Conserved Protein Domain Family
FIST
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smart00897: FIST 
FIST N domain
The FIST N domain is a novel sensory domain, which is present in signal transduction proteins from Bacteria, Archaea and Eukarya. Chromosomal proximity of FIST-encoding genes to those coding for proteins involved in amino acid metabolism and transport suggest that FIST domains bind small ligands, such as amino acids.
Links
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Statistics
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PSSM-Id: 214894
Aligned: 119 rows
Threshold Bit Score: 59.6336
Created: 14-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
YP_425781      51 LALAFVSPHLDFAEVLEGLR-RLAg-pT-PLIGVSSFGGLCascpggglyrsagpeapGI-------I------LQVFSA 114  Rhodospirillu...
YP_462800      82 AVIVFASASYHLDEVLSGIRaAVGr--V-PIFGASSAGEIC-----------------NG-------TlsesvsVTALAS 134  Syntrophus ac...
YP_528829      33 LILAAHSPAWHCEQIISVISkYn----I-PIVGGIFPQVLL-----------------GD---------------QAYDE 75   Saccharophagu...
YP_660109      32 GIMILCS--EEAASWGDDFKqYVGtldV-PIFGGIFPGLIL-----------------DS-------R---------FEP 75   Pseudoalterom...
YP_001124732   28 FIQVAADDEEQVRHTVELAArRWPs-aH--LVGVAGSLPII-----------------GE-------T------------ 68   Geobacillus t...
YP_266896      33 LLVLTCSQNNYPEEELNAL---FHa-cPlKLFGGIYP--ML-----------------TL-------K------GDLIKQ 76   Colwellia psy...
YP_146551      29 VQIAGNd-EAAVRHAAAALArRWPh-aH--MVGMAGPLPMA-----------------G-------------------EA 68   Geobacillus k...
YP_287071      26 GVLALLPEAEKEQLPLLQSAcSRRg---iALVG-GIFPALI-----------------Erqgf---------skkgAWLL 75   Dechloromonas...
YP_429553      33 ITLVLTTDNYDQERVLSAVKrVIGn--S-RLVGACVPGVIV-----------------NArlykrgvG------ICTVSG 86   Moorella ther...
YP_001210861   33 VLFVFTTSCYKQEEVLAGVLdETGd--V-PLVGACGAGIIT-----------------PAgifnegiA------VLALAG 86   Pelotomaculum...

YP_425781     115 EVIGTVSIQSVFLHNADIRGEQp-SLER------DTrvarigADLAEIALPFALdARDSLALTFVDGLSAC-EN---YLM 183  Rhodospirillu...
YP_462800     135 PFLSVGVGIGKEVSTDWRKAIHa-AIDSgglnryFT------PQDGSYYNSMTLeGRSAFAILFSPASTSHsDSyspEIL 207  Syntrophus ac...
YP_528829      76 GFVVAALNCPLDIVCIN--HLSs-GDES------IA------AQLLNNREKl---IKAKTHITLIDGLAAn-IE---RLV 133  Saccharophagu...
YP_660109      76 RGILVVGLRNNIRVCVIES----------------V------STCAPVSSNMAYmSQSVNSVMILTDALSRqID---GYL 130  Pseudoalterom...
YP_001124732   69 TFLASVMSMAQ---SSVSSLALs-AVDS------AH------PTELAAQIAEAViHEETALLLLFTD--CRaAL---LPL 127  Geobacillus t...
YP_266896      77 GALIIGFKEAVDVTLFAQLNQVt-NE-S------CL------EELITSTLKEKNnFCGQDDFLMFYDALISnIE---GFI 139  Colwellia psy...
YP_146551      69 NLAVGVASMTSSTVSS---LALpaDEFD------RP------DGLAALIAEAVV--RHDTTLLLLFTNHRSaLP---PLL 128  Geobacillus k...
YP_287071      76 YFDQMPPHFLLPAINVEGRPAV---DRL------VS------AALS-GWKSYPAdAPKPTLFMIFDGMLPN-IA---SIL 135  Dechloromonas...
YP_429553      87 EGVEAVTHLQRNISQHSYRKG-----EK------AG------EALLEK-----GgETPGTVLLFPDGFAANiSG---LLR 141  Moorella ther...
YP_001210861   87 DRIKAATAITWFDDGDPWDVG-----KR------LG------KKLLAG-----SrASSGLVAVFPDGLASGiTE---MLQ 141  Pelotomaculum...

YP_425781     184 EAIYESARFpCLFVGGSAAGTLEFRHT--YLFD-GQR-VLEDHAVLV-F-IklaP-GKRYGILKSQNFVKSGVAFSVVEa 256  Rhodospirillu...
YP_462800     208 EELKRLSLGrLLFFGGAAVDAEKTSGHenFIFY-NDQ-VCSDSMILAvF-E---T-TLRFGIAMGHGLHPTAKRARITR- 279  Syntrophus ac...
YP_528829     134 ECMYELMGLnVTAVGGGAGALDFVQRP--CLFT-REG-ALEDAAIIA-G-V---P-S-PIHLGVAHGWEVMDGPYLVTG- 201  Saccharophagu...
YP_660109     131 QHVLAFLPEdCSVFGGGAGTLEFKAQP--CLFS-AAG-MHQDAMILV-E-M-----STHWDLSVGHGWEILAGPFLANS- 198  Pseudoalterom...
YP_001124732  128 LRHLPLANErMTIVGCTLPDG-----C--ALFSrDGR-LDKGVVAVS-F-S---GaSLRVRCFSPFLWEPVGLAFLVTK- 193  Geobacillus t...
YP_266896     140 DCLFEHLDHgINIAGGGAGNLDFIQRH--CIFT-NSG-VHSDAILLV-A-L---P-RT-LNTSVAHGWETFDEPFLVSE- 207  Colwellia psy...
YP_146551     129 RHLP-LANErMVIIGCALPEGS-------VLFS-PDGrLERGGIAVS-FsGt----ALRGHCAAPFLWEPIGLAFSITK- 193  Geobacillus k...
YP_287071     136 DELYLELSNrVEYAGVNAGSETFQPMP--CLFD-ASQ-VVGDGVLAL-Llp----gN--MAPVLEHGFRQPEHAMSATS- 203  Dechloromonas...
YP_429553     142 GLYNVMG-PaFEYIGGGSGDNLRFYRT--YQFT-EEG-ISSDAVAAA-Vir-----gINFQMCLSHGWRPVGEPLMVTK- 209  Moorella ther...
YP_001210861  142 GLYDIMG-PgFKYAGGGTGDNLRFIQT--YQLT-EKC-VASSAVAAA-Iis-----gCVFGISVEHGWKPMGPPLVITR- 209  Pelotomaculum...

YP_425781     257 dADRRTVTSVLDE 269  Rhodospirillum rubrum ATCC 11170
YP_462800     280 -VRDYEVLELDGR 291  Syntrophus aciditrophicus SB
YP_528829     202 -SEQNMLTTLNYT 213  Saccharophagus degradans 2-40
YP_660109     199 -TDDNCVLELNFE 210  Pseudoalteromonas atlantica T6c
YP_001124732  194 -SSDQQIGELDGQ 205  Geobacillus thermodenitrificans NG80-2
YP_266896     208 -AQGQTVQSLNYQ 219  Colwellia psychrerythraea 34H
YP_146551     194 -SRDQQIDELNGQ 205  Geobacillus kaustophilus HTA426
YP_287071     204 -TEGNRIATIDWR 215  Dechloromonas aromatica RCB
YP_429553     210 -AKGRKVYEIDGL 221  Moorella thermoacetica ATCC 39073
YP_001210861  210 -ARGKVVHELDAR 221  Pelotomaculum thermopropionicum SI
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