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Conserved domains on  [gi|3879529|emb|CAA88969|]
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Probable holocytochrome-c-type synthase [Caenorhabditis elegans]

Protein Classification

holocytochrome c-type synthase( domain architecture ID 6957)

holocytochrome c-type synthase catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome; may be partial

EC:  4.4.1.17
Gene Ontology:  GO:0004408|GO:0046872|GO:0018063
PubMed:  35243551

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Cyto_heme_lyase super family cl03142
Cytochrome c/c1 heme lyase;
24-253 2.22e-80

Cytochrome c/c1 heme lyase;


The actual alignment was detected with superfamily member pfam01265:

Pssm-ID: 426167  Cd Length: 296  Bit Score: 244.54  E-value: 2.22e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529     24 QHSMAAAGGGSQCPLTPEQRAAASGEncgaggACPVGADKAS---------------INPLNNELEHPNQKPAPDQPFAL 88
Cdd:pfam01265  33 HHKSKSSSPSSASAPPMPPAPTPSPS------ACPVPPDDSPpssspaseqqstlskLNPLNYMPSDLSNERAPGQTVDL 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529     89 PTKREKSTIPKaGTETETWTYPSPQMFWNAMLKKGWrwqdDSLSKSDMENIISIHNANNEEAWREVLKWENLLHP----- 163
Cdd:pfam01265 107 PTEREISSIPK-GDGEGNWEYPSPQQMYNAMLRKGY----TDTPEDAVESMVAVHNFLNEGAWQEILGWERRFAKglarg 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529    164 -------EC---------AEPKLKSFKGDAKNLSPRARFRNlFLGY--------DLPFDRHDWIVDRC---GTKQVQYVI 216
Cdd:pfam01265 182 weicrrgEEnvalelrreEEPRLLRFQGRPKELTPKARMLQ-LLGWlypskfgtEPPFDRHDWYVLRCtpgGQKEVRYVI 260
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 3879529    217 DYYDGGAvDPSSKLFTILDVRPAVNDIGNIWDRMVVA 253
Cdd:pfam01265 261 DYYSGPD-EPTGEPVFYLDVRPALDSPTNAAERLMRW 296
 
Name Accession Description Interval E-value
Cyto_heme_lyase pfam01265
Cytochrome c/c1 heme lyase;
24-253 2.22e-80

Cytochrome c/c1 heme lyase;


Pssm-ID: 426167  Cd Length: 296  Bit Score: 244.54  E-value: 2.22e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529     24 QHSMAAAGGGSQCPLTPEQRAAASGEncgaggACPVGADKAS---------------INPLNNELEHPNQKPAPDQPFAL 88
Cdd:pfam01265  33 HHKSKSSSPSSASAPPMPPAPTPSPS------ACPVPPDDSPpssspaseqqstlskLNPLNYMPSDLSNERAPGQTVDL 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529     89 PTKREKSTIPKaGTETETWTYPSPQMFWNAMLKKGWrwqdDSLSKSDMENIISIHNANNEEAWREVLKWENLLHP----- 163
Cdd:pfam01265 107 PTEREISSIPK-GDGEGNWEYPSPQQMYNAMLRKGY----TDTPEDAVESMVAVHNFLNEGAWQEILGWERRFAKglarg 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529    164 -------EC---------AEPKLKSFKGDAKNLSPRARFRNlFLGY--------DLPFDRHDWIVDRC---GTKQVQYVI 216
Cdd:pfam01265 182 weicrrgEEnvalelrreEEPRLLRFQGRPKELTPKARMLQ-LLGWlypskfgtEPPFDRHDWYVLRCtpgGQKEVRYVI 260
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 3879529    217 DYYDGGAvDPSSKLFTILDVRPAVNDIGNIWDRMVVA 253
Cdd:pfam01265 261 DYYSGPD-EPTGEPVFYLDVRPALDSPTNAAERLMRW 296
 
Name Accession Description Interval E-value
Cyto_heme_lyase pfam01265
Cytochrome c/c1 heme lyase;
24-253 2.22e-80

Cytochrome c/c1 heme lyase;


Pssm-ID: 426167  Cd Length: 296  Bit Score: 244.54  E-value: 2.22e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529     24 QHSMAAAGGGSQCPLTPEQRAAASGEncgaggACPVGADKAS---------------INPLNNELEHPNQKPAPDQPFAL 88
Cdd:pfam01265  33 HHKSKSSSPSSASAPPMPPAPTPSPS------ACPVPPDDSPpssspaseqqstlskLNPLNYMPSDLSNERAPGQTVDL 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529     89 PTKREKSTIPKaGTETETWTYPSPQMFWNAMLKKGWrwqdDSLSKSDMENIISIHNANNEEAWREVLKWENLLHP----- 163
Cdd:pfam01265 107 PTEREISSIPK-GDGEGNWEYPSPQQMYNAMLRKGY----TDTPEDAVESMVAVHNFLNEGAWQEILGWERRFAKglarg 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3879529    164 -------EC---------AEPKLKSFKGDAKNLSPRARFRNlFLGY--------DLPFDRHDWIVDRC---GTKQVQYVI 216
Cdd:pfam01265 182 weicrrgEEnvalelrreEEPRLLRFQGRPKELTPKARMLQ-LLGWlypskfgtEPPFDRHDWYVLRCtpgGQKEVRYVI 260
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 3879529    217 DYYDGGAvDPSSKLFTILDVRPAVNDIGNIWDRMVVA 253
Cdd:pfam01265 261 DYYSGPD-EPTGEPVFYLDVRPALDSPTNAAERLMRW 296
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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