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Conserved domains on  [gi|58865920|ref|NP_001012174|]
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peptidyl-prolyl cis-trans isomerase FKBP5 [Rattus norvegicus]

Protein Classification

FKBP_C and TPR domain-containing protein( domain architecture ID 11991378)

FKBP_C and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
44-135 2.12e-39

FKBP-type peptidyl-prolyl cis-trans isomerase;


:

Pssm-ID: 459735  Cd Length: 94  Bit Score: 136.94  E-value: 2.12e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920    44 EETPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGSLP-KI 122
Cdd:pfam00254   2 PEKAKKGDRVTVHYTGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpVI 81

                          90
                  ....*....|...
gi 58865920   123 PSNATLFFEIELL 135
Cdd:pfam00254  82 PPNATLVFEVELL 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
266-438 3.45e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.27  E-value: 3.45e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYTKAVECCDKALG 345
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKA---LELDPDDAE------------ALYNLGLAYLRLGRYEEALADYEQALE 70

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 346 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQ-------------RKAKEHNERDRRVYANM 412
Cdd:COG0457  71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALlelgrydeaieayERALELDPDDADALYNL 150

                       170       180
                ....*....|....*....|....*.
gi 58865920 413 FKKFAEQDAKEEASKALSKKAVEGAA 438
Cdd:COG0457 151 GIALEKLGRYEEALELLEKLEAAALA 176
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
44-135 2.12e-39

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 136.94  E-value: 2.12e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920    44 EETPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGSLP-KI 122
Cdd:pfam00254   2 PEKAKKGDRVTVHYTGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpVI 81

                          90
                  ....*....|...
gi 58865920   123 PSNATLFFEIELL 135
Cdd:pfam00254  82 PPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 36-137 8.01e-39

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 135.69  E-value: 8.01e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920  36 IVKRVGTSEEtPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGS 115
Cdd:COG0545   4 KVLKEGTGAK-PKAGDTVTVHYTGTLLDGTVFDSSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAYGE 82

                        90       100
                ....*....|....*....|..
gi 58865920 116 AGSLPKIPSNATLFFEIELLDF 137
Cdd:COG0545  83 RGAGGVIPPNSTLVFEVELLDV 104
PRK10902 PRK10902
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
 28-138 5.63e-22

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 236791 [Multi-domain]  Cd Length: 269  Bit Score: 95.22  E-value: 5.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   28 KKDRGVLKIVKRVGTSEeTPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKgqVIKAWDIGVSTMKKGEICHLLC 107
Cdd:PRK10902 143 TTSTGLLYKVEKEGTGE-APKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDG--VIPGWTEGLKNIKKGGKIKLVI 219

                         90       100       110
                 ....*....|....*....|....*....|.
gi 58865920  108 KPEYAYGSAGsLPKIPSNATLFFEIELLDFK 138
Cdd:PRK10902 220 PPELAYGKAG-VPGIPANSTLVFDVELLDVK 249
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
266-438 3.45e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.27  E-value: 3.45e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYTKAVECCDKALG 345
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKA---LELDPDDAE------------ALYNLGLAYLRLGRYEEALADYEQALE 70

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 346 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQ-------------RKAKEHNERDRRVYANM 412
Cdd:COG0457  71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALlelgrydeaieayERALELDPDDADALYNL 150

                       170       180
                ....*....|....*....|....*.
gi 58865920 413 FKKFAEQDAKEEASKALSKKAVEGAA 438
Cdd:COG0457 151 GIALEKLGRYEEALELLEKLEAAALA 176
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 230-397 6.06e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 58.07  E-value: 6.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   230 KPKF-GIEPNAELMYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEY-GLSEK 307
Cdd:TIGR00990 274 KPRPaGLEDSNELDEETGNGQLQLGLKSPESKADESYEEAARAFEKALDLGKLGEKEAIALNLRGTFKCLKGKHlEALAD 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   308 ESKASESF--LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNK 385
Cdd:TIGR00990 354 LSKSIELDprVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFI 433

                         170
                  ....*....|..
gi 58865920   386 AARLQISVCQRK 397
Cdd:TIGR00990 434 FSHIQLGVTQYK 445
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 319-350 7.71e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 7.71e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 58865920    319 AFLNLAMCYLKLREYTKAVECCDKALGLDSAN 350
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
319-347 1.37e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 1.37e-05
                          10        20
                  ....*....|....*....|....*....
gi 58865920   319 AFLNLAMCYLKLREYTKAVECCDKALGLD 347
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELN 31
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 305-403 2.30e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 46.32  E-value: 2.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920  305 SEKESKASESFL-----LAA----------------FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Cdd:PLN03088   3 KDLEDKAKEAFVdddfaLAVdlytqaidldpnnaelYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMK 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 58865920  364 MNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNE 403
Cdd:PLN03088  83 LEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEK 122
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 318-382 4.49e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.23  E-value: 4.49e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 58865920 318 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
44-135 2.12e-39

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 136.94  E-value: 2.12e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920    44 EETPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGSLP-KI 122
Cdd:pfam00254   2 PEKAKKGDRVTVHYTGTLEDGTVFDSSYDRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGpVI 81

                          90
                  ....*....|...
gi 58865920   123 PSNATLFFEIELL 135
Cdd:pfam00254  82 PPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 36-137 8.01e-39

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 135.69  E-value: 8.01e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920  36 IVKRVGTSEEtPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGS 115
Cdd:COG0545   4 KVLKEGTGAK-PKAGDTVTVHYTGTLLDGTVFDSSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPELAYGE 82

                        90       100
                ....*....|....*....|..
gi 58865920 116 AGSLPKIPSNATLFFEIELLDF 137
Cdd:COG0545  83 RGAGGVIPPNSTLVFEVELLDV 104
PRK10902 PRK10902
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
 28-138 5.63e-22

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 236791 [Multi-domain]  Cd Length: 269  Bit Score: 95.22  E-value: 5.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   28 KKDRGVLKIVKRVGTSEeTPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKgqVIKAWDIGVSTMKKGEICHLLC 107
Cdd:PRK10902 143 TTSTGLLYKVEKEGTGE-APKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDG--VIPGWTEGLKNIKKGGKIKLVI 219

                         90       100       110
                 ....*....|....*....|....*....|.
gi 58865920  108 KPEYAYGSAGsLPKIPSNATLFFEIELLDFK 138
Cdd:PRK10902 220 PPELAYGKAG-VPGIPANSTLVFDVELLDVK 249
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
266-438 3.45e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.27  E-value: 3.45e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYTKAVECCDKALG 345
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKA---LELDPDDAE------------ALYNLGLAYLRLGRYEEALADYEQALE 70

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 346 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQ-------------RKAKEHNERDRRVYANM 412
Cdd:COG0457  71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALlelgrydeaieayERALELDPDDADALYNL 150

                       170       180
                ....*....|....*....|....*.
gi 58865920 413 FKKFAEQDAKEEASKALSKKAVEGAA 438
Cdd:COG0457 151 GIALEKLGRYEEALELLEKLEAAALA 176
PRK11570 PRK11570
peptidyl-prolyl cis-trans isomerase; Provisional
 47-136 1.37e-12

peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 183207 [Multi-domain]  Cd Length: 206  Bit Score: 66.74  E-value: 1.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   47 PMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKgqVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGSLPKIPSNA 126
Cdd:PRK11570 117 PARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNG--VIPGWIEALTLMPVGSKWELTIPHELAYGERGAGASIPPFS 194

                         90
                 ....*....|
gi 58865920  127 TLFFEIELLD 136
Cdd:PRK11570 195 TLVFEVELLE 204
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 250-435 3.82e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.29  E-value: 3.82e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 250 FEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVswlemeyglsekeskASESFLLAAFLNLAMCYLK 329
Cdd:COG2956  58 YDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL---------------ELDPDDAEALRLLAEIYEQ 122

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNE------ 403
Cdd:COG2956 123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEaiaale 202

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 58865920 404 -------RDRRVYANMFKKFAEQDAKEEASKALsKKAVE 435
Cdd:COG2956 203 raleqdpDYLPALPRLAELYEKLGDPEEALELL-RKALE 240
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 319-403 1.48e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.86  E-value: 1.48e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 319 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKA 398
Cdd:COG4235  19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98


                ....*
gi 58865920 399 KEHNE 403
Cdd:COG4235  99 GDYAE 103
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
247-438 1.66e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.18  E-value: 1.66e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIvswLEMEYGLSEkeskasesfllaAFLNLAMC 326
Cdd:COG0457  55 LGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKA---LELDPDDAE------------ALYNLGLA 119

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 327 YLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNERDR 406
Cdd:COG0457 120 LLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199

                       170       180       190
                ....*....|....*....|....*....|..
gi 58865920 407 RVYANMFKKFAEQDAKEEASKALSKKAVEGAA 438
Cdd:COG0457 200 LLALEQALRKKLAILTLAALAELLLLALALLL 231
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
266-435 1.80e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.70  E-value: 1.80e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYTKAVECCDKALG 345
Cdd:COG4785  71 DLAQLYYERGVAYDSLGDYDLAIADFDQA---LELDPDLAE------------AYNNRGLAYLLLGDYDAALEDFDRALE 135

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 346 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNERDrRVYANMFKKFAEQDAKEEA 425
Cdd:COG4785 136 LDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALA-LLLEDWATAYLLQGDTEEA 214

                       170
                ....*....|
gi 58865920 426 sKALSKKAVE 435
Cdd:COG4785 215 -RELFKLALA 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 315-403 4.86e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.05  E-value: 4.86e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVC 394
Cdd:COG5010  52 KAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131


                ....*....
gi 58865920 395 QRKAKEHNE 403
Cdd:COG5010 132 LLSLGQDDE 140
SlpA COG1047
Peptidyl-prolyl cis-trans isomerase, FKBP type [Posttranslational modification, protein ...
 50-144 8.42e-10

Peptidyl-prolyl cis-trans isomerase, FKBP type [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440668 [Multi-domain]  Cd Length: 138  Bit Score: 56.65  E-value: 8.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920  50 GDKVYVHYKGKLSNGKKFDSSRDRnEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGsagslpkiPSNATLF 129
Cdd:COG1047   4 GDVVTLHYTLKLEDGEVFDSTFEG-EPLEFLHGAGQLIPGLEEALEGMEVGDKKTVTLPPEEAYG--------ERDPELV 74

                        90
                ....*....|....*
gi 58865920 130 FEIELLDFKGEDLFE 144
Cdd:COG1047  75 QTVPREQFPEDEELE 89
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 275-389 1.61e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 1.61e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 275 GTVYFKGGKYMQAVIQYGKIVSwlemeygLSEKESkasesfllAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGL 354
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALR-------LDPDNA--------DALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL 88

                        90       100       110
                ....*....|....*....|....*....|....*
gi 58865920 355 YRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389
Cdd:COG4235  89 YLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 230-397 6.06e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 58.07  E-value: 6.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   230 KPKF-GIEPNAELMYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEY-GLSEK 307
Cdd:TIGR00990 274 KPRPaGLEDSNELDEETGNGQLQLGLKSPESKADESYEEAARAFEKALDLGKLGEKEAIALNLRGTFKCLKGKHlEALAD 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   308 ESKASESF--LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNK 385
Cdd:TIGR00990 354 LSKSIELDprVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFI 433

                         170
                  ....*....|..
gi 58865920   386 AARLQISVCQRK 397
Cdd:TIGR00990 434 FSHIQLGVTQYK 445
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 318-403 1.17e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 1.17e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 318 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRK 397
Cdd:COG4783  39 EAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRA 118


                ....*.
gi 58865920 398 AKEHNE 403
Cdd:COG4783 119 LGRPDE 124
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 263-382 1.97e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 1.97e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSwlemeygLSEKESkasesfllAAFLNLAMCYLKLREYTKAVECCDK 342
Cdd:COG5010  49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ-------LDPNNP--------ELYYNLALLYSRSGDKDEAKEYYEK 113

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 58865920 343 ALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382
Cdd:COG5010 114 ALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 275-406 2.38e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 2.38e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 275 GTVYFKGGKYMQAVIQYGKIvswLEMEYGLSEkeskasesfllaAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGL 354
Cdd:COG3914 119 GNLLLALGRLEEALAALRRA---LALNPDFAE------------AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEAL 183

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 58865920 355 YRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNERDR 406
Cdd:COG3914 184 NNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR 235
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 317-403 4.01e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.77  E-value: 4.01e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQR 396
Cdd:COG3914 112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191


                ....*..
gi 58865920 397 KAKEHNE 403
Cdd:COG3914 192 DLGRLEE 198
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 274-384 4.26e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.12  E-value: 4.26e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 274 KGTVYFKGGKYMQAVIQYGKIVSwlemeygLSEKESkasesfllAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKG 353
Cdd:COG4783  44 LGEILLQLGDLDEAIVLLHEALE-------LDPDEP--------EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEA 108

                        90       100       110
                ....*....|....*....|....*....|.
gi 58865920 354 LYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384
Cdd:COG4783 109 YLRLARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
326-403 5.71e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.17  E-value: 5.71e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 58865920 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKgDFEKVLEVNPQNKAARLQISVCQRKAKEHNE 403
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDE 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 317-403 6.33e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.35  E-value: 6.33e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQR 396
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83


                ....*..
gi 58865920 397 KAKEHNE 403
Cdd:COG4783  84 KAGDYDE 90
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 277-435 6.91e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 6.91e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 277 VYFKGGKYMQAVIqygkivswlemeYGLSEKESKASESFL---------LAAFLNLAMCYLKLREYTKAVECCDKALGLD 347
Cdd:COG2956   5 VAAALGWYFKGLN------------YLLNGQPDKAIDLLEealeldpetVEAHLALGNLYRRRGEYDRAIRIHQKLLERD 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 348 SANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVC-------------QRKAKEHNERDRRVYANMFK 414
Cdd:COG2956  73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIyeqegdwekaievLERLLKLGPENAHAYCELAE 152

                       170       180
                ....*....|....*....|.
gi 58865920 415 KFAEQDAKEEASKALsKKAVE 435
Cdd:COG2956 153 LYLEQGDYDEAIEAL-EKALK 172
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 248-393 5.60e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 5.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   248 KSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVswlemeyglsekesKASESFLLAAFLnLAMCY 327
Cdd:TIGR02917 275 KNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQIL--------------KYAPNSHQARRL-LASIQ 339

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 58865920   328 LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISV 393
Cdd:TIGR02917 340 LRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGI 405
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
319-382 1.20e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 1.20e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 58865920 319 AFLNLAMCYLKLREYTKAVECcDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382
Cdd:COG3063  28 ALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 278-389 4.55e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.37  E-value: 4.55e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 278 YFKGGKYMQAVIQYGKIVSwlemeyglsekesKASESFLLA-AFLNLAMCYLKLREYTKAVECCDKALGLDSANEK---G 353
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLK-------------RYPNSPLAPdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdA 69

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 58865920 354 LYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389
Cdd:COG1729  70 LLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKE 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 250-384 7.60e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.42  E-value: 7.60e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 250 FEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVS--------WLEM--EYGLSEKESKASESFLLA- 318
Cdd:COG2956  92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKlgpenahaYCELaeLYLEQGDYDEAIEALEKAl 171

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 58865920 319 --------AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384
Cdd:COG2956 172 kldpdcarALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD 245
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 319-350 7.71e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 7.71e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 58865920    319 AFLNLAMCYLKLREYTKAVECCDKALGLDSAN 350
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
319-347 1.37e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 1.37e-05
                          10        20
                  ....*....|....*....|....*....
gi 58865920   319 AFLNLAMCYLKLREYTKAVECCDKALGLD 347
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELN 31
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 335-403 2.21e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 2.21e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 58865920 335 KAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNE 403
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEE 69
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 305-403 2.30e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 46.32  E-value: 2.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920  305 SEKESKASESFL-----LAA----------------FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Cdd:PLN03088   3 KDLEDKAKEAFVdddfaLAVdlytqaidldpnnaelYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMK 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 58865920  364 MNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNE 403
Cdd:PLN03088  83 LEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEK 122
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 281-437 9.32e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 9.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   281 GGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN-------LAMCYLKL--REYTKAVECCDKALGLDSANE 351
Cdd:TIGR02917 114 PGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDprslyakLGLAQLALaeNRFDEARALIDEVLTADPGNV 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   352 KGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNERDrrVYANMFKKFAEQDAKEEASKAL-- 429
Cdd:TIGR02917 194 DALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAE--KHADALLKKAPNSPLAHYLKALvd 271


                  ....*....
gi 58865920   430 -SKKAVEGA 437
Cdd:TIGR02917 272 fQKKNYEDA 280
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 263-423 1.12e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.59  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVswlemeyglsekESKASESFllaaFLNLAMCYLKLREYTKAVECCDK 342
Cdd:TIGR00990 122 ERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAI------------ECKPDPVY----YSNRAACHNALGDWEKVVEDTTA 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   343 ALGLDSANEKGLYRRGEAQLLMNEFESAKGDFekvlevnpqnkaarlqiSVCQRKAKEHNERDRRVYANMFKKFAEQDAK 422
Cdd:TIGR00990 186 ALELDPDYSKALNRRANAYDGLGKYADALLDL-----------------TASCIIDGFRNEQSAQAVERLLKKFAESKAK 248


                  .
gi 58865920   423 E 423
Cdd:TIGR00990 249 E 249
TPR_1 pfam00515
Tetratricopeptide repeat;
352-384 1.80e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 1.80e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 58865920   352 KGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 295-409 3.43e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920   295 VSWLEMEYGLSEKEskasesflLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDF 374
Cdd:TIGR02917 553 VAWLEKAAELNPQE--------IEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 58865920   375 EKVLEVNPQNKAARLQISVCQRKAKEhNERDRRVY 409
Cdd:TIGR02917 625 KKLLALQPDSALALLLLADAYAVMKN-YAKAITSL 658
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 318-382 4.49e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.23  E-value: 4.49e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 58865920 318 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382
Cdd:cd24142   1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
TPR_12 pfam13424
Tetratricopeptide repeat;
315-383 7.01e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 7.01e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 58865920   315 FLLAAFLNLAMCYLKLREYTKAVECCDKAL-------GLDSANEKGLYRR-GEAQLLMNEFESAKGDFEKVLEVNPQ 383
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALeiarrllGPDHPLTATTLLNlGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 352-384 8.43e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 8.43e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 58865920    352 KGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 344-403 1.19e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.48  E-value: 1.19e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 344 LGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNE 403
Cdd:COG2956   1 LLLPVAAALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR 60
PRK15359 PRK15359
type III secretion system chaperone protein SscB; Provisional
 260-381 1.73e-03

type III secretion system chaperone protein SscB; Provisional


Pssm-ID: 185257 [Multi-domain]  Cd Length: 144  Bit Score: 38.83  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920  260 DTKEKLEQAAI----------VKEKGTVYFKGGKYMQAVIQYgkivSWLEMeyglsekeskaSESFLLAAFLNLAMCYLK 329
Cdd:PRK15359   6 DQKNKIPEDILkqllsvdpetVYASGYASWQEGDYSRAVIDF----SWLVM-----------AQPWSWRAHIALAGTWMM 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 58865920  330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
Cdd:PRK15359  71 LKEYTTAINFYGHALMLDASHPEPVYQTGVCLKMMGEPGLAREAFQTAIKMS 122
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
320-453 1.92e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.87  E-value: 1.92e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 320 FLNLAMCYLKLREYTKAVECCDKAL-GLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQI------S 392
Cdd:COG4700  92 RVRLADALLELGRYDEAIELYEEALtGIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFKSSDAHLlyaralE 171

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 58865920 393 VCQR--KAKEHNERDRRVYAN-----MFKKFAEQDAKEEASKALSKKAVEGAAG-----KKHESQTMGEGKAE 453
Cdd:COG4700 172 ALGDleAAEAELEALARRYSGpearyRYAKFLARQGRTAEAKELLEEILDEAKHmpkhyRRLNREWIREAKKL 244
PRK15095 PRK15095
FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional
 53-115 4.68e-03

FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional


Pssm-ID: 237908 [Multi-domain]  Cd Length: 156  Bit Score: 37.76  E-value: 4.68e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 58865920   53 VYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGS 115
Cdd:PRK15095  11 VLVHFTLKLDDGSTAESTRNNGKPALFRLGDGSLSEGLEQQLLGLKVGDKKTFSLEPEAAFGV 73
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
344-403 9.77e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 37.68  E-value: 9.77e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 58865920 344 LGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKEHNE 403
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEE 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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