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Conserved domains on  [gi|302809609|ref|XP_002986497|]
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annexin A4 isoform X2 [Selaginella moellendorffii]

Protein Classification

annexin( domain architecture ID 10446041)

annexin belongs to a family of calcium- and phospholipid-binding proteins that have been implicated in many cellular processes, including channel formation, membrane fusion, vesicle transport, and regulation of phospholipase A2 activity

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
87-151 3.52e-26

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 98.31  E-value: 3.52e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302809609   87 RDAVLIRDAMKGLGTKDKTLIEIICSRTPSQLYYIRQAYQTKYHRSLDKDIQSDTSGDYRKLLLA 151
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLA 65
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
246-311 1.41e-21

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 85.99  E-value: 1.41e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609  246 YFAKVLYDSMKRMGTDDSTLIRVVVTRAEQDMQYIKADFYQKYKKPLESMISGDTSGNYKHFLLSL 311
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
15-80 3.56e-18

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 77.13  E-value: 3.56e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609   15 QDCQALHHAFKGFGCDEKHVIQILAHRNYLQRRELVNAYRSMYGEDLLRRLEKELHGNLEQAVLLW 80
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
171-236 1.73e-17

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 75.20  E-value: 1.73e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609  171 DArELYRAGEGRLGTDESTFIRVFSTRSAAQLHAAFAAYKHLYKRDIDKAIKRETSGDFEDALRLI 236
Cdd:pfam00191   2 DA-ELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
 
Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
87-151 3.52e-26

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 98.31  E-value: 3.52e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302809609   87 RDAVLIRDAMKGLGTKDKTLIEIICSRTPSQLYYIRQAYQTKYHRSLDKDIQSDTSGDYRKLLLA 151
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLA 65
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
246-311 1.41e-21

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 85.99  E-value: 1.41e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609  246 YFAKVLYDSMKRMGTDDSTLIRVVVTRAEQDMQYIKADFYQKYKKPLESMISGDTSGNYKHFLLSL 311
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
100-151 2.92e-21

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 84.77  E-value: 2.92e-21
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 302809609   100 GTKDKTLIEIICSRTPSQLYYIRQAYQTKYHRSLDKDIQSDTSGDYRKLLLA 151
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLA 52
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
15-80 3.56e-18

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 77.13  E-value: 3.56e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609   15 QDCQALHHAFKGFGCDEKHVIQILAHRNYLQRRELVNAYRSMYGEDLLRRLEKELHGNLEQAVLLW 80
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
259-311 7.92e-18

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 75.52  E-value: 7.92e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 302809609   259 GTDDSTLIRVVVTRAEQDMQYIKADFYQKYKKPLESMISGDTSGNYKHFLLSL 311
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
171-236 1.73e-17

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 75.20  E-value: 1.73e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609  171 DArELYRAGEGRLGTDESTFIRVFSTRSAAQLHAAFAAYKHLYKRDIDKAIKRETSGDFEDALRLI 236
Cdd:pfam00191   2 DA-ELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
184-233 3.44e-13

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 63.20  E-value: 3.44e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 302809609   184 GTDESTFIRVFSTRSAAQLHAAFAAYKHLYKRDIDKAIKRETSGDFEDAL 233
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLL 50
ANX smart00335
Annexin repeats;
28-80 1.26e-12

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 61.65  E-value: 1.26e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 302809609    28 GCDEKHVIQILAHRNYLQRRELVNAYRSMYGEDLLRRLEKELHGNLEQAVLLW 80
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
 
Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
87-151 3.52e-26

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 98.31  E-value: 3.52e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 302809609   87 RDAVLIRDAMKGLGTKDKTLIEIICSRTPSQLYYIRQAYQTKYHRSLDKDIQSDTSGDYRKLLLA 151
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLA 65
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
246-311 1.41e-21

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 85.99  E-value: 1.41e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609  246 YFAKVLYDSMKRMGTDDSTLIRVVVTRAEQDMQYIKADFYQKYKKPLESMISGDTSGNYKHFLLSL 311
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
100-151 2.92e-21

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 84.77  E-value: 2.92e-21
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 302809609   100 GTKDKTLIEIICSRTPSQLYYIRQAYQTKYHRSLDKDIQSDTSGDYRKLLLA 151
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLA 52
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
15-80 3.56e-18

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 77.13  E-value: 3.56e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609   15 QDCQALHHAFKGFGCDEKHVIQILAHRNYLQRRELVNAYRSMYGEDLLRRLEKELHGNLEQAVLLW 80
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
259-311 7.92e-18

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 75.52  E-value: 7.92e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 302809609   259 GTDDSTLIRVVVTRAEQDMQYIKADFYQKYKKPLESMISGDTSGNYKHFLLSL 311
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
171-236 1.73e-17

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 75.20  E-value: 1.73e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302809609  171 DArELYRAGEGRLGTDESTFIRVFSTRSAAQLHAAFAAYKHLYKRDIDKAIKRETSGDFEDALRLI 236
Cdd:pfam00191   2 DA-ELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
184-233 3.44e-13

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 63.20  E-value: 3.44e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 302809609   184 GTDESTFIRVFSTRSAAQLHAAFAAYKHLYKRDIDKAIKRETSGDFEDAL 233
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLL 50
ANX smart00335
Annexin repeats;
28-80 1.26e-12

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 61.65  E-value: 1.26e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 302809609    28 GCDEKHVIQILAHRNYLQRRELVNAYRSMYGEDLLRRLEKELHGNLEQAVLLW 80
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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