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Conserved domains on  [gi|140089351|gb|ABO84973|]
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group 5 allergen [Dermatophagoides farinae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Blo-t-5 super family cl13146
Mite allergen Blo t 5; This family of proteins is Blo t 5, an allergen protein from Blomia ...
 19-131 1.24e-29

Mite allergen Blo t 5; This family of proteins is Blo t 5, an allergen protein from Blomia tropicalis mites. This protein shoes strong reactivity with IgE in asthmatic and rhinitis patients. The structure of the protein contains three alpha helices which form a coiled-coil.


The actual alignment was detected with superfamily member pfam11642:

Pssm-ID: 402989  Cd Length: 118  Bit Score: 103.68  E-value: 1.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 140089351   19 GEPKKHDYQNEFDFLLMQRIHEQMRKGEEALLHLQHQINTFEENPTKEMEEQILGEMDTIIALIDGVRGVLNRLMKRTDL 98
Cdd:pfam11642   4 HKPKKDEFRNEFDRLLVEETEEKIDKLEHALLHLSHQLKELEKTKSKELKEQILRELDIALNFIAGAKGHLERELKRTDL 83

                          90       100       110
                  ....*....|....*....|....*....|...
gi 140089351   99 DIFERYNVEIALKSNEILERDLKKEEQRVKKIE 131
Cdd:pfam11642  84 NLLERYNFEEALATGKVLLKDLTELAKKVKAIE 116
 
Name Accession Description Interval E-value
Blo-t-5 pfam11642
Mite allergen Blo t 5; This family of proteins is Blo t 5, an allergen protein from Blomia ...
 19-131 1.24e-29

Mite allergen Blo t 5; This family of proteins is Blo t 5, an allergen protein from Blomia tropicalis mites. This protein shoes strong reactivity with IgE in asthmatic and rhinitis patients. The structure of the protein contains three alpha helices which form a coiled-coil.


Pssm-ID: 402989  Cd Length: 118  Bit Score: 103.68  E-value: 1.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 140089351   19 GEPKKHDYQNEFDFLLMQRIHEQMRKGEEALLHLQHQINTFEENPTKEMEEQILGEMDTIIALIDGVRGVLNRLMKRTDL 98
Cdd:pfam11642   4 HKPKKDEFRNEFDRLLVEETEEKIDKLEHALLHLSHQLKELEKTKSKELKEQILRELDIALNFIAGAKGHLERELKRTDL 83

                          90       100       110
                  ....*....|....*....|....*....|...
gi 140089351   99 DIFERYNVEIALKSNEILERDLKKEEQRVKKIE 131
Cdd:pfam11642  84 NLLERYNFEEALATGKVLLKDLTELAKKVKAIE 116
 
Name Accession Description Interval E-value
Blo-t-5 pfam11642
Mite allergen Blo t 5; This family of proteins is Blo t 5, an allergen protein from Blomia ...
 19-131 1.24e-29

Mite allergen Blo t 5; This family of proteins is Blo t 5, an allergen protein from Blomia tropicalis mites. This protein shoes strong reactivity with IgE in asthmatic and rhinitis patients. The structure of the protein contains three alpha helices which form a coiled-coil.


Pssm-ID: 402989  Cd Length: 118  Bit Score: 103.68  E-value: 1.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 140089351   19 GEPKKHDYQNEFDFLLMQRIHEQMRKGEEALLHLQHQINTFEENPTKEMEEQILGEMDTIIALIDGVRGVLNRLMKRTDL 98
Cdd:pfam11642   4 HKPKKDEFRNEFDRLLVEETEEKIDKLEHALLHLSHQLKELEKTKSKELKEQILRELDIALNFIAGAKGHLERELKRTDL 83

                          90       100       110
                  ....*....|....*....|....*....|...
gi 140089351   99 DIFERYNVEIALKSNEILERDLKKEEQRVKKIE 131
Cdd:pfam11642  84 NLLERYNFEEALATGKVLLKDLTELAKKVKAIE 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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