|
Name |
Accession |
Description |
Interval |
E-value |
| SGL |
pfam08450 |
SMP-30/Gluconolaconase/LRE-like region; This family describes a region that is found in ... |
73-287 |
6.50e-27 |
|
SMP-30/Gluconolaconase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.
Pssm-ID: 430002 [Multi-domain] Cd Length: 246 Bit Score: 105.81 E-value: 6.50e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 73 PAGGaasEQFTALPAGSVGNAIRFARDGTMFIADYKKHnIFAIAKGTREPVVWFHSDEM--NQPNDITVARDGTIYASDP 150
Cdd:pfam08450 29 PATG---KETVWDTPGPVGAIAPRDDGGLIVALKDGLA-LLDLATGELTPLADLEDDDWplNRFNDGKVDPDGRFWAGTM 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 151 NW----KGREGHIWRIakSADGTVQGQVmsapRAMGTTNGIDLSPDGKTLYVGESSSGEIWSYTV--RGNELTGAKLVKA 224
Cdd:pfam08450 105 GDdeapGGDPGALYRL--DPDGKLVRLL----DGLTISNGLAWSPDGRTFYFADSPARKIWAYDYdlDGGLLSNRRVFAD 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654690915 225 FQPDTV--DGLRTDVAGRLYVARILKGTIALMKPNGAVEREIALKGKEPTNLAFGGSDGKTVFVT 287
Cdd:pfam08450 179 FKDGLGrpDGMAVDAEGNVWVARWGGGKVVRFDPDGKLLREIELPAKRPTSCAFGGPDLRTLYVT 243
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; |
48-287 |
1.87e-22 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism];
Pssm-ID: 225921 [Multi-domain] Cd Length: 307 Bit Score: 95.14 E-value: 1.87e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 48 EGPAADLDGN-LFVVNFGKpGTIGKLPAGGAASEQFTALPAGSVGNAIRfaRDGTMFIADykkHNIFAIAKGTREPVVWF 126
Cdd:COG3386 28 EGPVWDPDRGaLLWVDILG-GRIHRLDPETGKKRVFPSPGGFSSGALID--AGGRLIACE---HGVRLLDPDTGGKITLL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 127 HSDE----MNQPNDITVARDGTIYASDPNWKGRE-------GHIWRIakSADGTVQGQVmsaPRAMGTTNGIDLSPDGKT 195
Cdd:COG3386 102 AEPEdglpLNRPNDGVVDPDGRIWFGDMGYFDLGkseerptGSLYRV--DPDGGVVRLL---DDDLTIPNGLAFSPDGKT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 196 LYVGESSSGEIWSY-TVRGNELTGAKLVKAF---QPDTVDGLRTDVAGRLYVARILKGT-IALMKPNGAVEREIALKGKE 270
Cdd:COG3386 177 LYVADTPANRIHRYdLDPATGPIGGRRGFVDfdeEPGLPDGMAVDADGNLWVAAVWGGGrVVRFNPDGKLLGEIKLPVKR 256
|
250
....*....|....*..
gi 654690915 271 PTNLAFGGSDGKTVFVT 287
Cdd:COG3386 257 PTNPAFGGPDLNTLYIT 273
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
51-248 |
8.92e-12 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 64.26 E-value: 8.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 51 AADLDGNLFVVNFGK---------PGTIGKLPAGGAASEQFTAlPAGsvgnaIRFARDGTMFIADYKKHNIFAIAKGTRE 121
Cdd:cd05819 61 AVDSDGNLYVADTGNhriqkfdpdGNFLASFGGSGDGDGEFNG-PRG-----IAVDSSGNIYVADTGNHRIQKFDPDGEF 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 122 PVVW----FHSDEMNQPNDITVARDGTIYASDpnwkgREGHiwRIAK-SADGTVQ---GQVMSAPRAMGTTNGIDLSPDG 193
Cdd:cd05819 135 LTTFgsggSGPGQFNGPTGVAVDSDGNIYVAD-----TGNH--RIQVfDPDGNFLttfGSTGTGPGQFNYPTGIAVDSDG 207
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 654690915 194 kTLYVGESSSGEIWSYTVRGNEL--TGAKLVKAFQPDTVDGLRTDVAGRLYVA-----RILK 248
Cdd:cd05819 208 -NIYVADSGNNRVQVFDPDGAGFggNGNFLGSDGQFNRPSGLAVDSDGNLYVAdtgnnRIQV 268
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| SGL |
pfam08450 |
SMP-30/Gluconolaconase/LRE-like region; This family describes a region that is found in ... |
73-287 |
6.50e-27 |
|
SMP-30/Gluconolaconase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.
Pssm-ID: 430002 [Multi-domain] Cd Length: 246 Bit Score: 105.81 E-value: 6.50e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 73 PAGGaasEQFTALPAGSVGNAIRFARDGTMFIADYKKHnIFAIAKGTREPVVWFHSDEM--NQPNDITVARDGTIYASDP 150
Cdd:pfam08450 29 PATG---KETVWDTPGPVGAIAPRDDGGLIVALKDGLA-LLDLATGELTPLADLEDDDWplNRFNDGKVDPDGRFWAGTM 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 151 NW----KGREGHIWRIakSADGTVQGQVmsapRAMGTTNGIDLSPDGKTLYVGESSSGEIWSYTV--RGNELTGAKLVKA 224
Cdd:pfam08450 105 GDdeapGGDPGALYRL--DPDGKLVRLL----DGLTISNGLAWSPDGRTFYFADSPARKIWAYDYdlDGGLLSNRRVFAD 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 654690915 225 FQPDTV--DGLRTDVAGRLYVARILKGTIALMKPNGAVEREIALKGKEPTNLAFGGSDGKTVFVT 287
Cdd:pfam08450 179 FKDGLGrpDGMAVDAEGNVWVARWGGGKVVRFDPDGKLLREIELPAKRPTSCAFGGPDLRTLYVT 243
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; |
48-287 |
1.87e-22 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism];
Pssm-ID: 225921 [Multi-domain] Cd Length: 307 Bit Score: 95.14 E-value: 1.87e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 48 EGPAADLDGN-LFVVNFGKpGTIGKLPAGGAASEQFTALPAGSVGNAIRfaRDGTMFIADykkHNIFAIAKGTREPVVWF 126
Cdd:COG3386 28 EGPVWDPDRGaLLWVDILG-GRIHRLDPETGKKRVFPSPGGFSSGALID--AGGRLIACE---HGVRLLDPDTGGKITLL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 127 HSDE----MNQPNDITVARDGTIYASDPNWKGRE-------GHIWRIakSADGTVQGQVmsaPRAMGTTNGIDLSPDGKT 195
Cdd:COG3386 102 AEPEdglpLNRPNDGVVDPDGRIWFGDMGYFDLGkseerptGSLYRV--DPDGGVVRLL---DDDLTIPNGLAFSPDGKT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 196 LYVGESSSGEIWSY-TVRGNELTGAKLVKAF---QPDTVDGLRTDVAGRLYVARILKGT-IALMKPNGAVEREIALKGKE 270
Cdd:COG3386 177 LYVADTPANRIHRYdLDPATGPIGGRRGFVDfdeEPGLPDGMAVDADGNLWVAAVWGGGrVVRFNPDGKLLGEIKLPVKR 256
|
250
....*....|....*..
gi 654690915 271 PTNLAFGGSDGKTVFVT 287
Cdd:COG3386 257 PTNPAFGGPDLNTLYIT 273
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
51-248 |
8.92e-12 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 64.26 E-value: 8.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 51 AADLDGNLFVVNFGK---------PGTIGKLPAGGAASEQFTAlPAGsvgnaIRFARDGTMFIADYKKHNIFAIAKGTRE 121
Cdd:cd05819 61 AVDSDGNLYVADTGNhriqkfdpdGNFLASFGGSGDGDGEFNG-PRG-----IAVDSSGNIYVADTGNHRIQKFDPDGEF 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 122 PVVW----FHSDEMNQPNDITVARDGTIYASDpnwkgREGHiwRIAK-SADGTVQ---GQVMSAPRAMGTTNGIDLSPDG 193
Cdd:cd05819 135 LTTFgsggSGPGQFNGPTGVAVDSDGNIYVAD-----TGNH--RIQVfDPDGNFLttfGSTGTGPGQFNYPTGIAVDSDG 207
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 654690915 194 kTLYVGESSSGEIWSYTVRGNEL--TGAKLVKAFQPDTVDGLRTDVAGRLYVA-----RILK 248
Cdd:cd05819 208 -NIYVADSGNNRVQVFDPDGAGFggNGNFLGSDGQFNRPSGLAVDSDGNLYVAdtgnnRIQV 268
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
49-287 |
1.23e-11 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 63.88 E-value: 1.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 49 GPAADLDGNLFVVNFGKpGTIGKLPAGGAASEQFTALPAGSVG----NAIRFARDGTMFIADYKKHNIFAIAKGTREPVV 124
Cdd:cd05819 12 GIAVDSSGNIYVADTGN-NRIQVFDPDGNFITSFGSFGSGDGQfnepAGVAVDSDGNLYVADTGNHRIQKFDPDGNFLAS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 125 W----FHSDEMNQPNDITVARDGTIYASDpnwkgREGHiwRIAK-SADGTVQGQVMSAPRAMGTTN---GIDLSPDGkTL 196
Cdd:cd05819 91 FggsgDGDGEFNGPRGIAVDSSGNIYVAD-----TGNH--RIQKfDPDGEFLTTFGSGGSGPGQFNgptGVAVDSDG-NI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 197 YVGESSSGEIWSYTVRGNELT--GAKLVKAFQPDTVDGLRTDVAGRLYVA-----RILKGTIALMKPNGAVEREIALKG- 268
Cdd:cd05819 163 YVADTGNHRIQVFDPDGNFLTtfGSTGTGPGQFNYPTGIAVDSDGNIYVAdsgnnRVQVFDPDGAGFGGNGNFLGSDGQf 242
|
250
....*....|....*....
gi 654690915 269 KEPTNLAFgGSDGKtVFVT 287
Cdd:cd05819 243 NRPSGLAV-DSDGN-LYVA 259
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
45-209 |
1.24e-08 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 55.02 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 45 FGIEGPAADLDGNLFVVNFGK-------P--GTIGKLPAGGAASEQFTAlPAGsvgnaIRFARDGTMFIADYKKHNIFAI 115
Cdd:cd05819 102 NGPRGIAVDSSGNIYVADTGNhriqkfdPdgEFLTTFGSGGSGPGQFNG-PTG-----VAVDSDGNIYVADTGNHRIQVF 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 116 AKGTREPVVW----FHSDEMNQPNDITVARDGTIYASDPNWKgreghiwRI----AKSADGTVQGQVMSAPRAMGTTNGI 187
Cdd:cd05819 176 DPDGNFLTTFgstgTGPGQFNYPTGIAVDSDGNIYVADSGNN-------RVqvfdPDGAGFGGNGNFLGSDGQFNRPSGL 248
|
170 180
....*....|....*....|..
gi 654690915 188 DLSPDGKtLYVGESSSGEIWSY 209
Cdd:cd05819 249 AVDSDGN-LYVADTGNNRIQVF 269
|
|
| NHL |
cd05819 |
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in ... |
76-303 |
2.58e-07 |
|
NHL repeat unit of beta-propeller proteins; The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.
Pssm-ID: 271320 [Multi-domain] Cd Length: 269 Bit Score: 50.78 E-value: 2.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 76 GAASEQFTAlPAGsvgnaIRFARDGTMFIADYKKHNIFAIAKGTREPVVW----FHSDEMNQPNDITVARDGTIYASDpN 151
Cdd:cd05819 1 GTGPGELNN-PQG-----IAVDSSGNIYVADTGNNRIQVFDPDGNFITSFgsfgSGDGQFNEPAGVAVDSDGNLYVAD-T 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 152 WKGReghIWRIakSADGTVQGQV---------MSAPRamgttnGIDLSPDGkTLYVGESSSGEIWSYTVRGNELT--GAK 220
Cdd:cd05819 74 GNHR---IQKF--DPDGNFLASFggsgdgdgeFNGPR------GIAVDSSG-NIYVADTGNHRIQKFDPDGEFLTtfGSG 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 221 LVKAFQPDTVDGLRTDVAGRLYVA-----RILKgtialMKPNGAVEREIALKG------KEPTNLAFGGSDgkTVFVTQR 289
Cdd:cd05819 142 GSGPGQFNGPTGVAVDSDGNIYVAdtgnhRIQV-----FDPDGNFLTTFGSTGtgpgqfNYPTGIAVDSDG--NIYVADS 214
|
250
....*....|....
gi 654690915 290 QGGFVESFRTDQQG 303
Cdd:cd05819 215 GNNRVQVFDPDGAG 228
|
|
| NHL_like_5 |
cd14963 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
53-244 |
9.54e-07 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271333 [Multi-domain] Cd Length: 268 Bit Score: 49.21 E-value: 9.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 53 DLDGNlFVVNFGKPGTI-GKL--PAGGAASEQ---------------FTA-------LPAGSVGNAIR-----FARDGTM 102
Cdd:cd14963 36 DYEGK-FKKSFGGPGTGpGEFkyPYGIAVDSDgniyvadlyngriqvFDPdgkflkyFPEKKDRVKLIspaglAIDDGKL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 103 FIADYKKHNI----------FAIAKGTREPvvwfhsDEMNQPNDITVARDGTIYASDPNwKGR-------EGHIWRIAKS 165
Cdd:cd14963 115 YVSDVKKHKVivfdlegkllLEFGKPGSEP------GELSYPNGIAVDEDGNIYVADSG-NGRiqvfdknGKFIKELNGS 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 166 ADGTvqgQVMSAPRamgttnGIDLSPDGKtLYVGESSSG----------EIWSYTVRGNELTGAKLvkafqPdtvDGLRT 235
Cdd:cd14963 188 PDGK---SGFVNPR------GIAVDPDGN-LYVVDNLSHrvyvfdeqgkELFTFGGRGKDDGQFNL-----P---NGLFI 249
|
....*....
gi 654690915 236 DVAGRLYVA 244
Cdd:cd14963 250 DDDGRLYVT 258
|
|
| NHL_like_5 |
cd14963 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
129-276 |
1.91e-05 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271333 [Multi-domain] Cd Length: 268 Bit Score: 45.36 E-value: 1.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 129 DEMNQPNDITVArDGTIYASDP-NWK----GREG-HIWRIAKSadGTVQGQvMSAPramgttNGIDLSPDGKtLYVGESS 202
Cdd:cd14963 7 DPLNKPMGVAVS-DGRIYVADTnNHRvqvfDYEGkFKKSFGGP--GTGPGE-FKYP------YGIAVDSDGN-IYVADLY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 654690915 203 SGEIWSYTVRGNEL----TGAKLVKAFQPDtvdGLRTDvAGRLYVARILKGTIALMKPNGAVEREIALKGKEPTNLAF 276
Cdd:cd14963 76 NGRIQVFDPDGKFLkyfpEKKDRVKLISPA---GLAID-DGKLYVSDVKKHKVIVFDLEGKLLLEFGKPGSEPGELSY 149
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
35-300 |
3.81e-05 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 225926 [Multi-domain] Cd Length: 381 Bit Score: 44.90 E-value: 3.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 35 VQVTPPGEYTFGIegpAADLDG-NLFVVNFGkPGTIGKLPAGGAASEQFTALPAGSVGNAIRFARDGTMFIADYKKHNIF 113
Cdd:COG3391 24 TAAISLGRGPGGV---AVNPDGtQVYVANSG-SNDVSVIDATSNTVTQSLSVGGVYPAGVAVNPAGNKVYVTTGDSNTVS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 114 AIA-----KGTREPVVWfhsdemnQPNDITVARDG-TIYASDPNwkGREGHIWRIAKSADGTVQ-GQVMSAPRamgttnG 186
Cdd:COG3391 100 VIDtatntVLGSIPVGL-------GPVGLAVDPDGkYVYVANAG--NGNNTVSVIDAATNKVTAtIPVGNTPT------G 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 187 IDLSPDGKTLYVGESSSGEIWSYTVRGNELTGAKLVKAFQPDTVD-GLRTDVAG-RLYVA-------RILKGTIAlmkPN 257
Cdd:COG3391 165 VAVDPDGNKVYVTNSDDNTVSVIDTSGNSVVRGSVGSLVGVGTGPaGIAVDPDGnRVYVAndgsgsnNVLKIDTA---TG 241
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 654690915 258 GAVEREIALKGKEPTNLAFgGSDGKTVFVTQRQGGFVESFRTD 300
Cdd:COG3391 242 NVTATDLPVGSGAPRGVAV-DPAGKAAYVANSQGGTVSVIDGA 283
|
|
| NHL_PKND_like |
cd14952 |
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein ... |
48-151 |
1.00e-04 |
|
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein with a cytosolic kinase domain and an extracellular sensor domain that contains NHL repeats. It plays a key role in the development of central nervous system tuberculosis, by mediating the invasion of host brain endothelia. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271322 [Multi-domain] Cd Length: 247 Bit Score: 42.97 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 48 EGPAADLDGNLFVVNFGKpGTIGKLPAGGAAseqFTALPAGSVGNAIRFARD--GTMFIADYKKHNIFAIAKGTREPVVW 125
Cdd:cd14952 97 TGVAVDAAGNVYVADTGN-NRVLKLAAGSNT---QTVLPFTGLSNPDGVAVDgaGNVYVTDTGNNRVLKLAAGSTTQTVL 172
|
90 100
....*....|....*....|....*..
gi 654690915 126 -FHsdEMNQPNDITVARDGTIYASDPN 151
Cdd:cd14952 173 pFT--GLNSPSGVAVDTAGNVYVTDHG 197
|
|
| NHL_like_3 |
cd14956 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
38-271 |
1.46e-04 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271326 [Multi-domain] Cd Length: 274 Bit Score: 42.65 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 38 TPPGEYTfGIEGPAADLDGNLFVVN--------FGKPGT-IGKLPAGGAASEQFTALpagsvgNAIRFARDGTMFIADYK 108
Cdd:cd14956 7 SGPGQFK-DPRGIAVDADDNVYVADarngriqvFDKDGTfLRRFGTTGDGPGQFGRP------RGLAVDKDGWLYVADYW 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 109 KHNIFAIAKGTREPVVWFHS----DEMNQPNDITVARDGTIYASD-PNwkgreghiWRIAK-SADGTVQGQVMSAPRAMG 182
Cdd:cd14956 80 GDRIQVFTLTGELQTIGGSSgsgpGQFNAPRGVAVDADGNLYVADfGN--------QRIQKfDPDGSFLRQWGGTGIEPG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 183 TTN---GIDLSPDGkTLYVGESSSGEIWSYTVRGNELT--GAKLVKAFQPDTVDGLRTDVAGRLYVARILKGTIALMKPN 257
Cdd:cd14956 152 SFNyprGVAVDPDG-TLYVADTYNDRIQVFDNDGAFLRkwGGRGTGPGQFNYPYGIAIDPDGNVFVADFGNNRIQKFTAD 230
|
250
....*....|....
gi 654690915 258 GAVEREIALKGKEP 271
Cdd:cd14956 231 GTFLTSWGSPGTGP 244
|
|
| NHL_PKND_like |
cd14952 |
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein ... |
49-149 |
2.35e-04 |
|
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein with a cytosolic kinase domain and an extracellular sensor domain that contains NHL repeats. It plays a key role in the development of central nervous system tuberculosis, by mediating the invasion of host brain endothelia. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271322 [Multi-domain] Cd Length: 247 Bit Score: 41.81 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 49 GPAADLDGNLFVVNFGkPGTIGKLPAGgaASEQfTALP--AGSVGNAIRFARDGTMFIADYKKHNIFAIAKGTREPVVwF 126
Cdd:cd14952 140 GVAVDGAGNVYVTDTG-NNRVLKLAAG--STTQ-TVLPftGLNSPSGVAVDTAGNVYVTDHGNNRVLKLAAGSTTPTV-L 214
|
90 100
....*....|....*....|...
gi 654690915 127 HSDEMNQPNDITVARDGTIYASD 149
Cdd:cd14952 215 PFTGLNGPLGVAVDAAGNVYVAD 237
|
|
| NHL_like_6 |
cd14962 |
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ... |
131-287 |
1.61e-03 |
|
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271332 [Multi-domain] Cd Length: 271 Bit Score: 39.49 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 131 MNQPNDITVARDGTIYASDP--------NWKGREGHIWRIAKsadgtvqGQVMSAPRamgttnGIDLSPDGkTLYVGESS 202
Cdd:cd14962 11 LTRPYGVAADGRGRIYVADTgrgavfvfDLPNGKVFVIGNAG-------PNRFVSPI------GVAIDANG-NLYVSDAE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 203 SGEIWSYTVRGNELtgAKLVKAFQPDTVDGLRTDVAG-RLYVARILKGTIALMKPNGAVEREIALKGKE------PTNLA 275
Cdd:cd14962 77 LGKVFVFDRDGKFL--RAIGAGALFKRPTGIAVDPAGkRLYVVDTLAHKVKVFDLDGRLLFDIGKRGSGpgefnlPTDLA 154
|
170
....*....|..
gi 654690915 276 FGGSDgkTVFVT 287
Cdd:cd14962 155 VDRDG--NLYVT 164
|
|
| NHL_PKND_like |
cd14952 |
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein ... |
49-248 |
4.88e-03 |
|
NHL repeat domain of the protein kinase PknD; PknD is a mycobacterial transmembrane protein with a cytosolic kinase domain and an extracellular sensor domain that contains NHL repeats. It plays a key role in the development of central nervous system tuberculosis, by mediating the invasion of host brain endothelia. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.
Pssm-ID: 271322 [Multi-domain] Cd Length: 247 Bit Score: 37.96 E-value: 4.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 49 GPAADLDGNLFVVNFGkPGTIGKLPAGgaaSEQFTALPAGSVGN--AIRFARDGTMFIADYKKHNIFAIAKGTREPVVWF 126
Cdd:cd14952 56 GVAVDAAGTVYVTDFG-NNRVLKLAAG---STTQTVLPFTGLNDptGVAVDAAGNVYVADTGNNRVLKLAAGSNTQTVLP 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 654690915 127 HSDeMNQPNDITVARDGTIYASDPnwkGREghiwRIAKSADGTvqgqvmSAPRAMGTT-----NGIDLSPDGkTLYVGES 201
Cdd:cd14952 132 FTG-LSNPDGVAVDGAGNVYVTDT---GNN----RVLKLAAGS------TTQTVLPFTglnspSGVAVDTAG-NVYVTDH 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 654690915 202 SSGEIWSYTVRGNELTGAKLVKAFQPdtvDGLRTDVAGRLYVA-----RILK 248
Cdd:cd14952 197 GNNRVLKLAAGSTTPTVLPFTGLNGP---LGVAVDAAGNVYVAdrgndRVVK 245
|
|
|