

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 543 VLVYGDCAINPDPDASQLADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYD 622
Cdd:COG0280                                   160 LLFITDTAVNIDPTAEQLADIAINAADTARAFGIEPKVALLSASEFGSPKGPSTDKVREATKMARGQIPDLEVDGELQFD 239

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 623 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAI 702
Cdd:COG0280                                   240 AALSPEAAKRKGPDSPVAGDANVLVFPDLEAGNILYKLLQRLAGAEAIGPILLGLAKPVHLLSRGDSVRDIVNSIALAAV 319


                                                  .
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 703 Q 703
Cdd:COG0280                                   320 Q 320
pta TIGR00651
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ...
 401-701 3.87e-166

phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]


Pssm-ID: 273196 [Multi-domain]  Cd Length: 303  Bit Score: 479.24  E-value: 3.87e-166
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 401 VVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDgVEIIDPVTC--LEKYVAPMVELRKAKGLTEV 478
Cdd:TIGR00651                                   1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKAAGCNLDLGH-VVIIDPDVSpdRESYAERYVELRKHKGMTEA 79

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 479 VAREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVYGDCAINPDPDAS 558
Cdd:TIGR00651                                  80 QARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNAE 159

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 559 QLADIAIQSADSAKAFG-IDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIMENVAKSKAPNS 637
Cdd:TIGR00651                                 160 QLAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPNS 239

                                                         250       260       270       280       290       300
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 638 PVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 701
Cdd:TIGR00651                                 240 PVAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAITA 303
PTA_PTB pfam01515
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ...
 386-701 4.87e-158

Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.


Pssm-ID: 396207 [Multi-domain]  Cd Length: 318  Bit Score: 459.09  E-value: 4.87e-158
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 386 FRYQLTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILsDGVEIIDPVT--CLEKYV 463
Cdd:pfam01515                                   1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDL-DGIEIVDPETspRLEEYA 79

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 464 APMVELRKAKGLTEVVAREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQV 543
Cdd:pfam01515                                  80 DFYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGL 159

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 544 LVYGDCAINPDPDASQLADIAIQSADSAKAFG-IDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYD 622
Cdd:pfam01515                                 160 LFFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFD 239

                                                         250       260       270       280       290       300       310
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 623 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTA 701
Cdd:pfam01515                                 240 AALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAITA 318
eutD PRK09653
phosphotransacetylase;
389-706 1.20e-156

phosphotransacetylase;


Pssm-ID: 236609 [Multi-domain]  Cd Length: 324  Bit Score: 455.84  E-value: 1.20e-156
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 389 QLTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILsDGVEIIDPVTC--LEKYVAPM 466
Cdd:PRK09653                                    6 SLKEKAKGKKKKIVLPEGEDERVLKAAKRLQKEGLVEPILLGNPEEIRAKAKELGLDL-DGVEIIDPETYplLEEFAEAF 84

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 467 VELRKAKGLTEVvAREQLQDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVY 546
Cdd:PRK09653                                   85 VELRKGKGTEED-AAELLKDPNYFGTMLVKLGKADGMVSGAIHSTADTLRPALQIIKTKPGVKTVSSVFIMVKGDERYIF 163

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 547 GDCAINPDPDASQLADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIM 626
Cdd:PRK09653                                  164 ADCAVNPNPTAEQLAEIAINSAETAKAFGIDPKVAMLSFSTKGSAKGPEVDKVQEATEIAKELAPDLKIDGELQFDAAFV 243

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 627 ENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQAKQ 706
Cdd:PRK09653                                  244 PEVAAKKAPGSPVAGKANVFVFPSLEAGNIGYKIAQRLGGFEAVGPILQGLNKPVNDLSRGCSVEDIYNLALITAAQAQG 323
PRK07232 PRK07232
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
 389-706 3.44e-90

bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed


Pssm-ID: 235976 [Multi-domain]  Cd Length: 752  Bit Score: 297.78  E-value: 3.44e-90
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 389 QLTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDG--VEIIDPVTC--LEKYVA 464
Cdd:PRK07232                                  430 PIFAKAKKDPKRVVFAEGEEERVLRAAQEVVDEGLAKPILIGRPEVIEARIKKLGLDLKAGvdFEIVNPEDDprYEEYWQ 509

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 465 PMVELRKAKGLTEVVAREQL-QDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQV 543
Cdd:PRK07232                                  510 YYYELLQRKGVTPEDARRLVrRDRTVIGAMMVARGDADAMICGLTGRYHEHLRPVRQVIGLRPGVHTAAAMNALLLKGGN 589

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 544 LVYGDCAINPDPDASQLADIAIQSADSAKAFGIDPRVAMISYST-GSSGQGSdVEKVREATKLAQERRPDLIIDGPLQYD 622
Cdd:PRK07232                                  590 LFIADTYVNEDPTAEELAEIALMAAEEVRRFGIEPRVALLSHSNfGSSDSPS-ARKMREAVELLRERAPDLEVDGEMHGD 668

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 623 AAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAI 702
Cdd:PRK07232                                  669 AALNEEIRKDLYPFSRLKGPANVLVMPNLEAANISYNLLKELGGGVTIGPILLGMAKPVHILTPSATVRRIVNMTALAVV 748


                                                  ....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 703 QAKQ 706
Cdd:PRK07232                                  749 DAQT 752
PRK12862 PRK12862
malic enzyme; Reviewed
 392-704 3.05e-69

malic enzyme; Reviewed


Pssm-ID: 183799 [Multi-domain]  Cd Length: 763  Bit Score: 241.33  E-value: 3.05e-69
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 392 ELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDG--VEIIDPVTC--LEKYVAPMV 467
Cdd:PRK12862                                  441 AAAKAAPKRVVFAEGEDERVLRAAQVVVDEGLAKPILIGRPAVIEARIERAGLRLRPGvdFEIVNPEDDprYRDYWDTYH 520

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 468 ELRKAKGLTEVVAREQL-QDSVVLATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSIFFMLLPDQVLVY 546
Cdd:PRK12862                                  521 ALMGRKGVTPEMARREVrRRTTLIGAMMVKRGEADAMICGTEGRYERHLEFVLQVIGKRPGVRVYAAMSLLILPGRTLFL 600

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 547 GDCAINPDPDASQLADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLIIDGPLQYDAAIM 626
Cdd:PRK12862                                  601 ADTHVNEDPTAEELAEITILAAEEVRRFGIEPKVALLSHSNFGSSDSPSARKMREALEILRERAPDLEVDGEMHGDAALD 680

                                                         250       260       270       280       290       300       310
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 627 ENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSA-NLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQA 704
Cdd:PRK12862                                  681 EELRDRIFPDSRLEGEANLLVFPNLDAANIAYNLLKTAAgNGLAVGPILLGAAKPVHILTPSATVRRIVNMTALAVADA 759
PRK12861 PRK12861
malic enzyme; Reviewed
 385-704 4.53e-47

malic enzyme; Reviewed


Pssm-ID: 183798 [Multi-domain]  Cd Length: 764  Bit Score: 178.54  E-value: 4.53e-47
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 385 AFRYQLTELARQ-----AKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQG--IILSDGVEIIDPV- 456
Cdd:PRK12861                                  430 AFMKPLFAAARQlvrdgGKARIVFTEGEDERVLRAVQVIVDEKLARPILVGRPEVLLARIERFGlrLRLGQDVEVTNPEy 509

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 457 -TCLEKYVAPMVELRKAKGLTEVVAREQLQDSVVL-ATMMLEQAEVDGLVSGAVHTTANTIRPALQLIKTAPGSNLVSSI 534
Cdd:PRK12861                                  510 dERFPQYWTTYWELRCRDGISKEMARVEMRRRLTLiGAMMVRLGDADGMICGTVGEYHNHLRFVDEVIGRKPGASTYAAM 589

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 535 FFMLLPDQVLVYGDCAINPDPDASQLADIAIQSADSAKAFGIDPRVAMISYSTGSSGQGSDVEKVREATKLAQERRPDLI 614
Cdd:PRK12861                                  590 NILLLDQRTVALVDTHVNDNPDAEQIAEFTIAAARQMEWLNLTPKVALLSRSNFGSGSAASGVKMRRALEIVREQAPDLE 669

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 615 IDGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSA-NLISIGPMLQGMRKPVNDLSRGALVDDI 693
Cdd:PRK12861                                  670 ADGEMHGDCALDEGLRARLLPMSPLKGAANLLVCPNVDAGNIAYNLLKTEAgSNVAVGPFLLGVNAPVNILTSSATVRRI 749

                                                         330
                                                  ....*....|.
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 694 VYTIALTAIQA 704
Cdd:PRK12861                                  750 VNMAALTVIEA 760
DRTGG pfam07085
DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated ...
 228-340 3.99e-34

DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated with CBS domains pfam00571, as well as the CbiA domain pfam01656. The function of this domain is unknown. It is named the DRTGG domain after some of the most conserved residues. This domain may be very distantly related to a pair of CBS domains. There are no significant sequence similarities, but its length and association with CBS domains supports this idea (Bateman A, pers. obs.).


Pssm-ID: 429285 [Multi-domain]  Cd Length: 105  Bit Score: 125.69  E-value: 3.99e-34
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 228 DLAKHLGAEILNEGDIEERRLVGITFCARSIPNMLEHFRPGGLLVTSGDRADVIVAACLAamngvKIGALLLTGDVRPDA 307
Cdd:pfam07085                                   1 DIARILGAEVLNGGDGLLRRVGKVVVGAMSVENMLKYLRPGDLVITPGDREDIQLAALEA-----GIAGLILTGGFEPSP 75

                                                          90       100       110
                                                  ....*....|....*....|....*....|...
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 308 SVLKLCQQAmatGLPIMLTPTNTWQTALTLQNF 340
Cdd:pfam07085                                  76 EVLKLAEEL---GLPVLSTPYDTFTTASRINRA 105
AAA_26 pfam13500
AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis ...
 12-225 4.63e-31

AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.


Pssm-ID: 433259 [Multi-domain]  Cd Length: 198  Bit Score: 120.44  E-value: 4.63e-31
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  12 TSVSLGMVRAFERNGLNVNFFKPVAQPRQGEKGPELSTEIIRQGTNASPATPFTLSH--AEKLIGAGK-TDVLLEDIVER 88
Cdd:pfam13500                                  15 TVVSLGLARALKRRGVKVGYWKPVQTGLVEDGDSELVKRLLGLDQSYEDPEPFRLSAplSPHLAARQEgVTIDLEKIIYE 94

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  89 FEShmvDAEIVVVEGLVPTSKQPFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACsnfggSKNKNIIGCVINK 168
Cdd:pfam13500                                  95 LPA---DADPVVVEGAGGLLVPINEDLLNADIAANLGLPVILVARGGLGTINHTLLTLEALR-----QRGIPVLGVILNG 166

                                                         170       180       190       200       210
                                                  ....*....|....*....|....*....|....*....|....*....|....*..
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 169 VGAPLDEAgrsrpdlaemfeanagnashnlevlQVFGKSPMPILGCIPWSAELIAPR 225
Cdd:pfam13500                                 167 VPNPENVR-------------------------TIFAFGGVPVLGAVPYLPDLTAPT 198
PRK05805 PRK05805
phosphate butyryltransferase; Validated
 390-707 4.65e-24

phosphate butyryltransferase; Validated


Pssm-ID: 180267  Cd Length: 301  Bit Score: 103.25  E-value: 4.65e-24
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 390 LTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDgVEIIDpvtclEKyvapmvEL 469
Cdd:PRK05805                                    9 LSKAKEQPPKTISVAVAQDEPVLEAVKEAKELGIANAILVGDKEKIKEIAKEIDMDLED-FEIID-----EK------DN 76

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 470 RKAkgltevvAREqlqdsvvlATMMLEQAEVDGLVSGAVHTtANTIRPALQLIKTAPGSNLVSSIFFMLLP--DQVLVYG 547
Cdd:PRK05805                                   77 RKA-------ALK--------AVELVSSGKADMVMKGLVDT-ANFLRAVLNKEIGLRTGKTMSHVAVFEVPkyDRLLFLT 140

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 548 DCAINPDPDASQLADIAIQSADSAKAFGID-PRVAMISystgssgqgsDVEKVR-------EATKLAQERR----PDLII 615
Cdd:PRK05805                                  141 DAAFNIAPDLKEKIDIINNAVTVAHAIGIEnPKVAPIC----------AVEVVNpkmpatlDAALLSKMSDrgqiKGCIV 210

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 616 DGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLiSIGPMLQGMRKPVNDLSRGALVDDIVY 695
Cdd:PRK05805                                  211 DGPLALDNALSEEAAKHKGIDGPVAGNADILLVPNIEAGNVMYKTLTYFADC-KNGGLLVGTSAPVVLTSRADSHETKLN 289

                                                         330
                                                  ....*....|..
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 696 TIALTAIQAKQL 707
Cdd:PRK05805                                  290 SIALAALVAAKL 301
DTBS cd03109
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ...
 12-188 7.53e-20

dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.


Pssm-ID: 349763 [Multi-domain]  Cd Length: 189  Bit Score: 88.01  E-value: 7.53e-20
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  12 TSVSLGMVRAFERNGLNVNFFKPVAQprQGEKGPELSTEIIRQGTNASPA----TPFTLSH--AEKLIGAGK-TDVLLED 84
Cdd:cd03109                                    15 TVVSAGLARALRKKGIKVGYLKPVQT--GCPGLEDSDAELLRKLAGLLLDleliNPYRFEAplSPHLAAELEgRDIDLEE 92

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  85 IVERFESHMVDAEIVVVEGLVPTSKQPFANDVNYNIAKALDAEMVFVTNPGTDSSEQLKDRLEIACsnfggSKNKNIIGC 164
Cdd:cd03109                                    93 IVRALEELAKSYDVVLVEGAGGLLVPLTEGYLNADLARALGLPVILVARGGLGTINHTLLTLEALK-----SRGLDVAGV 167

                                                         170       180
                                                  ....*....|....*....|....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 165 VINKVgaplDEAGRSRPDLAEMFE 188
Cdd:cd03109                                   168 VLNGI----PPEPEAEADNAETLK 187
PRK08190 PRK08190
bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated
 401-681 4.95e-19

bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated


Pssm-ID: 236180 [Multi-domain]  Cd Length: 466  Bit Score: 90.71  E-value: 4.95e-19
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 401 VVLPEgeEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSdGVEIIDpvtclekyvapmVELRKAkgltevvA 480
Cdd:PRK08190                                  181 VVHPC--DAESLRGALEAAEAGLIEPVLVGPEAKIRAAAEEAGLDLS-GVRIVD------------VPHSHA-------A 238

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 481 REQlqdsvvlATMMLEQAEVDGLVSGAVHT---TANTIRPALQLiKTApgsNLVSSIFFMLLPD--QVLVYGDCAINPDP 555
Cdd:PRK08190                                  239 AAR-------AVALARAGEVEALMKGSLHTdelLSAVVARDSGL-RTE---RRISHVFAMDVPTypRPLLITDAAINIAP 307

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 556 DASQLADIaIQSA-DSAKAFGID-PRVAMISYstgssgqgsdVEKVREA----------TKLAqERRP--DLIIDGPLQY 621
Cdd:PRK08190                                  308 TLEDKRDI-VQNAiDLAHALGVEePKVAILSA----------VETVNPKmpstldaaalCKMA-DRGQitGGIVDGPLAF 375

                                                         250       260       270       280       290       300
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 622 DAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLqGMRKPV 681
Cdd:PRK08190                                  376 DNAISAEAARTKGIVSPVAGQADILVVPDLEAGNMLAKQLTYLAGADAAGIVL-GARVPI 434
PRK07742 PRK07742
phosphate butyryltransferase; Validated
 386-699 1.12e-18

phosphate butyryltransferase; Validated


Pssm-ID: 236086  Cd Length: 299  Bit Score: 87.07  E-value: 1.12e-18
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 386 FRYQLTELARQAKKRVVLPEGEEPRTIEAANICAERGIATPVLLGNPAEIKRVAESQGIILSDGVEIIdpvtclekyvap 465
Cdd:PRK07742                                    3 LEHLIDQAAGQPKKTVAVAVAEDEEVIEAVAKAIELQLARFRLYGNQEKIMGMLQEHGLQTSEHIEII------------ 70

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 466 mvelrkakgltevvAREQLQDSVVLATMMLEQAEVDGLVSGAVhTTANTIRPALQLIKTAPGSNLVSSIFFMLLP--DQV 543
Cdd:PRK07742                                   71 --------------HAQSSAEAAELAVKAVRNGEADVLMKGNV-PTANILKAVLNKEWGLRKGSVLSHVAVFEVPnyDRL 135

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 544 LVYGDCAINPDPDASQLADIAIQSADSAKAFGID-PRVAMISYstgssgqgsdVEKVR-------EATKLAQERR----P 611
Cdd:PRK07742                                  136 IFVTDAAMNIAPDLEQKAAIIQNAVEVARAIGIDlPKVAPLAA----------VEVVNpamqatiDAAALTQMNRrgqiK 205

                                                         250       260       270       280       290       300       310       320
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 612 DLIIDGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSANlISIGPMLQGMRKPVNDLSRGALVD 691
Cdd:PRK07742                                  206 NCVVDGPLALDNAVSQIAAEHKGIVSDVAGKADILLVPTIEAGNVLYKSLVYFAD-AKVGAMIAGAKAPIVLTSRADSAE 284


                                                  ....*...
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 692 DIVYTIAL 699
Cdd:PRK07742                                  285 TKLYSLAL 292
PRK11890 PRK11890
phosphate acetyltransferase; Provisional
 419-686 1.48e-15

phosphate acetyltransferase; Provisional


Pssm-ID: 183361  Cd Length: 312  Bit Score: 78.11  E-value: 1.48e-15
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 419 AERGIATPVLLGNPAEIKRVAESQGIILSDgVEIIDpvtclekyvAPMVELRKAKGLTEVVAREqlqdsvvlatmmleqa 498
Cdd:PRK11890                                   43 AQLGLITPILVGPRARIEAVAAECGLDLSG-YEIVD---------APHSHAAAAKAVELVREGE---------------- 96

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 499 eVDGLVSGAVHTTantirpalQLIK--TAPGSNL-----VSSIFFMLLP--DQVLVYGDCAINPDPDASQLADIAIQSAD 569
Cdd:PRK11890                                   97 -AEALMKGSLHTD--------ELMSavVARDTGLrterrISHVFVMDVPgyPKPLIITDAAVNIAPTLEDKADIVQNAID 167

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 570 SAKAFGID-PRVAMISYstgssgqgsdVEKVR-------EATKLAQ--ERR--PDLIIDGPLQYDAAIMENVAKSKAPNS 637
Cdd:PRK11890                                  168 LAHALGFDePRVAILSA----------VETVNpkipstlDAAALCKmaDRGqiTGAILDGPLAFDNAISPEAARIKGIVS 237

                                                         250       260       270       280
                                                  ....*....|....*....|....*....|....*....|....*....
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 638 PVAGKATVFVFPDLNTGNTTYKAVQRSANLISIGPMLqGMRKPVNDLSR 686
Cdd:PRK11890                                  238 PVAGDADILVVPDLEAGNMLAKQLTFLAGADAAGIVL-GARVPIILTSR 285
BioD COG0132
Dethiobiotin synthetase [Coenzyme transport and metabolism]; Dethiobiotin synthetase is part ...
 12-236 4.23e-03

Dethiobiotin synthetase [Coenzyme transport and metabolism]; Dethiobiotin synthetase is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 439902 [Multi-domain]  Cd Length: 222  Bit Score: 39.37  E-value: 4.23e-03
                                                          10        20        30        40        50        60        70        80
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  12 TSVSLGMVRAFERNGLNVNFFKPVA---QPRQGEKGPElSTEIIRQ--GTNASPAT--PFTLSH-------AEKligAGK 77
Cdd:COG0132                                    16 TVVTAALAAALRAAGLRVGYYKPVQtgcEETDGGLRNG-DAELLRRlsGLPLSYELvnPYRFEEplsphlaARL---EGV 91

                                                          90       100       110       120       130       140       150       160
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59  78 TdVLLEDIVERFESHMVDAEIVVVEG----LVP-TSKQPFAndvnyNIAKALDAEMVFVTNP--GT-----DSSEQLKDR 145
Cdd:COG0132                                    92 P-IDLDKILAALRALAARYDLVLVEGagglLVPlTEDLTLA-----DLAKALGLPVILVVRArlGTinhtlLTVEALRAR 165

                                                         170       180       190       200       210       220       230       240
                                                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 146 -LEIAcsnfggsknkniiGCVINKVGApldeagrsrPDLAEMfeanagnasHNLEVLQVFGksPMPILGCIPWSAEliaP 224
Cdd:COG0132                                   166 gLPLA-------------GIVLNGVPP---------PDLAER---------DNLETLERLT--GAPVLGVLPYLAD---L 209

                                                         250
                                                  ....*....|..
seqsig_MLIPV_56c1eb166e5102850810f0f2106c2d59 225 RAKDLAKHLGAE 236
Cdd:COG0132                                   210 DPEALAAYLDLE 221
 
Blast search parameters
Data Source: Live blast search RID = FXZPG51C016
User Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01   Maximum number of hits: 500

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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