1NMN,3BZC,3PSI


Conserved Protein Domain Family
YqgFc
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smart00732: YqgFc 
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Likely ribonuclease with RNase H fold.
YqgF proteins are likely to function as an alternative to RuvC in most bacteria, and could be the principal holliday junction resolvases in low-GC Gram-positive bacteria. In Spt6p orthologues, the catalytic residues are substituted indicating that they lack enzymatic functions.
Links
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Statistics
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PSSM-Id: 128971
Aligned: 72 rows
Threshold Bit Score: 62.1992
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1NMN_A        3 GTLLAFDFG-TKSIGVAVGQRITGTARPLPAIKA---Q-----DGTPDWN-----IIERLLKEWQPDEIIVGlplnmDGT 68   Escherichia coli
Q9CIS1      308 RVVMGFDPAyRTGAKLAIVDETGKLLMTTVIYPV---KpanagQIAQAKK-----DLAKFIREYGVNMIAIG-----NGT 374  Lactococcus lac...
Q99SI9      315 KQILGVDPAfRTGCKLAVINPFGTFIAKGVIYPH---Ppv--sKKEAAEK-----DFVQMVKAYDVQLIAIG-----NGT 379  Staphylococcus ...
Q9A0W8      309 KMVLGFDPAfRTGAKLAIVDQTGKLLTTQVIYPV---ApasqtKIQAAKE-----TLTQLIETYQIDIIAIG-----NGT 375  Streptococcus p...
Q9PRB6      316 HVVLGFDPGyVHGCKLAIVNKNNQLLHTDIIYPH---Kpq--iLITQAKN-----TLISLINKYEVNTIAIG-----NGT 380  Ureaplasma parvum
O83894      332 TRVLGIDPGiRTGTKCAALDETGQYLGSFVIYPH---------NTDHARA-----ALTQALDRYRIQLVAVG-----NGT 392  Treponema pallidum
ZP_05301262 321 KIILGVDPAfRTGCKFSVLDQTGKVLEIGVVYPHtakA-----RRPEAKQ-----KIAEILSTYQVEVIAIG-----NGT 385  Listeria monocy...
ZP_05713826 322 KVVLGFDPAyRTGCKLAVVDATGKVLAIEVIYPH---K-----PAAQAKReaagpAFIQLINKYQVDMVAIG-----NGT 388  Enterococcus fa...
BAA91577    162 RTLMGVDPGyKHGCKLAIISPTSQILHTDVVYLHc--G-----QGFREAE-----KIKTLLLNFNCSTVVIG-----SGT 224  human
NP_651070   526 eRILGIDPGfINGCKLALISETADVLYTGVIYPHgamS-----NKRAAEQ-----KLVQLLSDHNCKIIGLG-----NGT 590  fruit fly

1NMN_A       69 EQPLTarARKFANRIH----G--RF----GVEVKLHDERLSTVEA 103  Escherichia coli
Q9CIS1      375 ASRES--ESFVAEVLK----EnnFS----DVYYVIVSESGASVYS 409  Lactococcus lactis subsp. lactis
Q99SI9      380 ASRET--EQFVADLIK----Kh-qL----PVQFIIVNEAGASVYS 413  Staphylococcus aureus subsp. aureus Mu50
Q9A0W8      376 ASRES--EAFVADVLK----D--FP----NTSYVIVNESGASVYS 408  Streptococcus pyogenes serotype M1
Q9PRB6      381 ASNES--VIFISDLIK----Ef-KL----NLNYCVISEDGASIYS 414  Ureaplasma parvum
O83894      393 GSHAV--QELIASIIS----Et-HS----AVAFTVVEEDGASVYS 426  Treponema pallidum
ZP_05301262 386 ASRET--EQFIVEVIR----Es-NS----NAYYCIVNEAGASVYS 419  Listeria monocytogenes LO28
ZP_05713826 389 ASRES--ELFVAEQLK----Sa-DH----KTYYAIVNEAGASVYS 422  Enterococcus faecium DO
BAA91577    225 ACRET--EAYFADLIM----K--NYfaplDVVYCIVSEAGASIYS 261  human
NP_651070   591 ACRET--EHWLTGMFHagvlD--SR----IIRYSIVNENGASIYS 627  fruit fly
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