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Conserved domains on  [gi|2038045155|ref|WP_212743354|]
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class II fructose-bisphosphate aldolase, partial [Brevibacterium sp. 2SA]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10785082)

class II fructose-1,6-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

CATH:  3.20.20.70
EC:  4.1.2.13
Gene Ontology:  GO:0004332|GO:0006096|GO:0008270|GO:0030388
PubMed:  12206759|2199259|1412694
SCOP:  4003234

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 8-264 7.43e-111

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439961  Cd Length: 283  Bit Score: 321.27  E-value: 7.43e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGAlAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:COG0191    18 AVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGL-EYLAAMVRAAAEEASVPVALHLDHGASFELIKRAIDAG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK----DGAHAPGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:COG0191    97 FTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEedgvDVDDAEALYTDPEEAAEFVEETGVDALAVAIG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:COG0191   177 TVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAENPDKYDPR 256

                         250       260
                  ....*....|....*....|.
gi 2038045155 244 KYLAPGREAFAAEVTRLLALF 264
Cdd:COG0191   257 KYLKPAREAMKEVVKEKIRLF 277
 
Name Accession Description Interval E-value
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 8-264 7.43e-111

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 321.27  E-value: 7.43e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGAlAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:COG0191    18 AVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGL-EYLAAMVRAAAEEASVPVALHLDHGASFELIKRAIDAG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK----DGAHAPGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:COG0191    97 FTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEedgvDVDDAEALYTDPEEAAEFVEETGVDALAVAIG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:COG0191   177 TVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAENPDKYDPR 256

                         250       260
                  ....*....|....*....|.
gi 2038045155 244 KYLAPGREAFAAEVTRLLALF 264
Cdd:COG0191   257 KYLKPAREAMKEVVKEKIRLF 277
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
8-264 9.63e-104

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 303.18  E-value: 9.63e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGA-LAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALEL 86
Cdd:pfam01116  16 AVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAGgAEALAALVRAAAEAAGVPVALHLDHGASFELIKEAIEA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  87 GFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK-DGAHAPG-VRTDPAEAVDFAAATGVDALAVAVGS 164
Cdd:pfam01116  96 GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEeDGVVVDEkLYTDPEEAAEFVEATGVDALAVAIGN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 165 SHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETlavdPRLVDPRK 244
Cdd:pfam01116 176 VHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREY----PPNKDPRK 251

                         250       260
                  ....*....|....*....|
gi 2038045155 245 YLAPGREAFAAEVTRLLALF 264
Cdd:pfam01116 252 YLRPAEEAMKEVVKEKIRLF 271
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 8-264 4.95e-101

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 296.36  E-value: 4.95e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGaLAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:cd00947    14 AVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAG-LELLVAMVKAAAERASVPVALHLDHGSSFELIKRAIRAG 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGKDGAHA--PGVRTDPAEAVDFAAATGVDALAVAVGSS 165
Cdd:cd00947    93 FSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVgdEGLLTDPEEAEEFVEETGVDALAVAIGTS 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 166 HAML-ERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRK 244
Cdd:cd00947   173 HGAYkGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALREYLAENPKEFDPRK 252

                         250       260
                  ....*....|....*....|
gi 2038045155 245 YLAPGREAFAAEVTRLLALF 264
Cdd:cd00947   253 YLAPAIEAVKEVVKHKMELF 272
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
8-259 1.14e-76

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 234.62  E-value: 1.14e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGaLAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK12857   19 AVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKYAG-IEYISAMVRTAAEKASVPVALHLDHGTDFEQVMKCIRNG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHA---PGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK12857   98 FTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGtEDDITVderEAAMTDPEEARRFVEETGVDALAIAIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:PRK12857  178 TAHGPYKGEPKLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIREAFVARLREVLEKNPDEIDPR 257

                         250
                  ....*....|....*.
gi 2038045155 244 KYLAPGREAfAAEVTR 259
Cdd:PRK12857  258 KILGPAREA-AKEVIR 272
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 8-252 1.19e-76

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 234.56  E-value: 1.19e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAAS-VPIAVHLDHATDLSLVDEALEL 86
Cdd:TIGR01859  17 AVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSiVPVALHLDHGSSYESCIKAIKA 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  87 GFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHAPGVR-TDPAEAVDFAAATGVDALAVAVGS 164
Cdd:TIGR01859  97 GFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGiEDGVDEKEAElADPDEAEQFVKETGVDYLAAAIGT 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 165 SHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRK 244
Cdd:TIGR01859 177 SHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFTAAIRKVLTEKKDEYDPRK 256


                  ....*...
gi 2038045155 245 YLAPGREA 252
Cdd:TIGR01859 257 ILGPAREA 264
 
Name Accession Description Interval E-value
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 8-264 7.43e-111

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 321.27  E-value: 7.43e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGAlAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:COG0191    18 AVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGL-EYLAAMVRAAAEEASVPVALHLDHGASFELIKRAIDAG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK----DGAHAPGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:COG0191    97 FTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEedgvDVDDAEALYTDPEEAAEFVEETGVDALAVAIG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:COG0191   177 TVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAENPDKYDPR 256

                         250       260
                  ....*....|....*....|.
gi 2038045155 244 KYLAPGREAFAAEVTRLLALF 264
Cdd:COG0191   257 KYLKPAREAMKEVVKEKIRLF 277
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
8-264 9.63e-104

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 303.18  E-value: 9.63e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGA-LAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALEL 86
Cdd:pfam01116  16 AVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAGgAEALAALVRAAAEAAGVPVALHLDHGASFELIKEAIEA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  87 GFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK-DGAHAPG-VRTDPAEAVDFAAATGVDALAVAVGS 164
Cdd:pfam01116  96 GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEeDGVVVDEkLYTDPEEAAEFVEATGVDALAVAIGN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 165 SHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETlavdPRLVDPRK 244
Cdd:pfam01116 176 VHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREY----PPNKDPRK 251

                         250       260
                  ....*....|....*....|
gi 2038045155 245 YLAPGREAFAAEVTRLLALF 264
Cdd:pfam01116 252 YLRPAEEAMKEVVKEKIRLF 271
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 8-264 4.95e-101

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 296.36  E-value: 4.95e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGaLAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:cd00947    14 AVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAG-LELLVAMVKAAAERASVPVALHLDHGSSFELIKRAIRAG 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGKDGAHA--PGVRTDPAEAVDFAAATGVDALAVAVGSS 165
Cdd:cd00947    93 FSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVgdEGLLTDPEEAEEFVEETGVDALAVAIGTS 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 166 HAML-ERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRK 244
Cdd:cd00947   173 HGAYkGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALREYLAENPKEFDPRK 252

                         250       260
                  ....*....|....*....|
gi 2038045155 245 YLAPGREAFAAEVTRLLALF 264
Cdd:cd00947   253 YLAPAIEAVKEVVKHKMELF 272
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
8-259 1.14e-76

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 234.62  E-value: 1.14e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGaLAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK12857   19 AVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKYAG-IEYISAMVRTAAEKASVPVALHLDHGTDFEQVMKCIRNG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHA---PGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK12857   98 FTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGtEDDITVderEAAMTDPEEARRFVEETGVDALAIAIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:PRK12857  178 TAHGPYKGEPKLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIREAFVARLREVLEKNPDEIDPR 257

                         250
                  ....*....|....*.
gi 2038045155 244 KYLAPGREAfAAEVTR 259
Cdd:PRK12857  258 KILGPAREA-AKEVIR 272
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 8-252 1.19e-76

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 234.56  E-value: 1.19e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAAS-VPIAVHLDHATDLSLVDEALEL 86
Cdd:TIGR01859  17 AVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSiVPVALHLDHGSSYESCIKAIKA 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  87 GFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHAPGVR-TDPAEAVDFAAATGVDALAVAVGS 164
Cdd:TIGR01859  97 GFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGiEDGVDEKEAElADPDEAEQFVKETGVDYLAAAIGT 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 165 SHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRK 244
Cdd:TIGR01859 177 SHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFTAAIRKVLTEKKDEYDPRK 256


                  ....*...
gi 2038045155 245 YLAPGREA 252
Cdd:TIGR01859 257 ILGPAREA 264
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
8-252 3.45e-69

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 215.71  E-value: 3.45e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGAlAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK12737   19 AVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGT-DYIVAIAEVAARKYNIPLALHLDHHEDLDDIKKKVRAG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK----DGAHAPGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK12737   98 IRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQeddlVVDEKDAMYTNPDAAAEFVERTGIDSLAVAIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:PRK12737  178 TAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFSDAVKKYFYENPKANDPR 257


                  ....*....
gi 2038045155 244 KYLAPGREA 252
Cdd:PRK12737  258 KYMTPGKAA 266
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 8-264 7.08e-69

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 214.87  E-value: 7.08e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAAS--VPIAVHLDHATDLSLVDEALE 85
Cdd:TIGR00167  19 AIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGLGAISAMVKAMSEAYPygVPVALHLDHGASEEDCAQAVK 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  86 LGFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK----DGAHAPGVRTDPAEAVDFAAATGVDALAVA 161
Cdd:TIGR00167  99 AGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEedgvSVADESALYTDPEEAKEFVKLTGVDSLAAA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 162 VGSSHAMLERT-SRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLV 240
Cdd:TIGR00167 179 IGNVHGVYKGEpKGLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQIAFAAAVRNYYAENKDYY 258

                         250       260
                  ....*....|....*....|....
gi 2038045155 241 DPRKYLAPGREAFAAEVTRLLALF 264
Cdd:TIGR00167 259 DPRVWLRPGEKAMKEVVLEKIKLF 282
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 8-257 1.06e-68

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 214.22  E-value: 1.06e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGaLAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK09195   19 AVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYAG-TEYLLAIVSAAAKQYHHPLALHLDHHEKFDDIAQKVRSG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK----DGAHAPGVRTDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK09195   98 VRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQeddlQVDEADALYTDPAQAREFVEATGIDSLAVAIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:PRK09195  178 TAHGMYKGEPKLDFDRLENIRQWVNIPLVLHGASGLPTKDIQQTIKLGICKVNVATELKIAFSQALKNYLTEHPEANDPR 257

                         250
                  ....*....|....
gi 2038045155 244 KYLAPGREAFAAEV 257
Cdd:PRK09195  258 HYLQPAKSAMKDVV 271
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 8-257 2.07e-64

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 203.36  E-value: 2.07e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAA--SVPIAVHLDHATDLSLVDEALE 85
Cdd:PRK07709   19 AVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMniTVPVAIHLDHGSSFEKCKEAID 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  86 LGFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK-DGAHAPGV-RTDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK07709   99 AGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQeDDVIAEGViYADPAECKHLVEATGIDCLAPALG 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:PRK07709  179 SVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQIEFTKAVREVLNKDQEVYDPR 258

                         250
                  ....*....|....
gi 2038045155 244 KYLAPGREAFAAEV 257
Cdd:PRK07709  259 KFIGPGRDAIKATV 272
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 8-258 2.51e-64

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 203.30  E-value: 2.51e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIA--AAASVPIAVHLDHATDLSLVDEALE 85
Cdd:PRK08610   19 AVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTVVKMVEGLMhdLNITIPVAIHLDHGSSFEKCKEAID 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  86 LGFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK-DGAHAPGV-RTDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK08610   99 AGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQeDDVVADGIiYADPKECQELVEKTGIDALAPALG 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPR 243
Cdd:PRK08610  179 SVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPR 258

                         250
                  ....*....|....*
gi 2038045155 244 KYLAPGREAFAAEVT 258
Cdd:PRK08610  259 KYLGPAREAIKETVK 273
PRK08185 PRK08185
hypothetical protein; Provisional
 8-264 6.49e-62

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 196.87  E-value: 6.49e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGAlaPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK08185   14 AVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLGD--NFFAYVRERAKRSPVPFVIHLDHGATIEDVMRAIRCG 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGKDGAHAPGVR----TDPAEAVDFAAATGVDALAVAVG 163
Cdd:PRK08185   92 FTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTIGNTGTSIEGGVSeiiyTDPEQAEDFVSRTGVDTLAVAIG 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 164 SSHAMLERTSR--LDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVD 241
Cdd:PRK08185  172 TAHGIYPKDKKpeLQMDLLKEINERVDIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKVREILSDNPSLYE 251

                         250       260
                  ....*....|....*....|....
gi 2038045155 242 PRKYLAPGREAfAAEVTRL-LALF 264
Cdd:PRK08185  252 PNQIYPSAIEA-AKEVVRHkMDLF 274
PRK06806 PRK06806
class II aldolase;
8-233 6.93e-58

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 186.50  E-value: 6.93e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISEncVRY-HGALAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALEL 86
Cdd:PRK06806   19 GVGAFSVANMEMVMGAIKAAEELNSPIILQIAE--VRLnHSPLHLIGPLMVAAAKQAKVPVAVHFDHGMTFEKIKEALEI 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  87 GFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK-DGAHAPGVR-TDPAEAVDFAAATGVDALAVAVGS 164
Cdd:PRK06806   97 GFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSeDGSEDIEMLlTSTTEAKRFAEETDVDALAVAIGN 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2038045155 165 SHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETL 233
Cdd:PRK06806  177 AHGMYNGDPNLRFDRLQEINDVVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNSVITAVNNLV 245
gatY PRK07998
class II aldolase;
9-229 5.62e-54

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 176.49  E-value: 5.62e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   9 IGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGaLAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELGF 88
Cdd:PRK07998   20 AGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSG-YDYIYEIVKRHADKMDVPVSLHLDHGKTFEDVKQAVRAGF 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  89 DSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGKDGAHAPGV--RTDPAEAVDFAAATGVDALAVAVGSSH 166
Cdd:PRK07998   99 TSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDDHVSEAdcKTEPEKVKDFVERTGCDMLAVSIGNVH 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2038045155 167 AmLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAV 229
Cdd:PRK07998  179 G-LEDIPRIDIPLLKRIAEVSPVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDLRKAFITTV 240
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
8-252 1.87e-51

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 171.06  E-value: 1.87e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRY----------HGALApiagatLAIAAAASVPIAVHLDHATDL 77
Cdd:PRK07084   25 AIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYanatllrymaQGAVE------YAKELGCPIPIVLHLDHGDSF 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  78 SLVDEALELGFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG--KDGAHAPGVRTDPAEAVDFAAATGV 155
Cdd:PRK07084   99 ELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGveDEVSAEHHTYTQPEEVEDFVKKTGV 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 156 DALAVAVGSSHAML-----ERTSRLDLDLITRLAAAVP-VPLVLHGSS---------------------GVPDAELERAI 208
Cdd:PRK07084  179 DSLAISIGTSHGAYkfkpgQCPPPLRFDILEEIEKRIPgFPIVLHGSSsvpqeyvktineyggklkdaiGIPEEQLRKAA 258

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2038045155 209 GAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRKYLAPGREA 252
Cdd:PRK07084  259 KSAVCKINIDSDGRLAMTAAIRKVFDEKPEEFDPRKYLGPARDE 302
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 8-267 1.88e-51

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 170.45  E-value: 1.88e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGA--LAPIAGATLAIAAAASVPIAVHLDHAtDLSLVDEALE 85
Cdd:PRK07315   19 AVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGykVCKNLIENLVESMGITVPVAIHLDHG-HYEDALECIE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  86 LGFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHAPGvRTDPAEAVDFAAATGVDALAVAVGS 164
Cdd:PRK07315   98 VGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGeEDGIIGKG-ELAPIEDAKAMVETGIDFLAAGIGN 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 165 SHAML-ERTSRLDLDLITRLAAAVP-VPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLA-------- 234
Cdd:PRK07315  177 IHGPYpENWEGLDLDHLEKLTEAVPgFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFANATRKFARdyeaneae 256

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2038045155 235 -VDPRLVDPRKYLAPGREAFAAEVTRLLALFTEA 267
Cdd:PRK07315  257 yDKKKLFDPRKFLAPGVKAIQASVEERIDVFGSA 290
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
3-259 2.40e-51

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 169.83  E-value: 2.40e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   3 RAPASAIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRyHGALAPIAGATLAIAAAASVPIAVHLDHATDLSLVDE 82
Cdd:PRK12738   14 QANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFK-HIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  83 ALELGFDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGKDGAHA----PGVRTDPAEAVDFAAATGVDAL 158
Cdd:PRK12738   93 KVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSvdaeSAFLTDPQEAKRFVELTGVDSL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 159 AVAVGSSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPR 238
Cdd:PRK12738  173 AVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQ 252

                         250       260
                  ....*....|....*....|.
gi 2038045155 239 LVDPRKYLAPGREAFaAEVTR 259
Cdd:PRK12738  253 GNDPRYYMRVGMDAM-KEVVR 272
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
9-252 4.30e-51

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 170.91  E-value: 4.30e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   9 IGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELGF 88
Cdd:PRK09196   20 VPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKYAGEPFLRHLILAAVEEYPHIPVVMHQDHGNSPATCQRAIQLGF 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  89 DSVMYDGAHLP-------YAENCATTAEVVRRAHRRGIGVEAELGEIGG--------KDGAHAPGVR------TDPAEAV 147
Cdd:PRK09196  100 TSVMMDGSLKAdgktpasYEYNVDVTRKVVEMAHACGVSVEGELGCLGSletgmggeEDGHGAEGKLshdqllTDPEEAA 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 148 DFAAATGVDALAVAVGSSHAMLERTSR-----LDLDLITRLAAAVP-VPLVLHGSS---------------------GVP 200
Cdd:PRK09196  180 DFVKKTQVDALAIAIGTSHGAYKFTRKptgdvLAIDRIKEIHARLPnTHLVMHGSSsvpqelldiineyggdmpetyGVP 259

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2038045155 201 DAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRKYLAPGREA 252
Cdd:PRK09196  260 VEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAENPSEFDPRKYLKPAMEA 311
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
8-234 7.76e-51

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 168.39  E-value: 7.76e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHgALAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK06801   19 ALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYI-SLESLVEAVKFEAARHDIPVVLNLDHGLHFEAVVRALRLG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGKDGAHAPGVR-----TDPAEAVDFAAATGVDALAVAV 162
Cdd:PRK06801   98 FSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEAdsakfTDPQLARDFVDRTGIDALAVAI 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2038045155 163 GSSHAMLERTSRLDLDLITRLAAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLA 234
Cdd:PRK06801  178 GNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAALAAVEQRMT 249
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
9-267 2.22e-48

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 162.83  E-value: 2.22e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   9 IGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELGF 88
Cdd:PRK05835   19 VGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVKAGF 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  89 DSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG---------KDgahapGVRTDPAEAVDFAAATGVDALA 159
Cdd:PRK05835   99 TSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGiednisvdeKD-----AVLVNPKEAEQFVKESQVDYLA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 160 VAVGSSHAMLERTS--RLDLDLITRLAAAVPVPLVLHGSSGVPD---------------------AELERAIGAGMAKIN 216
Cdd:PRK05835  174 PAIGTSHGAFKFKGepKLDFERLQEVKRLTNIPLVLHGASAIPDdvrksyldaggdlkgskgvpfEFLQESVKGGINKVN 253

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2038045155 217 VSTHLGSVFTGAVRETLAVDPRLVDPRKYLAPGREAFAAEVTRLLALFTEA 267
Cdd:PRK05835  254 TDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSA 304
PLN02858 PLN02858
fructose-bisphosphate aldolase
 8-264 6.81e-46

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 165.02  E-value: 6.81e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155    8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGAlaPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PLN02858  1115 AVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALKQGGI--PLVSCCIAAAEQASVPITVHFDHGTSKHELLEALELG 1192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   88 FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHAPGVR---TDPAEAVDFAAATGVDALAVAVG 163
Cdd:PLN02858  1193 FDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGtEDGLTVEEYEaklTDVDQAKEFIDETGIDALAVCIG 1272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  164 SSHAMLERTS-RLDLDLITRL---AAAVPVPLVLHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVREtlavdPRL 239
Cdd:PLN02858  1273 NVHGKYPASGpNLRLDLLKELralSSKKGVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRTAYMEALSS-----PKK 1347

                          250       260
                   ....*....|....*....|....*
gi 2038045155  240 VDPRKYLAPGREAFAAEVTRLLALF 264
Cdd:PLN02858  1348 TDLIDVMSAAKEAMKAVVAEKLRLF 1372
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
8-278 6.73e-45

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 154.94  E-value: 6.73e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGALAPIAGATLAIAAAASVPIAVHLDHATDLSLVDEALELG 87
Cdd:PRK13399   19 GVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAGDAMLRHMVLAAAEMYPDIPICLHQDHGNSPATCQSAIRSG 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  88 FDSVMYDGAHLP-------YAENCATTAEVVRRAHRRGIGVEAELG--------EIGGKDGAHAPG------VRTDPAEA 146
Cdd:PRK13399   99 FTSVMMDGSLLAdgktpasYDYNVDVTRRVTEMAHAVGVSVEGELGclgsletgEAGEEDGVGAEGklshdqMLTDPDQA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 147 VDFAAATGVDALAVAVGSSHAMLERTSR-----LDLDLITRLAAAVP-VPLVLHGSS---------------------GV 199
Cdd:PRK13399  179 VDFVQRTGVDALAIAIGTSHGAYKFTRKpdgdiLAIDRIEEIHARLPnTHLVMHGSSsvpqelqeiinayggkmketyGV 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 200 PDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLVDPRKYLAPGREAFAAEVT-RLLALFTEARAHR----PLA 274
Cdd:PRK13399  259 PVEEIQRGIKHGVRKVNIDTDIRLAMTGAIRKVLAEHPSEFDPRKALKPAMKAMTALCKqRFEAFGTAGQASKikvlPLD 338


                  ....
gi 2038045155 275 KPAR 278
Cdd:PRK13399  339 EMAK 342
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 1-257 1.19e-30

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 117.22  E-value: 1.19e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   1 VERAPASAIGAFNVITLESAEAIAAGAESAGRPVIMQISENCVRYHGA---------------LAPIAGATLAIAAAASV 65
Cdd:cd00453     7 VAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGkgvksdvpqgaailgAISGAHHVHQMAEHYGV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  66 PIAVHLDHATDLSL--VDEALELG-----------FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGGK- 131
Cdd:cd00453    87 PVILHTDHCAKKLLpwIDGLLDAGekhfaatgkplFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGCTGGEe 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 132 -----DGAHAPGVRTDPAEAVDFAAATG----VDALAVAVGSSHAMLER-TSRLDLDLITRLAAAVP---------VPLV 192
Cdd:cd00453   167 dgvdnSHMDASALYTQPEDVDYAYTELSkispRFTIAASFGNVHGVYKKgNVVLTPTILRDSQEYVSkkhnlphnsLNFV 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 193 LHGSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRETLAVDPRLV------------------DPRKYLAPGREAFA 254
Cdd:cd00453   247 FHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLqgqlgnpkgedqpnkkyyDPRVWLRAGQTSMI 326


                  ...
gi 2038045155 255 AEV 257
Cdd:cd00453   327 ARL 329
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 8-257 2.26e-11

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 63.28  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155   8 AIGAFNVITLESAEAIAAGAESAGRPVIMQIS---------------ENCVRYHGALApIAGATLAIAAAASVPIAVHLD 72
Cdd:PRK09197   22 ALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSnggaafiagkgvkddGQGAAVLGAIA-GAKHVHEVAEHYGVPVILHTD 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155  73 HATD--LSLVDEALELG-----------FDSVMYDGAHLPYAENCATTAEVVRRAHRRGIGVEAELGEIGG-KDGAHAPG 138
Cdd:PRK09197  101 HCAKklLPWIDGLLDAGekhfaaggkplFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTLEIELGVTGGeEDGVDNSH 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 139 VR-----TDPAeavDFAAAtgVDAL---------AVAVGSSHAMLE------RTSRLDL--DLITRL--AAAVPVPLVLH 194
Cdd:PRK09197  181 EDnsklyTQPE---DVLYA--YEALgkisgrftiAASFGNVHGVYKpgnvklRPEILKDsqEYVSKKfgLPAKPFDFVFH 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2038045155 195 GSSGVPDAELERAIGAGMAKINVSTHLGSVFTGAVRE----------------TLAVDP--RLVDPRKYLAPGREAFAAE 256
Cdd:PRK09197  256 GGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDyyfknydylqgqvgnpEGEDKPnkKYYDPRVWLRAAEASMAAR 335


                  .
gi 2038045155 257 V 257
Cdd:PRK09197  336 L 336
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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