Conserved Protein Domain Family
AGTRAP
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smart00805: AGTRAP 
Angiotensin II, type I receptor-associated protein
This family consists of several angiotensin II, type I receptor-associated protein (AGTRAP) sequences. AGTRAP is known to interact specifically with the C-terminal cytoplasmic region of the angiotensin II type 1 (AT(1)) receptor to regulate different aspects of AT(1) receptor physiology. The function of this family is unclear.
Links
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Statistics
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PSSM-Id: 197883
Aligned: 4 rows
Threshold Bit Score: 216.265
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9WVK0         1 MELPAVNLKVILLVHWLLTTWGCLV--FSSSYAWGNFTILALGVWAVAQRDSIDAIGMFLGGLVATIFLDIIYISIFYSS 78  house mouse
NP_065083      1 MELPAVNLKVILLGHWLLTTWGCIV--FSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPR 78  human
NP_001015751   1 MELPAVNLKAIVFTHWLLTVFACMIdwLPKAYGLANITILAMGVWAIAQRDSIDAIFMFLIGLLLTILTDILLFALYFTE 80  western clawed ...
NP_727668      8 MGSPFVRVKLVAFVHFFFISNAMLGswGHGAYEFYNFLFLIAMFWSMHSKDSVEAIQTALVINASSIFFDIVSISLHF-- 85  fruit fly

Q9WVK0        79 V-------ATGDTGRFGAGMAILSLLLKPFSCCLVYHMHRERGGELPLRPDFFGPSQEHSAYQTIdsssD---AAADPFA 148 house mouse
NP_065083     79 V-------SLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTI----DsaeAPADPFA 147 human
NP_001015751  81 AekasesgPLRDLFRFSSGMGIFSLLLKPLSCFFMYHMYRERGGEYFVNLGFITLSRDRSSYQSI----E----HMDPPA 152 western clawed ...
NP_727668     86 ----------GIMNGWAVAFSIINLILRPVSVALLYKEFNTRGGTLP--TGSVFPTSQQRSYQDI----D---RPTQPTP 146 fruit fly

Q9WVK0       149 SLENKGQAaPRGY 161 house mouse
NP_065083    148 VPEGRSQD-ARGY 159 human
NP_001015751 153 DQDNKLP--SRTY 163 western clawed frog
NP_727668    147 TNSQPGPNvASIF 159 fruit fly
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