2XS1_A        10 FISVQLKKTSEVDL--AKPLVKFIQQTYpsgG------EEQAQY--CRAA----EELSKLRRAA-VGRp------lD--K 66   human
NP_001096412   5 FHRNPLKATAPVSF-------NFYGVAS---T------QAASKI--CSDLrstrARLLELFSDI------------T--C 52   western clawed...
XP_002717538   5 FHRNPLKATAPVSF-------NYYGVIT---G------PPASKI--CNDLrssrARLLELFTDLsCNP--------E--M 56   rabbit
CAG12984       5 FHRNPLKATAPVSF-----------NFY---Gv----aGSPAA---NKIC----NDLRTTRARL-LDMft----diT--C 52   spotted green ...
NP_505261      5 FHRNPIKPTEFVKF----DLKGVLTTDT---C--------------SKIC----GEL-RLRRDK-LVS--------QfkN 49   nematode
XP_002132176  46 LFNDPLASPDKMESv-SSDYFSLIQGLF---Evpa-ptTDDASTsqTETT----TEIEDSKTEK-EKDnk-----kD--K 108  Ciona intestin...
XP_642244     60 FFSTKARDLTNIDt--AELLKSV--ETY---CsllgglIGSKVYqpTITT----DNIAAATTAA-TATpvsnfeklQ--L 125  Dictyostelium ...
XP_001466254  11 LPIIPVRQTE------KPGVNSQVEVDL---Ssa--ekKDIDKK--RDAC----IDFFEDFRKH-LSRkgnsvddkL--S 70   Leishmania inf...
XP_843818     26 SIPPNVKRSFELRRaeCIAKFGSVRDQF----------KQSNNY--ATGF----WKNFEEREKV-INC------------ 76   Trypanosoma br...
XP_001707973   7 ALALPLRVPA--D---DNALLKAIQNMG---Dgl--paSASSDL--VQTI----ERYSALRTD----------------- 53   Giardia lambli...

2XS1_A        67 HEGALETLL-R-YYDQI-CSIEPKFPFSENQIC-----------L----T------------------FTW-KDAF--Dk 107  human
NP_001096412  53 NHEMMKNATdA-YFSLL-LGFIDSLDGGTQDNK-----------LryiqN------------------FKW-TDTL--Q- 97   western clawed...
XP_002717538  57 MKNAADL-----YFSLL-QGFINSSDESTQESK-----------LryiqN------------------FKW-TDTL--Q- 97   rabbit
CAG12984      53 NPEVMKNATdA-YFSLL-QGFITSLDGTTQENK-----------MrfiqN------------------FKW-TDTL--Q- 97   spotted green ...
NP_505261     50 ASNDLEEVT-K-EFNEY-LRLFAGFLIEIQSSM-----------V----ElenkdagnknskliplirFKW-GNSM--L- 107  nematode
XP_002132176 109 SKTEDERPV-G-------MAITLKTFFK----------------------------------------FKW-TQTLy-V- 137  Ciona intestin...
XP_642244    126 NEQPRDNDE-E-YNSEEgDDKLEKFNNEKVKNNnnkgsdairknL----R------------------FSW-TNVF---- 176  Dictyostelium ...
XP_001466254  71 TSAGCEKYV-KdLVDLV-DAYTVSLANAVSKTPrfa------slQ----Y------------------YHW-SSSL---- 115  Leishmania inf...
XP_843818     77 ---VVDAVN-D-YAKEL-AALLYHYPVLADG-------------Y----Y------------------YCW-TPCL---- 110  Trypanosoma br...
XP_001707973  54 -VKNMDSLK-EaYSLAL--PLAKQLPWASKEFKeli------sqH----S------------------HHWiFEEAaaT- 100  Giardia lambli...

2XS1_A       108 gslfgGSVk-LALASLGYEKSCVLFNCAALASQIAAEQ-NL------D---NDEGLK---IAAKHYQFASGAFLHI---- 169  human
NP_001096412  98 -----GNAp-SAQQDAVFELVSMGFNVALWYTKYASRL-AG------KediTEEEAK---EVHRSLKIAAGVFKHL---- 157  western clawed...
XP_002717538  98 -----GQVp-SAQQDAVFELISMGFNVALWYTKYASRL-AG------KeniTEDEAK---DVHRSLKIAAGIFKHL---- 157  rabbit
CAG12984      98 -----GNTp-SAQQDAVFELVSMAFNVGLWYTKFASRL-AG------KeniTEVEAK---DVHRSLKVAAGIFKAL---- 157  spotted green ...
NP_505261    108 -----PQAa-TEVSDTWFEALSMIQCMAMWLTKHAASM-AGkd---eV---RESDAK---ECLQCLRQAGGMFQYV---- 167  nematode
XP_002132176 138 -----GKPp-LVEDDAEFDFVNMGINVALWYTKHAAKLaaq-------pelKMEDAK---EIHSCLKKAAGMFKEFk--- 198  Ciona intestin...
XP_642244    177 -----GSDrsITSSDTLVEYMSILFNLGIWYLGYSEYIvSnrcsp--tdglPEEDRQ---KVYDFLLKSAGIFDYLcklr 246  Dictyostelium ...
XP_001466254 116 -----TDKqeMAFDDYRYELLGVYYNVGAILMNIAQYLlCvrvtvgtlsflEKDAYRaliKASAYFHFCADIVDNM---- 186  Leishmania inf...
XP_843818    111 -----SPQetIYFDDFRYDLQNMYFNVGVILVNVSERLvcwqs----ahghASALQK---ECYHYLLQAAGYFCLVkdis 178  Trypanosoma br...
XP_001707973 101 -----GEAt-SFLEPLMIDVVNILYNLGVLLARQAS---------------SPDQKE---NVLSLFAQAANLFEKA---- 152  Giardia lambli...

2XS1_A       170 -------------------------------KETV--LSALsr--epTV-----DISPDTVGTLSLIML--AQAQEVFFL 207  human
NP_001096412 158 -------------------------------KENH--IPKLitpvekGR-----DLETRVIDAYTVQCQ--AEAQEVTIA 197  western clawed...
XP_002717538 158 -------------------------------KESH--IPKLitpaekGR-----DLEARLIDAYVIQCQ--AEAQEVTIA 197  rabbit
CAG12984     158 -------------------------------KDVH--IPRLitpaekGR-----DLEPRVMDAYIIQSQ--AEAQEVTIA 197  spotted green ...
NP_505261    168 -------------------------------KDESsrLSGAne--veGS-----DFDPKVMETYILTAT--AEAQEVIVA 207  nematode
XP_002132176 199 -------------------------------DNQA--GKLKnpp-qkCS-----DLDPNVLECYIMCCQ--AEAQEVTIA 237  Ciona intestin...
XP_642244    247 lnlsssskkeeedkkeektesgedekdgggdDDVV--DDNAgki-lkGSdksstDFNDVLLRSLYLQCI--GQAQELTIG 321  Dictyostelium ...
XP_001466254 187 -------------------------------KKHE--IGVAqvs-vpL------DVDKDMAVFLESLAL--SQAQEIGVS 224  Leishmania inf...
XP_843818    179 ----------------------------ddmELYV--VGDVrla-rpG------DVSASVLEFCHLVAI--GQAQEIGSA 219  Trypanosoma br...
XP_001707973 153 -------------------------------SEIV--SEIQp-----LA-----DSSGCDFVDRNYLMAilHTVRGCGYE 189  Giardia lambli...

2XS1_A       208 KATRD--KMK--DAII-AKLANQ-------AADYFGDAFKQCQ--------YKDTLPKEVFPVLAAKHCIMQANAEYHQS 267  human
NP_001096412 198 RAI----ELKhnPGLI-AALAYE-------TANYYQKVDHTLAtl----dpVYI---AKWRSYTQLKMCFYMAYSYCYHG 258  western clawed...
XP_002717538 198 RAI----ELKhaPGLI-AALAYE-------TANFYQKADHTLSsl----epAYS---AKWRKYLHLKMCFYTAYAYCYHG 258  rabbit
CAG12984     198 RAI----ELKhsANII-ASLAFE-------TANFYQKADHTLNtl----epEYS---SKWRKYLQLKQHFYMAYAYCYHG 258  spotted green ...
NP_505261    208 RAI----EMKhdDGLI-SSLAAV-------TASIFSKADQCLNn-------LPDESFARWRRYLQLKHHFYLAYAFAFLG 268  nematode
XP_002132176 238 RAV----EKKhkDSLI-AALANE-------TSKYFQQADHMLnsk---dqiIVG----KWRKYLQLKEKFYKSYALCYYG 298  Ciona intestin...
XP_642244    322 R------AYKknTIQPiVKLAVD-------TANIYKEAMDMLishfteeklVENRLe-KFVNFLQYKVSLYQSLAWNQQA 387  Dictyostelium ...
XP_001466254 225 KAFNA--DPKesTETT-ARLSHQ-------LFLMYETVCTNArtin-trneTFV----EISTLAVVKRDIFHALAFQHAA 289  Leishmania inf...
XP_843818    220 RSTEN--GQSegKMLT-VGLLHQ-------TFKIYEEAHKVGlncvavdhnIFN----EVLTFVKLKVDVFKSLTYSYAS 285  Trypanosoma br...
XP_001707973 190 SEVSRyvAAKgaPALI-AQEAAKahrnfthATEFFDKLSEATd-------vYYG----LW-YTALFKKHYYEVVARYHIS 256  Giardia lambli...

2XS1_A       268 ILAKQQYYFGEE---IARLQHAAELIKT---------------V----ASRYDEYvnvkdFS--DKINRALAAAKKDNDF 323  human
NP_001096412 259 QTLLSADKCGEA---IRSLQEAEKFYGKaealckeygetkgpgT----TAKPSGHlffrkMG--TLVRNTLEKCQRENGF 329  western clawed...
XP_002717538 259 QTLLASDKCGEA---IRSLQEAEKFYAKaealckeygetkgpgP----TVKPSGHlffrkLG--NLVKNTLEKCQRENGF 329  rabbit
CAG12984     259 QTLLAGDKCGEA---IRSLQEAEKCYSRaeelckeyrqtkgpgT----TAKPSEQqf--fLKlgGLIRNTLDKCQRENGF 329  spotted green ...
NP_505261    269 QKQLSEDKCGEA---VRACKQGIAEYGVakemaamyatatgpgT----RIKPEQHlffrrIE--PLLNRHLEKAERENGF 339  nematode
XP_002132176 299 SGLLSDEKCGDS---VRCLMDSNQAFEEtdklckeyittkgagS----TIRPHEHafyrnFQ--KDLQRKLKKSESENGF 369  Ciona intestin...
XP_642244    388 FQQNATHKYGES---IATCKKAQHQLKQtlflirpcvsitltqQ------SLQKPtq--qLQ--PIIDATLARLERENVL 454  Dictyostelium ...
XP_001466254 290 SHLFNNNPGAG----ITLLSQGVEHARIvedyftk-sqngklkL------PFNGTrfvglCS--TTVRNNTERLNKINSL 356  Leishmania inf...
XP_843818    286 SGLFDSNPAAGL-----WLASQSDLLAAnaitekr-asglqkkKlpfrGDELVDDcr-------iFVQRNIERCRKINSL 352  Trypanosoma br...
XP_001707973 257 QYSTPDNALKEIaeaVSLLE----------------------------GLKERLSaleslPS--YGDAQKSYEDIKKLVG 306  Giardia lambli...

2XS1_A       324 IYHDRVPDLkdld-pigkATLVKSTPVNVPIsqKFTDLFEKMVPvsvqqslaa--ynqrkadlVNR 386  human
NP_001096412 330 IYFQKVPPEapqlelkanYGLVEPVPF------EFPAMTSQWSPethtgfdltkrpkddsakpkke 389  western clawed frog
XP_002717538 330 IYFQKIPAEapqlelkanYGLVEPVPF------EFPPASTQWTPetlaafdltkrpkddsakpKPE 389  rabbit
CAG12984     330 IYFHKVPAEapllelkasYGLVEPVAF------ELPPLSEQCTPqvyatfdltkgakndkakpKEE 389  spotted green pufferfish
NP_505261    340 IYHQKVPDEipqldveatYGLAKLDSFTYPppaeswntavysafdlskanmpdfskikkskskldp 405  nematode
XP_002132176 370 IYHHKIPPVapnmslqatHGLVEPTPYTVP---FLSSSWTKAVyagfsiskn---vaqnkkskVKT 429  Ciona intestinalis
XP_642244    455 IGYEVVPSIddis----------------elptEGTRL-AKLRPfiip-----------qvhqSWS 492  Dictyostelium discoideum AX4
XP_001466254 357 VYRAK-PDA---------TKASLPPPQPLA---MRPDIS---LPfrleasp-----sactvalLSR 401  Leishmania infantum JPCM5
XP_843818    353 VHRTNATEDsfel--pppTVLAQKKDI------RLPAAF----P--------------------HQ 386  Trypanosoma brucei TREU927
XP_001707973 307 TGGKKKPSAaaqlqeidkLGVCLSDKTEYTY--ELPSVY---IPsagrv----------mseySDA 357  Giardia lamblia ATCC 50803