Conserved Protein Domain Family
Brr6_like_C_C
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smart01042: Brr6_like_C_C 
Di-sulfide bridge nucleocytoplasmic transport domain
Brr6_like_C_C is the highly conserved C-terminal region of a group of proteins found in fungi. It carries four highly conserved cysteine residues. It is suggested that members of the family interact with each other via di-sulfide bridges to form a complex which is involved in nucleocytoplasmic transport.
Links
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Statistics
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PSSM-Id: 198110
Aligned: 26 rows
Threshold Bit Score: 105.408
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_011267     47 IAEYIQLFFNFIIGTIGLSLAIKFILMIRNDVNLKLEHNVREELDKIATCKSRYFENQC---EPHM-RVPALEVRCNEWS 122 Saccharomyces c...
XP_001383173 230 LSLYLQLFFNLLLISIVLYFVFIFIKTIRADINHKLEVYISNAFAEIAKCERAYQRNNC---NR---RAPLLEAKCTEWE 303 Pichia stipitis...
XP_570985    201 LLGYLQFFVNTSIVLFCIYLAILFVLTVRRDVKDKMNEYSVEILQEIAECTNMYLTNMC---SSN--RIPHMDAPCRAWE 275 Cryptococcus ne...
XP_757598    227 LLGYAQLIFNASILSAFLYLLFHVVRTVQKDVAEKVRSYEMDILSEITTCAAAYTANRC---GTDL-QAPALASACKNWE 302 Ustilago maydis...
XP_382974    244 LYRWVKLLVNFFLVSVFVYIGWSIVSTVKTDIENANEMARIEIMGRITECQTQYTINGC---SRND-RPPVIAKHCDEWF 319 Gibberella zeae...
XP_461111    205 lslylqllfnlllIGVILYLLFIFIRTIKSDISHKLETYTSDAIQEISLCSREYYRNKCsieDGHK-RVPALEKACTVWS 283 Debaryomyces ha...
XP_665834    181 tHEFIRLIFNIIIVFITLYIIFGIIFVIKNDIESKIQISITNILDEMNICSKHYVDNKC---HPEQ-RVPAMESKCTEWE 256 Cryptosporidium...
NP_593955    119 VSGYLQLMFNACVASIFLYFLFKIVFGIQNDVRNRVEYHKILQEEQAADCQREYLSINC---DSPG---PAIFEVCQKLK 192 Schizosaccharom...
XP_001350629 187 IQRWIRVIFNIIITSLIVTLIYYIFISVREDINKKVAIQVQNVKEESNSCRKQYNAHKC---GT-V-NLPLLNEKCEEWA 261 Plasmodium falc...
XP_765336    266 INSWLKTILNIIVTFILIYILIVIFIILRKDIINHINNNKAVVHNKSQICFNEYNKNKC---N--ViKIPAMESKCKEWE 340 Theileria parva...

NP_011267    123 KCMNKEIVSGSDyqwAKAWARTLAEVINAFFEAFSIRSFLFILISIIGIIFVTNTSF--GSYR 183 Saccharomyces cerevisiae S288c
XP_001383173 304 KCMNSDPQLIGK---SKITAETFADIVNGFIRPISWKSLVFLVCLIFGSLLVTNLAF--GSYR 361 Pichia stipitis CBS 6054
XP_570985    276 ACMNRDPTVVGR---INIIAETFAGVINSFVEPISWKTMSFTLVTLTFLVILTNSAL--FNLR 333 Cryptococcus neoformans var. neo...
XP_757598    303 RCSARDPAVVGT---ARVTAETFAEILNGFVDSVSWKTMFFTLICLSIVVGATNSFL--SFFR 360 Ustilago maydis 521
XP_382974    320 ECMTQNPEAIMR---VKVTAKQIAEIINEFSDAMNLKAWGFFFAVLIFCAFANNFFL--GGYi 377 Gibberella zeae PH-1
XP_461111    284 KCMNRDPQLIGK---SKITAETFADIVNGFVKPITWKSLFFMNFMIFGSLFITNIAL--GSYR 341 Debaryomyces hansenii CBS767
XP_665834    257 RCMSQNPTIIARk--SIFTAQIIGEIINTFLDQISFKSALFIFGFIIALIIGNYFVL--SSaf 315 Cryptosporidium hominis TU502
NP_593955    193 QCKMESSNNVGS---TKLAALVFAEIIDAFISHISYKTMVFSLILVFGSLLTSNYAF--GLYR 250 Schizosaccharomyces pombe 972h-
XP_001350629 262 KCMKTDYKLYQDi--SFLSAQMLGQIINTFIVQFEWKSICVIAFIFLLIFIGSNYALsiGGYR 322 Plasmodium falciparum 3D7
XP_765336    341 LCMKKDSLVYEDv--SSISVEIIGSLINKLINQLDLKAILFLIIIILLIIIIK--------IK 393 Theileria parva strain Muguga
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