3RGG,1O4V,3OPQ,3LP6,2NSH,2H31


Conserved Protein Domain Family
AIRC
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smart01001: AIRC 
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AIR carboxylase
Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyse the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.
Links
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Statistics
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PSSM-Id: 214965
Aligned: 251 rows
Threshold Bit Score: 101.069
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RGG_A         3 PLVIILMGSSSDMGHAEKIASELKTFGIE----YAIRIGSAHKTAEHVVSMLKEYEAlDRPKLYITIAGRSNALSGFVDG 78  Treponema denti...
YP_001404892 126 GVVAIITAGTSDIRVAEEAKVIAEEMGCTvrtaYDVGAAGIHR----LFPALKPLL---DADAFIVCAGREGTLPAVVAG 198 Candidatus Meth...
YP_504327    126 GVVGIITAGTSDIRVAEEARIIAEEMGCEvrraYDVGVAGIHR----LFPVIREME---GCHAFVVAAGREGTLPSVVAG 198 Methanospirillu...
YP_844009    122 GKVGILSAGTADIPVAEEARVTAEAMGCEvlteYDVGVAGIHR----LFPAMKRMA---GVDAMVVAAGREGTLPAVVAG 194 Methanosaeta th...
NP_868286    139 THVAVVTAGSTDAHVAEEAAETLAWMGVAceriDDIGVAG----PQRLLAAVPRLR---AAAAIVVVAGMEGALPAALAG 211 Rhodopirellula ...
YP_001245358 116 GTVGVITAGTSDVPFAEETSLILEELGATvrkvYDAGVAGIHR----SFYALKQV---KDADLIMVFAGMEGILPSLVAS 188 Thermotoga petr...
NP_894191     88 GEVVVLSGGSSDLPIAAEAALALRWHGIQsellLDVGVAGLQRLLDQLVR------L-QRAKVLIACAGMEGSLPTVLTG 160 Prochlorococcus...
YP_377508     86 PEVAVISGGSSDRTVVSEATLALQCHGIGvdtvMDVGVAGLHRLLDQLPR------L-QTARVLIACAGMEGALPTVITG 158 Synechococcus s...
NP_875743     88 GEVLVVSGGTSDVGVAAEAELSLRMHGIQtdclMDIGVAGLHRLLGKLERFTK-------ARVVIVCAGMEGSLPTVIAG 160 Prochlorococcus...
YP_397868     87 KKVAIISGGSSDLPVTLEAQLALEIYGVNcqsfIDVGVAGLHR----LISQLEEIN---KYDVLIVCAGMEGALATVVGG 159 Prochlorococcus...

3RGG_A        79 FVKGATIACPPPSDsfa-gadIYSSLRMPSGISpaLVL----EPKnaallaarifslydkeiADSVKSYMESNAQKI 150 Treponema denticola
YP_001404892 199 LVDKPVLGVPVSTGygymgqgRAALASMLQSCSviAVvn-idAGF-----------------TAGAFAARIANGGGK 257 Candidatus Methano...
YP_504327    199 LVDRPVIGVPVSTGygymgagQAALASMLQSCSvlTVvn-idAGF-----------------VAGASAAMIANLVAG 257 Methanospirillum h...
YP_844009    195 LTDAPVIGLPVSTGygaggngIAALLSMLQSCSv-LVVvnidAGF-----------------VAGAFAARIANRIAR 253 Methanosaeta therm...
NP_868286    212 HVATPVIAVPASTGyganfagLTPLMGMLTSCAanVAVvnidAGF-----------------KGGYFAGLIASGIAN 271 Rhodopirellula bal...
YP_001245358 189 LTDLPVIAVPTPIGyghggegTGALTTMLQTCVpgLLVvnigNTV-----------------GAAAAAVRILRRIGS 248 Thermotoga petroph...
NP_894191    161 LVPQPVIGVPVSVGygvsaggRTALEGMLASCApgLVVvnidNGY-----------------GAAMAALRILKAAIT 220 Prochlorococcus ma...
YP_377508    159 LVPQPVIGVPVSVGygisqggRTALEGMLASCApgLLVtnidNGY-----------------GAAMAALRILRGDAE 218 Synechococcus sp. ...
NP_875743    161 LIPQPVIGLPVSVGygvsgggNASLLSMLSSCSpgLLVvnidNGY-----------------GAAMAALRIIKSDLF 220 Prochlorococcus ma...
YP_397868    160 LLAQPIIAVPVSVGygvskngETALNSMLSSCSpgVAVmnidNGY-----------------GAAMAALRII---KS 216 Prochlorococcus ma...
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