1Z09,1J3W,3LEQ,3KYE,1SZV


Conserved Protein Domain Family
Robl_LC7
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smart00960: Robl_LC7 
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Roadblock/LC7 domain
This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.
Links
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Statistics
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PSSM-Id: 214939
Aligned: 153 rows
Threshold Bit Score: 31.7787
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1Z09_A         4 VEETLKRLQSQKGVQGIIVVN-T-E-GIPIKSTMD----NP----------------------------------T---- 38  human
XP_001522400  28 LEETLGRLSKKAGVKATIVLD-R-StGAILKISGD----FTqirpskaagenvgtsqtdsfpkevtsatanseasDg--- 98  Magnaporthe gri...
EGK97229       3 IDHCFERIRQVRLVKQVIVMN-E-N-GHPIRSTIE----NT----------------------------------Ed--- 38  Anopheles gambi...
ABK56984      32 VQMTFDRLVQLPGVTGAILID-G-N-GVPVRTNLP----AN----------------------------------V---- 66  fruit fly
XP_388775     13 LEEKLGRLSKKPGVKASIVLD-R-AtGAILKTSGQ----VD----------------------------------Alqts 52  Gibberella zeae...
XP_847525     18 VEEVLLRIAKHEGVVGYLVLNpA-D-GRVMRYSGF----SS----------------------------------Der-- 55  Trypanosoma bru...
XP_829711      6 VESVLELITYTKGVAGAVVCN-R-N-GEPIRDSFQ-----D----------------------------------Ld--- 40  Trypanosoma bru...
NP_612110     16 NTDNTNRIT--EQAQGFVVSE-NaG-DSLLHTSFDl---TT----------------------------------Aq--- 51  fruit fly
XP_759247     46 IEATLTRLSSHQGVLGCLVLS-RhD-GLVIRSGGQmfdpSG----------------------------------Pgakq 89  Ustilago maydis...
XP_001467641  18 VEDTLNRIAHHKGVLGYFIME-PqK-GKLLSFAGfr--gSS----------------------------------Reahr 59  Leishmania infa...

1Z09_A        39 -------------------------TTQYASLMHSFILKARSTVRDI-DpQ-ND-LTFLRIRSKKNEIMVAPD--K--DY 86  human
XP_001522400  99 -------------------------AEQLAAMVWAFIGAAGTLVEDL-DtE-DE-LRLLRLRTKKQELVIVPD--P--KY 146 Magnaporthe gri...
EGK97229      39 -------------------------AITAAGLYASLKDKACYNLKSI-D-AdDE-FVMLRIKTRNNEAIISTD--P--EH 86  Anopheles gambi...
ABK56984      67 -------------------------ARIYADRMRPLVILARSMVQDLeN-G-DE-LSYVRLRTRRQETMVATE--N--EH 114 fruit fly
XP_388775     53 ksrttstattfsnetpaleenetqgVEQFAAIVWNYVNSSGNLVQELdG-E-DE-VKLLRLRTRKQELVIVPD--P--KY 125 Gibberella zeae...
XP_847525     56 ------------------------kVKKYADKINGFTALAASTIRTI-DwK-DD-LTFLRMGLGLTEILIAPDvnK--QY 106 Trypanosoma bru...
XP_829711     41 -------------------------RNRAVAYSNMAADLARDAALLF-S-A-DEsLDAVRVRSLNNEIIIKCH--E--EF 88  Trypanosoma bru...
NP_612110     52 --------------------------SIVKHLHASFLKLAQSCVRDL-DtD-DK-LCFLRVKTRKHEFLVSPE--Ea--F 98  fruit fly
XP_759247     90 ---------------------raelLKSVTRLVKSSVESLARDIKAI-DdS-DE-LGFLRVRTKKYEIMITPN--D--KY 141 Ustilago maydis...
XP_001467641  60 ---------------------yadtLKGFIDLTTS-------TVRTI-DwK-EE-MTFLRISCDTVDILVAPD--AnkEY 106 Leishmania infa...

1Z09_A        87 FLIVI 91  human
XP_001522400 147 LLIVI 151 Magnaporthe grisea 70-15
EGK97229      87 GLMYI 91  Anopheles gambiae str. PEST
ABK56984     115 TIILI 119 fruit fly
XP_388775    126 LLVVV 130 Gibberella zeae PH-1
XP_847525    107 VLIVV 111 Trypanosoma brucei TREU927
XP_829711     89 LLVVI 93  Trypanosoma brucei TREU927
NP_612110     99 TVTVV 103 fruit fly
XP_759247    142 LLVVL 146 Ustilago maydis 521
XP_001467641 107 TMVVV 111 Leishmania infantum JPCM5
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