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Conserved domains on  [gi|4557667|ref|NP_000408.1|]
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interleukin-2 receptor subunit alpha isoform 1 precursor [Homo sapiens]

Protein Classification

CCP domain-containing protein (domain architecture ID 10034019)

CCP domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
125-184 4.07e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056  Cd Length: 57  Bit Score: 41.29  E-value: 4.07e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4557667  125 CREPPPWEN-EATERIYHFVVGQMVYYQCVQGYRAlhRGPAESVCKMTHGktrWTQPQLIC 184
Cdd:cd00033   1 CPPPPVPENgTVTGSKGSYSYGSTVTYSCNEGYTL--VGSSTITCTENGG---WSPPPPTC 56
 
Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
125-184 4.07e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056  Cd Length: 57  Bit Score: 41.29  E-value: 4.07e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4557667  125 CREPPPWEN-EATERIYHFVVGQMVYYQCVQGYRAlhRGPAESVCKMTHGktrWTQPQLIC 184
Cdd:cd00033   1 CPPPPVPENgTVTGSKGSYSYGSTVTYSCNEGYTL--VGSSTITCTENGG---WSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
125-184 3.81e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478  Cd Length: 56  Bit Score: 35.58  E-value: 3.81e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4557667     125 CREPPPWEN-EATERIYHFVVGQMVYYQCVQGYRalHRGPAESVCKMTHgktRWTQPQLIC 184
Cdd:smart00032   1 CPPPPDIENgTVTSSSGTYSYGDTVTYSCDPGYT--LIGSSTITCLENG---TWSPPPPTC 56
 
Name Accession Description Interval E-value
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
125-184 4.07e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056  Cd Length: 57  Bit Score: 41.29  E-value: 4.07e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4557667  125 CREPPPWEN-EATERIYHFVVGQMVYYQCVQGYRAlhRGPAESVCKMTHGktrWTQPQLIC 184
Cdd:cd00033   1 CPPPPVPENgTVTGSKGSYSYGSTVTYSCNEGYTL--VGSSTITCTENGG---WSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
125-184 3.81e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478  Cd Length: 56  Bit Score: 35.58  E-value: 3.81e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4557667     125 CREPPPWEN-EATERIYHFVVGQMVYYQCVQGYRalHRGPAESVCKMTHgktRWTQPQLIC 184
Cdd:smart00032   1 CPPPPDIENgTVTSSSGTYSYGDTVTYSCDPGYT--LIGSSTITCLENG---TWSPPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.16
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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