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Conserved domains on  [gi|1015828397|gb|AMW76342|]
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fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II [synthetic bacterium JCVI-Syn3.0]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10097223)

class II fructose-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

CATH:  3.20.20.70
EC:  4.1.2.13
Gene Ontology:  GO:0004332|GO:0046872|GO:0006096
PubMed:  12206759
SCOP:  4003234

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 12-294 1.92e-141

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


:

Pssm-ID: 238477  Cd Length: 276  Bit Score: 399.59  E-value: 1.92e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  12 AKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLDYLniTVPVALHLD 91
Cdd:cd00947     1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAG-LELLVAMVKAAAERA--SVPVALHLD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  92 HGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQ-GELGDPLQAEEIS 170
Cdd:cd00947    78 HGSSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDeGLLTDPEEAEEFV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 171 K-TGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRDAT 249
Cdd:cd00947   158 EeTGVDALAVAIGTSHGAYKGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAAL 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1015828397 250 RKYVEERkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQG 294
Cdd:cd00947   238 REYLAEN------PKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
 
Name Accession Description Interval E-value
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 12-294 1.92e-141

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 399.59  E-value: 1.92e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  12 AKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLDYLniTVPVALHLD 91
Cdd:cd00947     1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAG-LELLVAMVKAAAERA--SVPVALHLD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  92 HGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQ-GELGDPLQAEEIS 170
Cdd:cd00947    78 HGSSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDeGLLTDPEEAEEFV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 171 K-TGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRDAT 249
Cdd:cd00947   158 EeTGVDALAVAIGTSHGAYKGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAAL 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1015828397 250 RKYVEERkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQG 294
Cdd:cd00947   238 REYLAEN------PKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 9-296 7.03e-133

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 377.89  E-value: 7.03e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVnTVVGMVNGLLDylNITVPVAL 88
Cdd:COG0191     2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLE-YLAAMVRAAAE--EASVPVAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQ---GELGDPLQ 165
Cdd:COG0191    79 HLDHGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDdaeALYTDPEE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEE-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:COG0191   159 AAEfVEETGVDALAVAIGTVHGVYKG-EPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLA 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 245 FRDATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:COG0191   238 FTAAVREYLAENPDK------YDPRKYLKPAREAMKEVVKEKIRLFGSAGKA 283
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 9-296 1.92e-132

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 377.09  E-value: 1.92e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNItVPVAL 88
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSI-VPVAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIG-QGELGDPLQAE 167
Cdd:TIGR01859  80 HLDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEkEAELADPDEAE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 EI-SKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFR 246
Cdd:TIGR01859 160 QFvKETGVDYLAAAIGTSHGKYKG-EPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFT 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1015828397 247 DATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:TIGR01859 239 AAIRKVLTEKKDE------YDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
10-295 1.73e-129

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 369.05  E-value: 1.73e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  10 VNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAI-KYMGGVNTVVGMVNGLLDYLNitVPVAL 88
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAaKYAGGAEALAALVRAAAEAAG--VPVAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGELG-DPLQAE 167
Cdd:pfam01116  79 HLDHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLYtDPEEAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 E-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFR 246
Cdd:pfam01116 159 EfVEATGVDALAVAIGNVHGVYKP-GPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFT 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1015828397 247 DATRKYveerkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGK 295
Cdd:pfam01116 238 AAVREY----------PPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 9-296 1.01e-118

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 342.64  E-value: 1.01e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNITVPVAL 88
Cdd:PRK07315    3 IVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKNLIENLVESMGITVPVAI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQsLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGELGDPLQAEE 168
Cdd:PRK07315   83 HLDHGH-YEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAKA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 169 ISKTGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACK-MPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRD 247
Cdd:PRK07315  162 MVETGIDFLAAGIGNIHGPYPENWEGLDLDHLEKLTEAVPgFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFAN 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 248 ATRKYVEERKDLD---DAKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK07315  242 ATRKFARDYEANEaeyDKKKLFDPRKFLAPGVKAIQASVEERIDVFGSANKA 293
 
Name Accession Description Interval E-value
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 12-294 1.92e-141

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 399.59  E-value: 1.92e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  12 AKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLDYLniTVPVALHLD 91
Cdd:cd00947     1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAG-LELLVAMVKAAAERA--SVPVALHLD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  92 HGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQ-GELGDPLQAEEIS 170
Cdd:cd00947    78 HGSSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDeGLLTDPEEAEEFV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 171 K-TGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRDAT 249
Cdd:cd00947   158 EeTGVDALAVAIGTSHGAYKGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAAL 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1015828397 250 RKYVEERkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQG 294
Cdd:cd00947   238 REYLAEN------PKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 9-296 7.03e-133

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 377.89  E-value: 7.03e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVnTVVGMVNGLLDylNITVPVAL 88
Cdd:COG0191     2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLE-YLAAMVRAAAE--EASVPVAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQ---GELGDPLQ 165
Cdd:COG0191    79 HLDHGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDdaeALYTDPEE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEE-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:COG0191   159 AAEfVEETGVDALAVAIGTVHGVYKG-EPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLA 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 245 FRDATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:COG0191   238 FTAAVREYLAENPDK------YDPRKYLKPAREAMKEVVKEKIRLFGSAGKA 283
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 9-296 1.92e-132

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 377.09  E-value: 1.92e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNItVPVAL 88
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSI-VPVAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIG-QGELGDPLQAE 167
Cdd:TIGR01859  80 HLDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEkEAELADPDEAE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 EI-SKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFR 246
Cdd:TIGR01859 160 QFvKETGVDYLAAAIGTSHGKYKG-EPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFT 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1015828397 247 DATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:TIGR01859 239 AAIRKVLTEKKDE------YDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
10-295 1.73e-129

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 369.05  E-value: 1.73e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  10 VNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAI-KYMGGVNTVVGMVNGLLDYLNitVPVAL 88
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAaKYAGGAEALAALVRAAAEAAG--VPVAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGELG-DPLQAE 167
Cdd:pfam01116  79 HLDHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLYtDPEEAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 E-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFR 246
Cdd:pfam01116 159 EfVEATGVDALAVAIGNVHGVYKP-GPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFT 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1015828397 247 DATRKYveerkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGK 295
Cdd:pfam01116 238 AAVREY----------PPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 9-296 1.11e-123

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 355.09  E-value: 1.11e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNITVPVAL 88
Cdd:TIGR00167   3 LVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGLGAISAMVKAMSEAYPYGVPVAL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGV---IGQGELGDPLQ 165
Cdd:TIGR00167  83 HLDHGASEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGVsvaDESALYTDPEE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEEISK-TGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:TIGR00167 163 AKEFVKlTGVDSLAAAIGNVHGVYKGEPKGLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQIA 242

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 245 FRDATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:TIGR00167 243 FAAAVRNYYAENKDY------YDPRVWLRPGEKAMKEVVLEKIKLFGSANKA 288
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 9-296 1.01e-118

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 342.64  E-value: 1.01e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNITVPVAL 88
Cdd:PRK07315    3 IVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKNLIENLVESMGITVPVAI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQsLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGELGDPLQAEE 168
Cdd:PRK07315   83 HLDHGH-YEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAKA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 169 ISKTGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACK-MPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRD 247
Cdd:PRK07315  162 MVETGIDFLAAGIGNIHGPYPENWEGLDLDHLEKLTEAVPgFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFAN 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 248 ATRKYVEERKDLD---DAKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK07315  242 ATRKFARDYEANEaeyDKKKLFDPRKFLAPGVKAIQASVEERIDVFGSANKA 293
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 9-296 4.56e-104

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 305.05  E-value: 4.56e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNITVPVAL 88
Cdd:PRK07709    3 LVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPVAI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGEL-GDPLQAE 167
Cdd:PRK07709   83 HLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGVIyADPAECK 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 EISK-TGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFR 246
Cdd:PRK07709  163 HLVEaTGIDCLAPALGSVHGPYKG-EPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQIEFT 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1015828397 247 DATRKYveerkdLDDAKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK07709  242 KAVREV------LNKDQEVYDPRKFIGPGRDAIKATVIGKIREFGSNGKA 285
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 9-297 6.78e-104

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 304.60  E-value: 6.78e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVNTVVGMVNGLLDYLNITVPVAL 88
Cdd:PRK08610    3 LVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTVVKMVEGLMHDLNITIPVAI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGEL-GDPLQAE 167
Cdd:PRK08610   83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIyADPKECQ 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 E-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFR 246
Cdd:PRK08610  163 ElVEKTGIDALAPALGSVHGPYKG-EPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASA 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1015828397 247 DATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKAK 297
Cdd:PRK08610  242 KAVRDVLNNDKEV------YDPRKYLGPAREAIKETVKGKIKEFGTSNRAK 286
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
9-296 1.10e-94

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 281.23  E-value: 1.10e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYmGGVNTVVGMVNGLLDylNITVPVAL 88
Cdd:PRK12857    3 LVTVAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKY-AGIEYISAMVRTAAE--KASVPVAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGV-IGQGE--LGDPLQ 165
Cdd:PRK12857   80 HLDHGTDFEQVMKCIRNGFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDItVDEREaaMTDPEE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEE-ISKTGITMLAAGIGNIHGKY---PswwqSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTEL 241
Cdd:PRK12857  160 ARRfVEETGVDALAIAIGTAHGPYkgeP----KLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNI 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1015828397 242 QLAFRDATRKYVEERKDLddakkgFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK12857  236 REAFVARLREVLEKNPDE------IDPRKILGPAREAAKEVIREKIRLFGSAGKA 284
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 9-296 3.58e-88

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 264.68  E-value: 3.58e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLDYLNItvPVAL 88
Cdd:PRK09195    3 LVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYAG-TEYLLAIVSAAAKQYHH--PLAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGE---LGDPLQ 165
Cdd:PRK09195   80 HLDHHEKFDDIAQKVRSGVRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDLQVDEAdalYTDPAQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEE-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:PRK09195  160 AREfVEATGIDSLAVAIGTAHGMYKG-EPKLDFDRLENIRQWVNIPLVLHGASGLPTKDIQQTIKLGICKVNVATELKIA 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 245 FRDATRKYVEERKDLDdakkgfDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK09195  239 FSQALKNYLTEHPEAN------DPRHYLQPAKSAMKDVVSKVIADCGCEGKA 284
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
8-296 1.33e-86

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 260.78  E-value: 1.33e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   8 KLVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYmGGVNTVVGMVNGLLDYLNItvPVA 87
Cdd:PRK12737    2 YIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSY-AGTDYIVAIAEVAARKYNI--PLA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  88 LHLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIG---QGELGDPL 164
Cdd:PRK12737   79 LHLDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVdekDAMYTNPD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 165 QAEE-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQL 243
Cdd:PRK12737  159 AAAEfVERTGIDSLAVAIGTAHGLYKG-EPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKI 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1015828397 244 AFRDATRKYVEERKDLDdakkgfDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK12737  238 AFSDAVKKYFYENPKAN------DPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
tag_bisphos_ald TIGR01858
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ...
 9-296 5.80e-77

class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.


Pssm-ID: 130917  Cd Length: 282  Bit Score: 235.91  E-value: 5.80e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLDYLNItvPVAL 88
Cdd:TIGR01858   1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKHAG-TEYIVALCSAASTTYNM--PLAL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVI---GQGELGDPLQ 165
Cdd:TIGR01858  78 HLDHHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDDLSvdeEDALYTDPQE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEE-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:TIGR01858 158 AKEfVEATGVDSLAVAIGTAHGLYKK-TPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIA 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 245 FRDATRKYVEERkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:TIGR01858 237 FSGAVKAYFAEN------PQANDPRYYMRPGKDAMKKVVRNKINVCGSAGRA 282
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
9-296 5.19e-68

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 214.59  E-value: 5.19e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVnTVVGMVNGLLDY---LNITVP 85
Cdd:PRK07084    9 LVNTREMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANAT-LLRYMAQGAVEYakeLGCPIP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  86 VALHLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQ-GELGDPL 164
Cdd:PRK07084   88 IVLHLDHGDSFELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEhHTYTQPE 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 165 QAEE-ISKTGITMLAAGIGNIHGKY--------PswwqSLSFDTLERLQKACK-MPMVLHGGS----------------- 217
Cdd:PRK07084  168 EVEDfVKKTGVDSLAISIGTSHGAYkfkpgqcpP----PLRFDILEEIEKRIPgFPIVLHGSSsvpqeyvktineyggkl 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 218 ----GIPQEQVKKAISMGIAKINVNTELQLAFRDATRKYveerkdLDDAKKGFDPRKLLKPGYDALKTTFLE-LTNWFGC 292
Cdd:PRK07084  244 kdaiGIPEEQLRKAAKSAVCKINIDSDGRLAMTAAIRKV------FDEKPEEFDPRKYLGPARDELKKLYKHkIINVLGS 317


                  ....
gi 1015828397 293 QGKA 296
Cdd:PRK07084  318 NGKA 321
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
9-295 3.27e-67

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 212.14  E-value: 3.27e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLD-YLNItvPVA 87
Cdd:PRK05835    2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMG-IDMAVGMVKIMCErYPHI--PVA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  88 LHLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVI---GQGELGDPL 164
Cdd:PRK05835   79 LHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISvdeKDAVLVNPK 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 165 QAEEISK-TGITMLAAGIGNIHGKYPSWWQ-SLSFDTLERLQKACKMPMVLHGGS---------------------GIPQ 221
Cdd:PRK05835  159 EAEQFVKeSQVDYLAPAIGTSHGAFKFKGEpKLDFERLQEVKRLTNIPLVLHGASaipddvrksyldaggdlkgskGVPF 238

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1015828397 222 EQVKKAISMGIAKINVNTELQLAFRDATRKYVEERkdlddaKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGK 295
Cdd:PRK05835  239 EFLQESVKGGINKVNTDTDLRIAFIAEVRKVANED------KSQFDLRKFFSPAQLALKNVVKERMKLLGSANK 306
PRK08185 PRK08185
hypothetical protein; Provisional
 13-297 2.00e-66

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 209.20  E-value: 2.00e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  13 KQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGG--VNTVVGMVNglldylNITVPVALHL 90
Cdd:PRK08185    2 KELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLGDnfFAYVRERAK------RSPVPFVIHL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  91 DHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIG---GEEDGVIGQGELGDPLQAE 167
Cdd:PRK08185   76 DHGATIEDVMRAIRCGFTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTIGntgTSIEGGVSEIIYTDPEQAE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 E-ISKTGITMLAAGIGNIHGKYPSWWQ-SLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAF 245
Cdd:PRK08185  156 DfVSRTGVDTLAVAIGTAHGIYPKDKKpELQMDLLKEINERVDIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAF 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1015828397 246 rdatrkYVEERKDLDDAKKGFDPRKLLKPGYDALKTTFLELTNWFGCQGKAK 297
Cdd:PRK08185  236 ------FKKVREILSDNPSLYEPNQIYPSAIEAAKEVVRHKMDLFNSTGKAD 281
PRK06806 PRK06806
class II aldolase;
9-260 5.07e-64

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 202.68  E-value: 5.07e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKY-----MGGVntvvgMVNGLLdylNIT 83
Cdd:PRK06806    3 LVQMKELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAEVRLNHsplhlIGPL-----MVAAAK---QAK 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  84 VPVALHLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQG-ELGD 162
Cdd:PRK06806   75 VPVAVHFDHGMTFEKIKEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEmLLTS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 163 PLQAEE-ISKTGITMLAAGIGNIHGKYPSwWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTEL 241
Cdd:PRK06806  155 TTEAKRfAEETDVDALAVAIGNAHGMYNG-DPNLRFDRLQEINDVVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATAT 233

                         250
                  ....*....|....*....
gi 1015828397 242 QLAFRDATRKYVEERKDLD 260
Cdd:PRK06806  234 FNSVITAVNNLVLNTPYSD 252
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
9-280 4.58e-62

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 197.95  E-value: 4.58e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgVNTVVGMVNGLLDYLNItvPVAL 88
Cdd:PRK12738    3 IISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIA-LEEIYALCSAYSTTYNM--PLAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGE---LGDPLQ 165
Cdd:PRK12738   80 HLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAEsafLTDPQE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 166 AEE-ISKTGITMLAAGIGNIHGKYpSWWQSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:PRK12738  160 AKRfVELTGVDSLAVAIGTAHGLY-SKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIA 238

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1015828397 245 FRDATRKYVEERKDlddakkGFDPRKLLKPGYDALK 280
Cdd:PRK12738  239 FAGAVKAWFAENPQ------GNDPRYYMRVGMDAMK 268
gatY PRK07998
class II aldolase;
9-260 1.39e-61

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 196.52  E-value: 1.39e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKyMGGVNTVVGMVNGLLDYLNitVPVAL 88
Cdd:PRK07998    3 LVNGRILLDRIQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQ-LSGYDYIYEIVKRHADKMD--VPVSL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  89 HLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVIGQGE-LGDPLQAE 167
Cdd:PRK07998   80 HLDHGKTFEDVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDDHVSEADcKTEPEKVK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 168 E-ISKTGITMLAAGIGNIHG--KYPswwqSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLA 244
Cdd:PRK07998  160 DfVERTGCDMLAVSIGNVHGleDIP----RIDIPLLKRIAEVSPVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDLRKA 235

                         250
                  ....*....|....*..
gi 1015828397 245 F-RDATRKYVEERKDLD 260
Cdd:PRK07998  236 FiTTVGKAYVNNHNEAN 252
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
9-296 2.04e-59

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 191.12  E-value: 2.04e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGgvntvvgmVNGLLDYLNI-----T 83
Cdd:PRK06801    3 LISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS--------LESLVEAVKFeaarhD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  84 VPVALHLDHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVI----GQGE 159
Cdd:PRK06801   75 IPVVLNLDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALygeaDSAK 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 160 LGDPLQAEE-ISKTGITMLAAGIGNIHGKY---PswwqSLSFDTLERLQKACKMPMVLHGGSGIPQEQVKKAISMGIAKI 235
Cdd:PRK06801  155 FTDPQLARDfVDRTGIDALAVAIGNAHGKYkgeP----KLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKI 230

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1015828397 236 NVNTELQLAFRDATRKYVEERKDLDDakkgfDPRKLLKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PRK06801  231 NFYTGMSQAALAAVEQRMTHRHAIYD-----EFAELLLGIEEAISDTVAQQMRIFGSAGQA 286
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
9-296 1.71e-56

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 185.54  E-value: 1.71e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYmGGVNTVVGMVNGLLD-YLNItvPVA 87
Cdd:PRK09196    3 LISLRQLLDHAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKY-AGEPFLRHLILAAVEeYPHI--PVV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  88 LHLDHGQSLEMAKKCILAGYSSVMFDGSHFP-------YAENLEMTKELIKFAEEYEVSVEAEIGSIG-------GEEDG 153
Cdd:PRK09196   80 MHQDHGNSPATCQRAIQLGFTSVMMDGSLKAdgktpasYEYNVDVTRKVVEMAHACGVSVEGELGCLGsletgmgGEEDG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 154 VIGQGELG------DPLQAEE-ISKTGITMLAAGIGNIHGKY----PSWWQSLSFDTLERLQKacKMP---MVLHGGSGI 219
Cdd:PRK09196  160 HGAEGKLShdqlltDPEEAADfVKKTQVDALAIAIGTSHGAYkftrKPTGDVLAIDRIKEIHA--RLPnthLVMHGSSSV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 220 PQ---------------------EQVKKAISMGIAKINVNTELQLAFRDATRKYVEERkdlddaKKGFDPRKLLKPGYDA 278
Cdd:PRK09196  238 PQelldiineyggdmpetygvpvEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAEN------PSEFDPRKYLKPAMEA 311

                         330
                  ....*....|....*...
gi 1015828397 279 LKTTFLELTNWFGCQGKA 296
Cdd:PRK09196  312 MKKICKARYEAFGTAGQA 329
PLN02858 PLN02858
fructose-bisphosphate aldolase
 11-296 3.89e-54

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 189.68  E-value: 3.89e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   11 NAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKyMGGVNTVVGMvngLLDYLNITVPVALHL 90
Cdd:PLN02858  1101 STKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALK-QGGIPLVSCC---IAAAEQASVPITVHF 1176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   91 DHGQSLEMAKKCILAGYSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDGVI---GQGELGDPLQAE 167
Cdd:PLN02858  1177 DHGTSKHELLEALELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGTEDGLTveeYEAKLTDVDQAK 1256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  168 E-ISKTGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACK---MPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQL 243
Cdd:PLN02858  1257 EfIDETGIDALAVCIGNVHGKYPASGPNLRLDLLKELRALSSkkgVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRT 1336

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1015828397  244 AFRDATRKyvEERKDLDDAKkgfdprkllKPGYDALKTTFLELTNWFGCQGKA 296
Cdd:PLN02858  1337 AYMEALSS--PKKTDLIDVM---------SAAKEAMKAVVAEKLRLFGSAGKA 1378
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
9-296 6.75e-52

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 173.81  E-value: 6.75e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397   9 LVNAKQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVnTVVGMVNGLLD-YLNItvPVA 87
Cdd:PRK13399    3 LITLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAGDA-MLRHMVLAAAEmYPDI--PIC 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  88 LHLDHGQSLEMAKKCILAGYSSVMFDGSHFP-------YAENLEMTKELIKFAEEYEVSVEAEIGSIG-------GEEDG 153
Cdd:PRK13399   80 LHQDHGNSPATCQSAIRSGFTSVMMDGSLLAdgktpasYDYNVDVTRRVTEMAHAVGVSVEGELGCLGsletgeaGEEDG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 154 VIGQGELG------DPLQAEE-ISKTGITMLAAGIGNIHGKY----PSWWQSLSFDTLERLQKacKMP---MVLHGGSGI 219
Cdd:PRK13399  160 VGAEGKLShdqmltDPDQAVDfVQRTGVDALAIAIGTSHGAYkftrKPDGDILAIDRIEEIHA--RLPnthLVMHGSSSV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 220 PQE---------------------QVKKAISMGIAKINVNTELQLAFRDATRKYveerkdLDDAKKGFDPRKLLKPGYDA 278
Cdd:PRK13399  238 PQElqeiinayggkmketygvpveEIQRGIKHGVRKVNIDTDIRLAMTGAIRKV------LAEHPSEFDPRKALKPAMKA 311

                         330
                  ....*....|....*...
gi 1015828397 279 LKTTFLELTNWFGCQGKA 296
Cdd:PRK13399  312 MTALCKQRFEAFGTAGQA 329
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 13-280 5.95e-49

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 165.75  E-value: 5.95e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  13 KQMVIDAHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIA-TSEGAIKYMG-GVNTVVGMVNGLLDYLNI-------- 82
Cdd:cd00453     2 QKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQfSNGGASFIAGkGVKSDVPQGAAILGAISGahhvhqma 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  83 ---TVPVALHLDH--GQSLEMAKKCILAG-----------YSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGS 146
Cdd:cd00453    82 ehyGVPVILHTDHcaKKLLPWIDGLLDAGekhfaatgkplFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGC 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 147 IGGEEDGV-----IGQGELGDPLQA----EEISK-TGITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACK-------- 208
Cdd:cd00453   162 TGGEEDGVdnshmDASALYTQPEDVdyayTELSKiSPRFTIAASFGNVHGVYKKGNVVLTPTILRDSQEYVSkkhnlphn 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 209 -MPMVLHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRDATRKYVEE------------RKDLDDAKKGFDPRKLLKPG 275
Cdd:cd00453   242 sLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKAneaylqgqlgnpKGEDQPNKKYYDPRVWLRAG 321


                  ....*
gi 1015828397 276 YDALK 280
Cdd:cd00453   322 QTSMI 326
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 19-295 5.34e-35

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 129.41  E-value: 5.34e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  19 AHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGGVN--------TVVGMVNGLLDYLNIT----VPV 86
Cdd:cd00946    11 AKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGlknekqkaSIAGAIAAAHHVRSMAehygVPV 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  87 ALHLDHGQS---------LEMAKKCILAG----YSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEEDG 153
Cdd:cd00946    91 VLHTDHCAKkllpwfdglLEADEEYFKQHgeplFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEMEIGITGGEEDG 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 154 VIGQGELGDPL--QAEEISKT--------GITMLAAGIGNIHGKYPSWWQSLSFDTL--------ERLQKACKMPM--VL 213
Cdd:cd00946   171 VDNSGVDNAELytQPEDVWYVyealskisPNFSIAAAFGNVHGVYKPGNVKLQPEILgehqdyvrEKLGLADDKPLyfVF 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 214 HGGSGIPQEQVKKAISMGIAKINVNTELQLAFRDATRKYVEERKDL----------DDA--KKGFDPRKLLKPGYDALKT 281
Cdd:cd00946   251 HGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYlqgqignpegPDKpnKKYYDPRVWLREGEKSMVA 330

                         330
                  ....*....|....
gi 1015828397 282 TFLELTNWFGCQGK 295
Cdd:cd00946   331 RVKKAFEDLNSVNK 344
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 19-275 1.11e-34

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 128.37  E-value: 1.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  19 AHRHRYAIGHFNINNLEWTKAILEAAEASKTPVIIATSEGAIKYMGG--VNT------VVGMVNG------LLDYLNitV 84
Cdd:PRK09197   16 AKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGkgVKDdgqgaaVLGAIAGakhvheVAEHYG--V 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397  85 PVALHLDHGQS---------LEMAKKCILAG----YSSVMFDGSHFPYAENLEMTKELIKFAEEYEVSVEAEIGSIGGEE 151
Cdd:PRK09197   94 PVILHTDHCAKkllpwidglLDAGEKHFAAGgkplFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTLEIELGVTGGEE 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1015828397 152 DGVIGQGELGDPL--QAEEISKT--------GITMLAAGIGNIHGKYPSWWQSLSFDTLERLQKACK---------MPMV 212
Cdd:PRK09197  174 DGVDNSHEDNSKLytQPEDVLYAyealgkisGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVSkkfglpakpFDFV 253

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1015828397 213 LHGGSGIPQEQVKKAISMGIAKINVNTELQLAFRDATRKYVEERKD-LD-----------DAKKGFDPRKLLKPG 275
Cdd:PRK09197  254 FHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDyLQgqvgnpegedkPNKKYYDPRVWLRAA 328
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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