1WMH,2CU1,1WJ6,1WMH,2DYB,1OEY,1Q1O


Conserved Protein Domain Family
PB1
?
smart00666: PB1 
Click on image for an interactive view with Cn3D
PB1 domain
Phox and Bem1p domain, present in many eukaryotic cytoplasmic signalling proteins. The domain adopts a beta-grasp fold, similar to that found in ubiquitin and Ras-binding domains. A motif, variously termed OPR, PC and AID, represents the most conserved region of the majority of PB1 domains, and is necessary for PB1 domain function. This function is the formation of PB1 domain heterodimers, although not all PB1 domain pairs associate.
Links
?
Statistics
?
PSSM-Id: 214770
Aligned: 96 rows
Threshold Bit Score: 49.508
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
1WMH_A         6 QVRVKAYY-RGDI----MI-----THFEP--------SIS----FEGLCNEVRDMCSFdneqLFTM-KWIDEEGDPCTVS 62   human
O96611        15 FIRIKCIL-GDDI----RI-----IKFNS--------NIS----YGGLMNQLEQDFQC----PISIhQYEDYEGDKVTVK 68   Dictyostelium ...
Q9GMZ5       237 TNWLRCYY-YEDT----IS-----TIKDIaveedlksTPL----FKDLLELMRREFQRe---DIAL-NYQDAEGDLVRLL 298  bottlenosed do...
O70145       350 PYMLKVHY--KYT----VV-----METRL--------GLP----YSQLRNMVSKKLALsp-eHTKL-SYRRRDSHELLLL 404  house mouse
Q9D222        18 VIRIKIPNsGAVD----WT-----VHSGP--------QLL----FRDVLDVIGQVLPEa--tTTAF-EYEDEDGDRITVR 73   house mouse
Q92962        18 VIRIKIPNsGAVD----WT-----VHSGP--------QLL----FRDVLDVIGQVLPEa--tTTAF-EYEDEDGDRITVR 73   human
P97369       237 TNWLRCYF-YEDTgktiKD-----IAVEE--------DLSstplFKDLLALMRREFQRe---DIAL-SYQDAEGDLVRLL 298  house mouse
NP_001076123 237 TNWLRCYY-YEDT----VStiikdIAVEE--------DLSstplFKDLLELMRREFQRe---DIAL-NYRDAQGDLVRLL 299  rabbit
NP_001075570 351 PYTLKVHY-K-FT----VL-----LDTQP--------QLP----YSQLRDAVARKLELap-eHTKL-SYRPRAGPELAPL 405  rabbit
NP_776545    352 SYTLKVHY-K-YT----VV-----METQF--------RLP----YSQVRDMVAKKLDLlp-eHTKL-SYRRQDSNELVPL 406  cattle

1WMH_A        63 SQLELEEAFRLYELNk------DSE----LLIHVF 87   human
O96611        69 SKDDIMEALTMYFELkalnptkIIS----TKFFLK 99   Dictyostelium discoideum
Q9GMZ5       299 SDEDVRLMVKWTQGLpsq--khLFP----WKLHIT 327  bottlenosed dolphin
O70145       405 SEESMKDAWGQVK---------NYC----LTLWCE 426  house mouse
Q9D222        74 SDEEMKAMLSYYYS---------TV----MEQQVN 95   house mouse
Q92962        74 SDEEMKAMLSYYYS---------TV----MEQQVN 95   human
P97369       299 SDEDVGLMVKQARGLp------SQKrlfpWKLHVT 327  house mouse
NP_001076123 300 SDEDVGLMVRQARGLp------SQKrlfpWKLHVT 328  rabbit
NP_001075570 406 SEASMADAWSHVDGS---------C----LTLWCE 427  rabbit
NP_776545    407 SEFSMKDAWAQVK---------NYC----LTLWCE 428  cattle
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap