Conserved Protein Domain Family
PIG-X

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smart00780: PIG-X 
PIG-X / PBN1
Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.
Statistics
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PSSM-Id: 197872
Aligned: 15 rows
Threshold Bit Score: 227.66
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CBF86444     209 PPTGLHPTMTISIA----P-EalkePPRRPDA-----TCALHAYLTLPSKLFGDKYQLSttdplFLK-----SH-N-LAS 271 Aspergillus nid...
XP_369773    275 TSTGLHPTLRLVMT----S-R----KPDE--G-----SCTPHAYLTLPRTIFADMYQLSdp--lFLA-----SK-N-LTA 329 Magnaporthe gri...
NP_001004985  32 LNKGYHRDLETSVV----V-Q----GPAELVK-----HCRVLIQEHIPSGLYLDPYQLS-----SLR-----HH-N-L-T 84  western clawed ...
XP_504061    278 RPVGLHPKSELKLR----H-Ia--iPTDHNDEndgvkHCRLFAKYSAPSSIFFDKYQLA-----DLErttseHP-NgQGR 344 Yarrowia lipoly...
NP_986281    273 QPVTLHPVIEVDLS----S-V----SASGP-------ACAHHVFLQLPAQLFVDKFQQP--------------------- 315 Ashbya gossypii...
XP_461123    243 KENGMHPFLKTDIH----SdI----PNDEDLI-----QCKLYYYLDLNKSFFVDKYQLP-----KE------------FT 292 Debaryomyces ha...
NP_588484    134 LPVGLHPKLHVHLK----N-L----HKPED-------ECSLQGFMYIPPTLFIDRYELSn---iAEM-----HAdN-LGH 188 Schizosaccharom...
NP_009878    224 EPIGLHPKIMIDLT----D-F-------EERP-----KCMYLMHLQLPLELFIDKFQSS--------------------- 265 Saccharomyces c...
XP_716754    253 iPQGLHPILSTELNtttiV-I----PTDFDVE-----ECKFYYYLNLNKSLIFDQFQNI--------------P-I-GSQ 306 Candida albican...
XP_444992    225 NTNGLHPKMKIDLS----G-I----RKDKD--------CRHFVFSQLPSEIFVDKFQSP--------------------- 266 Candida glabrat...
CBF86444     272 LRAVAGETDLEAPDWSI--SR--WGSNWLLELA-S----PsesDEV-AEEWNITI-PLHLRYLPP-SEsGYQPAS--VPW 337 Aspergillus nid...
XP_369773    330 LRYMSSPVDLEAPDYAM--SI--WGSFVLVDLAqP----S---VDA-GDAWTAEI-PLHLRYLAPaTG-GHRSIE--VPA 393 Magnaporthe gri...
NP_001004985  85 EVLLLTPVDVEAPEYLS--RG--HTALVYTK---P----D---PSC-AHCYTSTV-PLHIRYHRPaSQtDKVSIT--LQN 146 western clawed ...
XP_504061    345 LLALWGEADLEEPRYHT--EG--WGSEALVEIF-PitdaP---EGT-PFNLNFTL-PLHLRYEEPkEGeTYEPNE--APW 412 Yarrowia lipoly...
NP_986281    316 PELLFGEDDLELPEYKV--EA--WGSEVIYALE-P--------------GRVNRV-QLHSRYARPgPGrRYEVVP--LR- 372 Ashbya gossypii...
XP_461123    293 SYVNFGNTDLELPEYKI--NE--WGSEILMEIE-N--------------NQQISL-PLHSRYQLPnNEsSIRVTG--IND 350 Debaryomyces ha...
NP_588484    189 VLGIWGETDLEAPSYKL--NG--TGSFFWFDIY-T----D---DGLlQKDYIDTIiPLHTRYQSPlKGqTYLKTS--LTN 254 Schizosaccharom...
NP_009878    266 PLLLFGEDDLELPEYSLrdKA--WGSESIFELK-A--------------GTMNEV-TLHTRYIEPsNNkG-DKLE--VSF 324 Saccharomyces c...
XP_716754    307 LIINNGNKNLELPEYKI--NQ--WGNELLFEFE-F----D---NDN-DIPHHINL-TVHSRYQLPqNNhSHSQISnvLNS 372 Candida albican...
XP_444992    267 GSIVFGLDDLELPDYKV--NSlsWGSESIVTLK---------------EGQINEI-TYFSRYLEPkERaSNK--T--VGF 324 Candida glabrat...
CBF86444     338 -PVVFWACSAED-GT-Km--GVNPFDR-----INLGWEGLFGPRTMFYQLHPSPSPE------Ggn---lvEELEVPVLT 398 Aspergillus nid...
XP_369773    394 -PAVFWACAADEvGN-L---ATNPFDR-----TRLGYDGLFDVNTVFWHLEPRPPPL------PvgttrlvLGVDVPVLD 457 Magnaporthe gri...
NP_001004985 147 -PKLLLNCGQDF-PP-T---SCSPHSV-----TEAPCDLKDKELCQWLDLPYTADPN------A-------LNLEVPVGL 202 western clawed ...
XP_504061    413 -PLVFWVCAETD-EQ-LanfKQSPFDV-----THNSYMRLFPEGVSYHHIGPREANGrgfpllS-------TSWGTPVAD 477 Yarrowia lipoly...
NP_986281    373 -PYVFEACDTGS-AD-I---AENPFYS-----KGMGFEAYFTADTVFKHRNST----------R-------LNIPVPRGN 424 Ashbya gossypii...
XP_461123    351 -PLIFYGCDVKD-SYlL---ESSPFDNrl--dIGGNYERFFTDNTVFYHLSSHENQ---------------LQINIPRGN 408 Debaryomyces ha...
NP_588484    255 -PKFFWNCDTED-KV-N------------------DFRFLFSSKNKYTLQNDPTT----------------LSISIPIAD 297 Schizosaccharom...
NP_009878    325 dPEVILACDTGD-NK-V---SRNPFYK-----KGLGYESLFTDDTTFRHLNSTT-----------------LLVPIPRPD 377 Saccharomyces c...
XP_716754    373 lPNIFIGCNVKE-GNlL---DKSPFDTkrdvkIGGNYEIYFTEDTVFYHLQNSDNSG------Nsgs-stlLEINIPHGK 441 Candida albican...
XP_444992    325 ePILFKACQVGK-EE-D---LSNPFYS-----RSLGYEAYFSENTKFYHINST----------S-------VHVNIPYPN 377 Candida glabrat...
CBF86444     399 LKEnsgifnSQVIELGTFAVISIGFLW----VLWKLGLV 433 Aspergillus nidulans FGSC A4
XP_369773    458 IER------SGWIGAGTAAVILLGFGW----VVWKLLGa 486 Magnaporthe grisea 70-15
NP_001004985 203 AED------GPIVCAVTLIVTLICAGM----ILGAVYRH 231 western clawed frog
XP_504061    478 IDR------FAAVRDYTSIMMVAGFLMvtiaILRKVFRG 510 Yarrowia lipolytica CLIB122
NP_986281    425 SND------FPSIQYVTVLSILFSVLY----ISYCLFRR 453 Ashbya gossypii ATCC 10895
XP_461123    409 ES-------IKKINFVTNLIFIAGVVL----IFYKIVQG 436 Debaryomyces hansenii CBS767
NP_588484    298 LSY------KHVVEWVTNGVAIFSFFY----LLLYLWKR 326 Schizosaccharomyces pombe 972h-
NP_009878    378 TKD------YSKIKNGTLLCLLISIIY----IFSKVFGN 406 Saccharomyces cerevisiae S288c
XP_716754    442 TT-------FDRVNNITSLGLLIGVLM----ILYAISIR 469 Candida albicans SC5314
XP_444992    378 KND------IGNIEYTTFGIVVLAICY----LIYKLLRP 406 Candida glabrata CBS 138
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