1Z40_A 7 PWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSnTTFLTPVATGNQY----------LKD 76 Plasmodium falc... ACB87780 109 PWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSnTTFLTPVATGNQY----------LKD 178 malaria parasit... ACM44020 96 PWIKYMQKFDIPRNHGSGIYVDLGGYESVGSKSYRMPVGKCPVVGKIIDLGNG-ADFLDPISSEDPS----------YR- 163 Babesia bovis AAS58045 96 PWIKYMQKFDIPRNHGSGIYVDLGGYESVGSKSYRMPVGKCPVVGKIIDLGNG-ADFLDPISSDDPS----------YR- 163 Babesia bovis XP_670348 1 MGKSICEKYDIEKMHGSGIRVDLGEDARVENRDYRIPSGKCPVIGKGITIQNSeVSFLTPVATGDQS----------VRS 70 Plasmodium berg... XP_729363 54 PWDKYMEKYDIEKVHGSGIRVDLGEDARVENRDYRIPSGKCPVIGKGITIQNSeVSFLKPVATGDKP----------VRS 123 Plasmodium yoel... ABW96965 281 ndKNFVATTALSSL----------EEASQESFP-------CDIYKKKI-------------------------------- 311 Plasmodium chab... XP_766171 249 KWTEFMAKFDIAKVHGSGVYVDLGESATVGIYDYRMPIGKCPVVGKAIILENG-ADFLSSITHHDPKerglgfpatkVAS 327 Theileria parva... XP_954137 246 KWTDFMAKFDIAKVHGSGVYVDLGESATVGSYDYRMPIGKCPVVGKAIILENG-ADFLSSITHHDPKerglgfpatkVAS 324 Theileria annul... XP_001615447 54 PWKAFMEKYDIERTHSSGVRVDLGEDAEVENAKYRIPAGRCPVFGKGIVIENSdVSFLRPVATGDQK----------LKD 123 Plasmodium viva... XP_002364854 77 EMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPdRPPYRNNFLEDVPtekeykqsgnPLP 156 Toxoplasma gond... 2X2Z_A 14 EMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPdRPPYRNNFLEDVPtekeykqsgnPLP 93 Toxoplasma gondii
1Z40_A 77 GGFAFPPTEP-------------------LMSPMTLDEMRHFYKDNkyvkN---LDELTLCSRHAGNMIP--DNDKNSNY 132 Plasmodium falc... ACB87780 179 GGFAFPPTKP-------------------LMSPMTLDDMRLLYKDNe---DvknLDELTLCSRHAGNMNP--DNDKNSNY 234 malaria parasit... ACM44020 164 -GLAFPETAVdsniptqpktrgsssvtaaKLSPVSAKDLRRWGYE---------GNDVANCSEYASNLIP--ASDKTTKY 231 Babesia bovis AAS58045 164 -GLAFPETAVdsniptqpktrgsssasaaKLSPVSAKDLRRWGYE---------GNDVANCSEYASNLIP--ASDRSTKY 231 Babesia bovis XP_670348 71 GGLALPKTDV-------------------HLSPITIDNLKTMYKEHp---VivkLNNMSLCAKHTSFYVP--GYNANSAY 126 Plasmodium berg... XP_729363 124 GGLAFPETDV-------------------HISPITITNLKTMYKDHq---DivnLNDMSLCAKHTSLYVP--GKDATSAY 179 Plasmodium yoel... ABW96965 312 -----------------------------------AEEIKVMNVNR--------------------------NNNGNGTI 330 Plasmodium chab... XP_766171 328 NSSKQDMENQ-------------------LLSPISAQVLRSWNYKHe--------SDLSNCAEYSRNIVP--GSNRNSKY 378 Theileria parva... XP_954137 325 NSSKLDMENQ-------------------LLSPISAQVLRSWNYKHe--------SDLSNCAEYSRNIVP--GSNRNSKY 375 Theileria annul... XP_001615447 124 GGFAFPNAND-------------------HISPMTLANLKERYKDNv---EmmkLNDIALCRTHAASFVM--AGDQNSSY 179 Plasmodium viva... XP_002364854 157 GGFNLNFVTP-------------------SGQRISPFPMELLEKNS----NikaSTDLGRCAEFAFKTVAmdKNNKATKY 213 Toxoplasma gond... 2X2Z_A 94 GGFNLNFVTP-------------------SGQRISPFPMELLEKNS----NikaSTDLGRCAEFAFKTVAmdKNNKATKY 150 Toxoplasma gondii
1Z40_A 133 KYPAVYDDKDKKCHILYIAAQENNGPRYCNKD---ESKRNSMFCFRPAKD-ISFQNYTYLSKNVVDN---WEKVCPRKNL 205 Plasmodium falc... ACB87780 235 KYPAVYDYNDKKCHILYIAAQENNGPRYCNKD---ESKRNSMFCFRPAKD-KSFQNYTYLSKNVVDN---WEEVCPRKNL 307 malaria parasit... ACM44020 232 RYPFVFDSDNQMCYILYSAIQYNQGNRYCDNDgssEEGTSSLLCMKPYKS-AEDAHLYYGSAKVDPD---WEENCPMHPV 307 Babesia bovis AAS58045 232 RYPFVFDSDNQMCYILYSAIQYNQGNRYCDNDgssEDGTSSLLCMKPYKS-AEDAHLYYGSAKVDPD---WEENCPMHPV 307 Babesia bovis XP_670348 127 RHPAVYDKSNSTCYMLYVAAQVNKGPRvllvimqimiinhfvlhpnr--------------------------------- 173 Plasmodium berg... XP_729363 180 RHPVVYDKSNSTCYMLYVAAQENMGPRYCSND---ANNENQPFCFTPEKI-ENYKDLSYLTKNLRDD---WETSCPNKSI 252 Plasmodium yoel... ABW96965 331 QFPRIFISDDK--------------------------------------------------------------------- 341 Plasmodium chab... XP_766171 379 RYPFVYDESEKLCYILYSPMQYNQGVKYCDKDs-aDEGTSSLACMYPDKS-KDDSHLFYGTSGLHMD---WPVVCPVYPI 453 Theileria parva... XP_954137 376 RYPFVYDESEKLCYILYSPMQYNQGVKYCDQDs-pDEGTSSLACMYPDKS-KEDSHLFYGTSGLHMD---WPVVCPVYPI 450 Theileria annul... XP_001615447 180 RHPAVYDEKEKTCHMLYLSAQENMGPRYCSPD---AQNRDAVFCFKPDKN-ESFENLVYLSKNVRND---WDKKCPRKNL 252 Plasmodium viva... XP_002364854 214 RYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKg--EPPDLTWYCFKPRKSvTENHHLIYGSAYVGENpdaFISKCPNQAL 291 Toxoplasma gond... 2X2Z_A 151 RYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKg--EPPDLTWYCFKPRKSvTENHHLIYGSAYVGENpdaFISKCPNQAL 228 Toxoplasma gondii
1Z40_A 206 QNAKFGLW---VDGNCEDIPHVNEFPAIDLFECNKLVFELSAS------------------------------------- 245 Plasmodium falc... ACB87780 308 ENAKFGLW---VDGNCEDIPHVNEFSANDLFECNKLVFELSAS------------------------------------- 347 malaria parasit... ACM44020 308 RDAIFGKWs--GGSCVAIAPAFQEYANSTEDCAAILFDNSATDldidvvneefnelkeltsglkrlnlskvanaifspls 385 Babesia bovis AAS58045 308 RDAIFGKWs--GGSCVAIAPAFQEYANSTEDCAAILFDNSATDlnieavnedfnelkeltdglkrlnmskvanaifspls 385 Babesia bovis XP_670348 -------------------------------------------------------------------------------- Plasmodium berg... XP_729363 253 KNAKFGIW---VDGYCTDYQKHVVHDSDSLLKCNQIIFNESASdqpkqyerhledatkirqgiverngkligeallpigs 329 Plasmodium yoel... ABW96965 -------------------------------------------------------------------------------- Plasmodium chab... XP_766171 454 RDSIFGSYddeKDECVPIDPIFVEDADDYEECAKIIFEYSPSDvdistnnqklsdvdlykeamnngklstalsimfapry 533 Theileria parva... XP_954137 451 RDSIFGSYddqKDECVPIEPIFEEEAEDYEACAKIIFEYSPSDvdistnnqklsdvdlykeamnngklstalsimfapry 530 Theileria annul... XP_001615447 253 GNAKFGLW---VDGNCEEIPYVKEVEAEDLRECNRIVFGASASdqptqyeeemtdyqkiqqgfrqnnremiksaflpvga 329 Plasmodium viva... XP_002364854 292 RGYRFGVWkkgRCLDYTELTDTVIERVESKAQCWVKTFENDGV------------------------------------- 334 Toxoplasma gond... 2X2Z_A 229 RGYRFGVWkkgRCLDYTELTDTVIERVESKAQCWVKTFENDGV------------------------------------- 271 Toxoplasma gondii
1Z40_A -------------------------------------------------------------------------------- Plasmodium falc... ACB87780 -------------------------------------------------------------------------------- malaria parasit... ACM44020 386 nvagtsrisrgvgmnwatydkdsgmcalinetpnclilnagsialtaigspleydavnypchidtngyveprakttnkyl 465 Babesia bovis AAS58045 386 nvagtsrisrgvgmnwatydkdsgmcalinetpnclilnagsialtaigspleydavnypchidtngyveprakntnkyl 465 Babesia bovis XP_670348 -------------------------------------------------------------------------------- Plasmodium berg... XP_729363 330 yksgqikshgkgynwgnydsknnkcyifet---kptclindknfiattalssteefeenfpceiyknkiaeeikvlnlnq 406 Plasmodium yoel... ABW96965 -------------------------------------------------------------------------------- Plasmodium chab... XP_766171 534 sedrpiytkgvginwatysveekkcnildvvptcliisngyyaltslsspneddainypcnivhgkgflknpntgkkkdq 613 Theileria parva... XP_954137 531 sedrpiytkgvginwatysveekkcnildvvpscliisnghyaltslsspneedainypcdivqgkgflknpnggkknaq 610 Theileria annul... XP_001615447 330 fnsdnfkskgrgfnwanfdsvkkkcyifntk--ptclindknfiattalshpqevdlefpcsiykdeiereikkqsrnmn 407 Plasmodium viva... XP_002364854 -------------------------------------------------------------------------------- Toxoplasma gond... 2X2Z_A -------------------------------------------------------------------------------- Toxoplasma gondii
1Z40_A 246 --------------------DQPK 249 Plasmodium falciparum 3D7 ACB87780 348 --------------------DQPK 351 malaria parasite P. falciparum ACM44020 466 dvpfevttalsmktlkcnayvhtk 489 Babesia bovis AAS58045 466 dvpfevttalsmktlkcdayvhtk 489 Babesia bovis XP_670348 ------------------------ Plasmodium berghei strain ANKA XP_729363 407 ntsngnnsikfprifistdkNSLN 430 Plasmodium yoelii yoelii str. 17XNL ABW96965 342 --------------------ESLK 345 Plasmodium chabaudi XP_766171 614 kppeppkdekqnkkeeeskpKEKG 637 Theileria parva strain Muguga XP_954137 611 eppkepepeepkkegaenkpKEKG 634 Theileria annulata strain Ankara XP_001615447 408 lysvdgerivlprifisndkESIK 431 Plasmodium vivax SaI-1 XP_002364854 335 --------------------ASDQ 338 Toxoplasma gondii ME49 2X2Z_A 272 --------------------ASDQ 275 Toxoplasma gondii
Jiyao W et al.(2023). "The conserved domain database in 2023.",