2PFM,1C3C,1Q5N,3C8T,2VD6


Conserved Protein Domain Family
ADSL_C
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smart00998: ADSL_C 
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Adenylosuccinate lyase C-terminus
Adenylosuccinate lyase catalyses two steps in the synthesis of purine nucleotides: the conversion of succinylaminoimidazole-carboxamide ribotide into aminoimidazole-carboxamide ribotide (the fifth step of de novo IMP biosynthesis); the formation of adenosine monophosphate (AMP) from adenylosuccinate (the final step in the synthesis of AMP from IMP). This entry represents the C-terminal, seven alpha-helical, domain of adenylosuccinate lyase.
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Statistics
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PSSM-Id: 198066
Aligned: 226 rows
Threshold Bit Score: 43.9775
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2PFM_A       360 YGLIYSQRVMLTLI------DKGMVREEAYDIVQPKAMEAWETQVQFKELVEADERITSKLTQEEINECFNYEHHMQHVD 433 anthrax
YP_644353    360 eGLILAENVTT-LA------AERLGRLEAHELVEAACRRVAEGGGTLREEILAEPRLREALSEEEIEGALDPARYLGAAD 432 Rubrobacter xyl...
YP_001105711 353 RGLVMAESAAAALT-------PSLGRNDAQDLVGRLCRQSVERGTTLRDELLDDPRVRGVLSRDDVLGATDPSAYLGSAT 425 Saccharopolyspo...
YP_001901801 420 GGVLYAEAAVFALA------RQ-LGKSQAHTLVEHAVARAQSAGRHLREELADDPHVQAMLSPAQLEAIFAPDSWRGMAS 492 Xanthomonas cam...
NP_822881    367 qGLIVSERLAAELA-------PVLGRARAKELVTRAAKLAVAENRPLVDVLGEEQE----LTDLDLADLTDPTRYTGSAG 435 Streptomyces av...
YP_362114    375 GGLLYAEAAVFALA-------PHLGKPQAHALVEQAALRAQAQQRHLREVLGEHAQVSAVLTHAQLQAVFDSASWRGMSS 447 Xanthomonas cam...
NP_630771    376 HGLIVSERLSAELA-------PVLGRARARELLTELAARAYAEDRNLGELLAEVPELRGL----DLAGPTDPARYTGAAA 444 Streptomyces co...
ABD14382     370 GGLLLAERVTGALS------ART---DNARALVTAAC----ETGHP----LDEDPGLLEYLQADEIRALLDPAGYLGHAH 432 Rhodococcus sp....
YP_833551    379 GPLLLSEGVSAAVAplleerDGRTGKQQLQDVVDRTLQAPPAEQSGTYRRLLREAVPASALSDEQLEELLDPASYLGQAG 458 Arthrobacter sp...
YP_821542    364 KGAIFAERAVLLLT-------PELGREVARRQVEDAIRETG--------------------SPPDLPGLRDPEQYLGSAE 416 Solibacter usit...

2PFM_A       434 TIFERLG 440 anthrax
YP_644353    433 EFVDRAL 439 Rubrobacter xylanophilus DSM 9941
YP_001105711 426 AFVDRAL 432 Saccharopolyspora erythraea NRRL 2338
YP_001901801 493 VWIDRVL 499 Xanthomonas campestris pv. campestris str. B100
NP_822881    436 ALTDRAL 442 Streptomyces avermitilis MA-4680
YP_362114    448 VWIDRVL 454 Xanthomonas campestris pv. vesicatoria str. 85-10
NP_630771    445 TLTDRAL 451 Streptomyces coelicolor A3(2)
ABD14382     433 DIVDRAL 439 Rhodococcus sp. DK17
YP_833551    459 EISRRIL 465 Arthrobacter sp. FB24
YP_821542    417 AFRKRQM 423 Solibacter usitatus Ellin6076
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