3OGD


Conserved Protein Domain Family
AlkA_N

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smart01009: AlkA_N 
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AlkA N-terminal domain
This domain is found at the N terminus of bacterial AlkA . AlkA (3-methyladenine-DNA glycosylase II) is a base excision repair glycosylase from Escherichia coli. It removes a variety of alkylated bases from DNA, primarily by removing alkylation damage from duplex and single stranded DNA. AlkA flips a 1-azaribose abasic nucleotide out of DNA. This produces a 66 degrees bend in the DNA and a marked widening of the minor groove.
Statistics
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PSSM-Id: 214972
Aligned: 69 rows
Threshold Bit Score: 79.9294
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3OGD_A        13 WQPPYDWSWMLGFLAARAVSSVETVA-DSYYARSLAVGEYR----GVVTAIP------DI--A-RHTLHIN-LSAGLEPV 77  Escherichia col...
YP_001187383  10 YQPPWDWQQFHSHFALRAIPGLEALS-ADSYSRGFCIDGAP----GWLRVAP------LP--G-QNALELR-CRIASPAH 74  Pseudomonas men...
YP_001348939  14 YQSPWEWRQFHQHFALRLLAGVENLG-EGHYARSFRADGRG----AWFEVRP------LA--E-RQALALT-LSPAARPL 78  Pseudomonas aer...
YP_001172921   9 YLEPWDWQQFHRHFALRLLPGVERLD-LRGYARTLRLGDAR----GWLGVSA------AD--D-RPALELT-LSDSLRHA 73  Pseudomonas stu...
YP_435772    204 YRPPYAWDALLSFLSARTIAGVDAVV-DGRYHRIVRVEAGEdsavGWFEASH------EA--D-AARIRIR-LDSTLSRH 272 Hahella chejuen...
YP_702291      7 YRGPFTHAPLWRALRAHTVSGLERHDpDGTHTRVVNGPHGP----ALVSVVV------RP--A-DGYVEAH-LTPADPGD 72  Rhodococcus sp....
YP_001222814  17 VPGPFDGGGVIRFLSWHAVTGAEEGD-ATSFTQSARLAHGA----GTVTVRLleaepgDV--G-GARVEVT-TRVEHAAD 87  Clavibacter mic...
YP_001364052  12 VRGELAADPLRRWLRAHALPGAERHL-DGVHERVV--PTGA----GPVEVSV------DL--GtSPGCEQV-VLHAPAAA 75  Kineococcus rad...
YP_411908     13 FRP----GDILAFHRRDRQEIAERVN-HASVQKAMIWCGAP----AYLSISF------EP--G-LAKASLV-IDGKIAED 73  Nitrosospira mu...
YP_633372    187 tRAPFHLEATVRVLQRRPTNLVDVWE-GGRYLRALTVSDGF----VLVEVSN------QGtvD-EPQVRFRvLDGDDSRG 254 Myxococcus xant...
3OGD_A        78 AAEC-LAKM-SRLFDLQCNPQIVNG------ALGRLGaaRPGLRLPGCVD 119 Escherichia coli K12
YP_001187383  75 LDPL-EQRV-RRMFDLDSEPETIARhlsadeLLAPLLlrNPGLRLPVAFD 122 Pseudomonas mendocina ymp
YP_001348939  79 AREL-EARV-RRMFDLDSDPEAIARhfagdpLLGPLVaaNPGLRLPVAFD 126 Pseudomonas aeruginosa PA7
YP_001172921  74 SQPL-VARV-RKMFDLDADPQVIAAhfagdpALGPLVsaQPGLRLPAAYD 121 Pseudomonas stutzeri A1501
YP_435772    273 IGYL-INRL-RAFFDVSCVPQEINk------VLGTLAqnEPGMRIPSGMD 314 Hahella chejuensis KCTC 2396
YP_702291     73 VEAV-TAAV-RRWLDLDTDPLPIDAalshhpQLAPLValRPGLRRLGSVD 120 Rhodococcus sp. RHA1
YP_001222814  88 AAEL-LAGT-RRLLGLDVDAARIDAdlardpALAAVVraTPGLRIPGTLD 135 Clavibacter michiganensis subsp. michiganensi...
YP_001364052  76 LDEV-EGTV-RRWLGLDADPAEAEAwlardpLLAPLVaaRPGLRVPRAVa 123 Kineococcus radiotolerans SRS30216
YP_411908     74 RQPIfEGMV-RRMLGLTQEIEIFEEryrdhpQLGILIaqQPGLRVPVTAT 122 Nitrosospira multiformis ATCC 25196
YP_633372    255 AHAE-ISRVlRRGLGLDVDPEPLDRllqserKLGPIVraLRGMRPPRFPS 303 Myxococcus xanthus DK 1622
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