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Conserved domains on  [gi|296490243|tpg|DAA32356.1|]
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collagen, type IV, alpha 4 [Bos taurus]

Protein Classification

C4 domain-containing protein (domain architecture ID 10477384)

C4 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
348-436 3.28e-33

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


:

Pssm-ID: 279721  Cd Length: 109  Bit Score: 121.12  E-value: 3.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296490243  348 GYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANKYSFWLTTVRPDLQFssaPLPDTLKESHAQR 427
Cdd:pfam01413  25 GYSLLMHTGNGEGGGQD-LGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLSTVEESFPK---PMSMTPKAGDEIR 99

                  ....*....
gi 296490243  428 QKISRCQVC 436
Cdd:pfam01413 100 SYISRCSVC 108
 
Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
348-436 3.28e-33

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 279721  Cd Length: 109  Bit Score: 121.12  E-value: 3.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296490243  348 GYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANKYSFWLTTVRPDLQFssaPLPDTLKESHAQR 427
Cdd:pfam01413  25 GYSLLMHTGNGEGGGQD-LGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLSTVEESFPK---PMSMTPKAGDEIR 99

                  ....*....
gi 296490243  428 QKISRCQVC 436
Cdd:pfam01413 100 SYISRCSVC 108
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
341-436 1.24e-28

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 108.63  E-value: 1.24e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296490243   341 PGGASG--*GYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANK-YSFWLTTVRPDLQFsSAPLP 417
Cdd:smart00111  17 PAGWVElwTGYSFLMHTGNGEGHGQD-LGSPGSCLERFRTMPFIECNGR-GVCNYASRNdYSFWLSTIEPSDQF-TAPRP 93
                           90
                   ....*....|....*....
gi 296490243   418 DTLKEShAQRQKISRCQVC 436
Cdd:smart00111  94 MTPKAG-DLRPYISRCQVC 111
 
Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
348-436 3.28e-33

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 279721  Cd Length: 109  Bit Score: 121.12  E-value: 3.28e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296490243  348 GYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANKYSFWLTTVRPDLQFssaPLPDTLKESHAQR 427
Cdd:pfam01413  25 GYSLLMHTGNGEGGGQD-LGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLSTVEESFPK---PMSMTPKAGDEIR 99

                  ....*....
gi 296490243  428 QKISRCQVC 436
Cdd:pfam01413 100 SYISRCSVC 108
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
341-436 1.24e-28

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 108.63  E-value: 1.24e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296490243   341 PGGASG--*GYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFANK-YSFWLTTVRPDLQFsSAPLP 417
Cdd:smart00111  17 PAGWVElwTGYSFLMHTGNGEGHGQD-LGSPGSCLERFRTMPFIECNGR-GVCNYASRNdYSFWLSTIEPSDQF-TAPRP 93
                           90
                   ....*....|....*....
gi 296490243   418 DTLKEShAQRQKISRCQVC 436
Cdd:smart00111  94 MTPKAG-DLRPYISRCQVC 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.15
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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