1TF2,2IPC,1NKT


Conserved Protein Domain Family
SecA_DEAD
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smart00957: SecA_DEAD 
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SecA DEAD-like domain
SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Links
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Statistics
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PSSM-Id: 214937
Aligned: 216 rows
Threshold Bit Score: 370.601
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1TF2_A         8 LNKMF-DPTKR--T---LNRYEKIANDIDAIRGDYENLSDD-------ALKHKTIEFKERLEKGATTD--------DL-- 64  Bacillus subtilis
YP_001321557   8 VSKRFeNFKNK--EvydIELYKKTVEEINNI--NYKNASDT-------ELREISENLKNKVKEGIPLD--------EV-- 66  Alkaliphilus me...
YP_001158973  83 rRFLQrPGTTV--D---LAPLEKLLPAIESRMEELQALDDV-------ELTEAAGR-----AEG---------------- 129 Salinispora tro...
Q8FTJ6         7 FWKALgGKQGR--N---QKRSLAIVDQAEAHTRDLEALDDA-------HLAARARTL---VGDGTPQD------------ 59  Corynebacterium...
YP_411619     36 sslgqarlwashlR---LKRLRSFADKVVHRSNALSALSEA-------ELAACVDDLRVKLARQGLTE--------DL-- 95  Nitrosospira mu...
YP_250684      6 FWKAMgSSPKK--N---QKKSRAVVAQADS--SRYSGLSDA-------ELRDAASDVV--TEQSTSEDghhfggqvDD-- 67  Corynebacterium...
NP_939560      7 FWDAMgGKNTR--N---QTKSKNIVAQAAKRGVQFASLSDA-------DVVARAHECAQH-----SDD--------ES-- 59  Corynebacterium...
ZP_06513293   46 FWRLLgASTEK--N---RSRSLADVTASAEYDKEAADLSDE-------KLRKAAGLL--------NLD--------DLae 97  Mycobacterium t...
YP_866082     25 rmgervrlawmrhkqvngwvLGRMAKRVLKAQTERESMTPE-------ALREDLQRLTLALRRDGLED--------AL-- 87  Magnetococcus s...
YP_866104     21 LHGLHgRWRGRaaH---RRRLMQLAEQAERRCMALLGLPETqlqqqllEIQSR---FRRRL---LTDD--------ET-- 81  Magnetococcus s...

1TF2_A        65 ---LVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKG-VHVVTVNEYLASRD 140 Bacillus subtilis
YP_001321557  67 ---LIQAFTLVKEVAGRVVGMTPYDVQKMAAIALHQGKVVEMQTGEGKTLSAVMPAYLNALSGKG-VHILTFNDYLAERD 142 Alkaliphilus me...
YP_001158973 130 ---YAEICAVGREAARRGLDQRPYDVQLLGAMALLSGKVAEMATGEGKTLTATVAAYGHVRLGNGpVHVLTVNDYLARRD 206 Salinispora tro...
Q8FTJ6        60 ---PAELLAVLGIAAHRTLGMRPFPVQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLQGKT-VHSITINDYLAVRD 135 Corynebacterium...
YP_411619     96 ---TIEVFSLVREVCGRKLGLRHFPVQLIGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLP-VHVITVNEYLVRRD 171 Nitrosospira mu...
YP_250684     68 ---APALLAILREAASRTLNMEPFDVQMQGTYRLLHGDVVEMATGEGKTLAGAMAAVGFALQGKR-VHVITVNSYLAGRD 143 Corynebacterium...
NP_939560     60 ---RADLLALLSIGAQRSLSMNPFNVQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGKR-VHSITVNDYLAERD 135 Corynebacterium...
ZP_06513293   98 sadIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRH-VHVVTINDYLARRD 176 Mycobacterium t...
YP_866082     88 ---VEQAFAHVRLTAQRVLGMAHFPVQLKGGYIMLMGYLAEMDTGEGKTLTATLPAATAALAGFT-VHVVTVNEYLARRD 163 Magnetococcus s...
YP_866104     82 ---LLAGVALVGELAWRAVQKRPYRVQFMGALAMHRGWLAEMATGEGKTLTVAVAAVLAGWSGRA-CHVISANDYLTERD 157 Magnetococcus s...

1TF2_A       141 AEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDN-----------M---------------VL 194 Bacillus subtilis
YP_001321557 143 FRWMGPIYKFLGLSCGFVKENMNLEERRKAYLKDITYVTARESGFDYLRDF-----------L---------------CT 196 Alkaliphilus me...
YP_001158973 207 AQWMKPVYDLLGLTVGWVNEGSTPEQRRAAYACDVTYVSVSEAGFDYLRDQ-----------L---------------VT 260 Salinispora tro...
Q8FTJ6       136 AEWMRPLVEFFGLSVGAISETMTPEQRREAYRCDVVYGSVSEIGFDVLRDQ-----------L---------------IT 189 Corynebacterium...
YP_411619    172 ARFMRPVYEFFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDR-----------IdsnrdvsdarravarLF 240 Nitrosospira mu...
YP_250684    144 NDWMGPMFDFFGLTHGAIREDLTADQRRDIYSRDVIFGAINELGFDVLRDQ-----------L---------------IT 197 Corynebacterium...
NP_939560    136 AEWMGDLVRYFGLTVSAVTESLNTEQRRRAYASSIVYAPVTEIGFDVLRDQ-----------L---------------VT 189 Corynebacterium...
ZP_06513293  177 AEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQ-----------L---------------VT 230 Mycobacterium t...
YP_866082    164 AQLMTPLYRALGVTTGVVTESMDSDEKQLGYRANVVYCTSKTLVFDYLRDRiqlgermkpmaM---------------AF 228 Magnetococcus s...
YP_866104    158 AQQMTPLYEACGVTVASGGGALSPEERQLCYKADVVYVTAKTLLADYLRDQ-----------L---------------AT 211 Magnetococcus s...

1TF2_A       195 Y------K-EQ---MVQ--------------------RPLHFAVIDEVDSILIDEARTPLIISGQAAK--S-TKLYVQAN 241 Bacillus subtilis
YP_001321557 197 E------V-KD---LVH--------------------RPFNYAILDEADSILIDEARIPLVIAGNVSEe-G-FN-YDHLI 243 Alkaliphilus me...
YP_001158973 261 D------T-ED---RAQ--------------------PALRTAIVDEADSILIDEARVPMVLAGAVPGe-Q--DPVHTAA 307 Salinispora tro...
Q8FTJ6       190 R------R-AD---AVQ--------------------RRADVAIIDEADSVLVDEALVPLVLAGNQPGh----APRGKIT 235 Corynebacterium...
YP_411619    241 R------G-DEnsrAYL--------------------RGLFFGIVDEADSVLIDEARTPLIISSSVSDk-QgVDDYRRAL 292 Nitrosospira mu...
YP_250684    198 R------R-AD---QVR--------------------TPADVAVIDEADSVMVDEALVPLVLAGSEPGp----APAGRIT 243 Corynebacterium...
NP_939560    190 Q------R-SH---AVQ--------------------NGADVAIVDEADSVLIDEALVPLVLAGNEPG----TAPAGRIT 235 Corynebacterium...
ZP_06513293  231 D------V-ND---LVS--------------------PNPDVALIDEADSVLVDEALVPLVLAGTTHRe-T-PRL--EII 276 Mycobacterium t...
YP_866082    229 DalvgggR-GQ---VML--------------------QGLQYAIVDEADSIFVDEARTPLIISAPSKDa-SeLAFLHTAW 283 Magnetococcus s...
YP_866104    212 R------QgAG---RAQqgfaqwltggaqqpsammlgRGLHTVIIDEADSVLIDEAVTPLILAAPQKIpgM-HGAVMWAA 281 Magnetococcus s...

1TF2_A       242 AFVRTLK--AEK--DYTYDIKTKAVQLTEEGMTKAEKA-FGID-NLFDVKHV-ALNHHINQALKAHVAMQKDVDYVVEDG 314 Bacillus subtilis
YP_001321557 244 EIVRSLK--PNV--DYEIDQHHHNVVLTEKGLIKIEKV-SGCG-NLYASENL-QLLTRLNCVLHAEILLKKEIDYIVRKG 316 Alkaliphilus me...
YP_001158973 308 ALMRGLR--EDr--HYTVAEDGRSVAFTTDGLSAVEAR-LGID--LYDEAQV-AQLSAVNVALHAHALLHRDVDYIVRDG 379 Salinispora tro...
Q8FTJ6       236 EVVRRLK--En--dHYTVSEDRRNVFLTDKGAAALEQA-LGIT-SLYDDEHVgTTLVQVNLALHAQALLIRDIHYIVRDG 309 Corynebacterium...
YP_411619    293 DFCRQLR--DGl--HFRIFAADKLIQLTPAGRDHITNI-CGNLpGVWQVAR--ARFELIEQALAAQLLYMRDKHYIVKDE 365 Nitrosospira mu...
YP_250684    244 DLVKRME--EDK--HFHVSEDHRNVFLTDEGAAFVEKE-LGVD-SLYEDE-G-ELLVQVNVALHAEHLLIRDVHYIVRDG 315 Corynebacterium...
NP_939560    236 EIVRRLK--En--eHYSVDADRRNVSLNDKGAALLEQV-LGIQ-SLYDDAHIgTTLVQVNLALHAQALLIRDVHYIIRDG 309 Corynebacterium...
ZP_06513293  277 RLVAELVgdKDAdeYFATDSDNRNVHLTEHGARKVEKA-LGGI-DLYSEEHVgTTLTEVNVALHAHVLLQRDVHYIVRDD 354 Mycobacterium t...
YP_866082    284 S--LSQQ--LQQgqDYTLSGEE-PPRITEAGSAQLAQL-CVDLpPVWQGQH--RREEAVAQALTAQHSFDRDVHYIIRDD 355 Magnetococcus s...
YP_866104    282 EVAERLH--Ee--eDYTADRRTRQIQLLEGANQLMAAMaWRLD-AVWRSE-V-RRQELVRHALSVRHFIRVGQHYLVQED 354 Magnetococcus s...

1TF2_A       315 QVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFR 385 Bacillus subtilis
YP_001321557 317 KIEIIDEFTGRVADKRHWPDSLHEAVEAKEGLVSETKGRIMGSIALQYFLKLYPKLAGMTGTAISVMNELd 387 Alkaliphilus metalliredi...
YP_001158973 380 TVELIDEMRGRVAQRRRWPDGLQAAVEAKEGLDATAEGEVLGTIAVQAYIGLYPTVCGMTATAVLVGEQLR 450 Salinispora tropica CNB-440
Q8FTJ6       310 KVQLIDASRGRVADLQRWPDGLQAAVEAKEGLAVTEGGRILDTITLQALVGRYPMVCGMTGTAVEATDQLR 380 Corynebacterium efficiens
YP_411619    366 KVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALTDRRKTISRITYQRFFRRYLRLGGMTGTAAEVVGELs 436 Nitrosospira multiformis...
YP_250684    316 KVALIDGSRGRVAELQRWPDGLQAAVEAKEGLDVTDGGRILDQITIQALVGMYPEVCGMTGTALAAGDQLR 386 Corynebacterium jeikeium...
NP_939560    310 KIALIDASKGRVAQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMGRYPIVCGMTGTAVEATDQLR 380 Corynebacterium diphther...
ZP_06513293  355 AVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLR 425 Mycobacterium tuberculos...
YP_866082    356 KVMVVDETTGRVMPDRAWERGLQQLIEIKEGVAVTPPKETLAKISFQLFFRRFLRLSGMSGTCREVGGEia 426 Magnetococcus sp. MC-1
YP_866104    355 KVVLLDDATGRMTPERSLTAGLHQAIEAYEGVPLTDPNASMGQMSFQTFFRRFHRFCGTTGTARESTRELW 425 Magnetococcus sp. MC-1
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