2CPR,2HBJ


Conserved Protein Domain Family
HRDC

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smart00341: HRDC 
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Helicase and RNase D C-terminal
Hypothetical role in nucleic acid binding. Mutations in the HRDC domain cause human disease.
Statistics
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PSSM-Id: 128635
View PSSM: smart00341
Aligned: 26 rows
Threshold Bit Score: 71.1742
Threshold Setting Gi: 75347129
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2CPR_A       28 NTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINeMHLLIQQAREMPLL 107 human
O07183      245 DRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAvWWAALAAARESPDP 324 Mycobacterium tu...
Q17951      489 NTRQDYALTHLFKWRDVVARAEDESPHFVLPNHMMLSLSETLPRDVGGIYACCNPLPYFVKQRTGdILKIIVEARDVKLE 568 Caenorhabditis e...
O69858      214 RRRQLAVVRELWQARDRIAQRRDVSPGKVLGDAAIVEAALALPPNAHALAALNGFGRVNRRQLEQwQLSVDRARALSESQ 293 Streptomyces coe...
Q50004      245 DRRALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFGGANQRRSAAmWLAALETARQSQDL 324 Mycobacterium le...
Q12149      435 PPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKlLANLIRDALRNIKN 514 Saccharomyces ce...
ZP_03067168 210 RTRQLACLQLLADWRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFH-GKtLLALVEKAQTLPED 288 Shigella dysente...
2HBJ_A      309 PPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKlLANLIRDALRNIKN 388 baker's yeast
NP_438552   239 NPLELSRLRVLAQWRQNVAIERDLALSYIVKSEHLWKVAKNNPRNTSEMLEMGLTENEVRVRGKEiLQLLSQARRISSND 318 Haemophilus infl...
NP_220842   207 DENFNRTIQVLAAYREENAQTINIPRKHFILDEDLIKLCKNMPLNYKDFKNLKLKSKYLHKKKYKdEIINLFNNL----- 281 Rickettsia prowa...
2CPR_A      108 K 108 human
O07183      325 P 325 Mycobacterium tuberculosis
Q17951      569 K 569 Caenorhabditis elegans
O69858      294 L 294 Streptomyces coelicolor
Q50004      325 P 325 Mycobacterium leprae
Q12149      515 T 515 Saccharomyces cerevisiae S288c
ZP_03067168 289 A 289 Shigella dysenteriae 1012
2HBJ_A      389 T 389 baker's yeast
NP_438552   319 Y 319 Haemophilus influenzae Rd KW20
NP_220842       -     Rickettsia prowazekii str. Madrid E
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