2GK9


Conserved Protein Domain Family
PIPKc

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smart00330: PIPKc 
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Phosphatidylinositol phosphate kinases
Statistics
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PSSM-Id: 214623
Aligned: 19 rows
Threshold Bit Score: 313.549
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2GK9_A         43 LPDDFKASSKIKVNNHLfH-RENLPSH----FKFKEYCPQVFRNLRD-R-FGIDDQDYLVSLTRNP-P-SE---SEGSDG 110  human
O04095        464 RASDFGKNARTKMFFPR-DgSNFTPPHksvdFSWKDYCPMVFRNLRQ-M-FKLDAAEYMMSICGDD-GlTEissPGKSGS 539  thale cress
O48709        354 RHSDFDPKDKQWTRFPP-EgSKSTPPHlsaeFKWKDYCPIVFRHLRD-L-FAIDQADYMLAICGNE-SlREfasPGKSGS 429  thale cress
O04613          8 ENRIRYSTKHIKHLPPG-Sit---------eFDWKDYCPVGFGLIQE-L-EGIDHDDYLLSICTDE-T-LKkisSGKIGN 73   thale cress
XP_002879915  409 kPSAFDPKDKIWRRFPR-EgTKYTPPHqsteFKWKDYCPLVFRSLRK-L-FKVDPADYMLSICGNDaL-RElssPGKSGS 484  Arabidopsis l...
O23705          7 TAKDVKATEKNRIRYSS-KhIKHLPPGtiteFEWKDYCPLGFRLIQE-L-EDINHDEYMKSICNDE-T-LRklsTSKVGN 81   thale cress
AAD10191     1745 QDEVDGGDTQKKQLTNP-H-VELQFSDanakFYCRLYYAGEFHKMREvI-LGSSEEEFIRSLSHSS-P--WqarGGKSGA 1818 house mouse
NP_510155    1194 SLKFSQMDDGENLASSQ-H-LEVEFEDesasYYVKMLYAEKFRKLRE-LlIAEGEETFIRSLSNST-F--WtpqGGKSGS 1267 nematode
NP_001190899 1425 SQLLHSSLYLKDLHARI-S-FTDEGPPgkvkYSVTCYYAKEFEALRM-I-CCPSETDFIRSLGRCR-K--WgaqGGKSNV 1497 thale cress
NP_596090    1629 gsTQFKIENLMLKPTGT-H-LKYQFEEgsarLSCKVFFAEQFSALR--R-ACGCEETFVTSLARCS---LWessGGKSGS 1700 Schizosacchar...
2GK9_A        111 RFLISYDRTLVIKEVSSEDIADMH-----------------SNLSNYHQYIVKC-HgNTLLPQFLGMYRVS---VDNe-- 167  human
O04095        540 IFYLSHDDRFVIKTLKKSELQVLL-----------------RMLPKYYEHVGDH-E-NTLITKFFGVHRIT---LKWg-- 595  thale cress
O48709        430 AFYLTQDERYMIKTMKKSEIKVLL-----------------KMLPNYYEHVSKY-K-NSLVTKFFGVHCVK---PVGg-- 485  thale cress
O04613         74 VFHISNDNRFLIKILRKSEIKCVYmfhiesfiennlvkvtlEMLPRYYRHINYH-R-SSLFTRIFGAHSVK---PLGgvk 148  thale cress
XP_002879915  485 FFYLTNDDRYMIKTMKKSETKVLL-----------------GMLAAYYNHVRAF-E-NSLVIRFFGLHCVK---LNGpt- 541  Arabidopsis l...
O23705         82 MFLLSKDDRFLIKILRKSEIKVIL-----------------EMLPGYFRHIHKY-R-STLLSKNYGAHSVK---PIGg-- 137  thale cress
AAD10191     1819 AFYATEDDRFILKQMPRLEVQSFLdf--------------aPHYFNYITNAVQQ-KrPTALAKILGVYRIG---YKNsqn 1880 house mouse
NP_510155    1268 FFYRTQDDRFVVKQMSRFEIQSFVkf--------------aPNYFDYLTTSATEsK-LTTLCKVYGVFRIG---YKSktt 1329 nematode
NP_001190899 1498 FFAKSLDDRFIIKQVTKTELESFIkf--------------gPAYFKYLTESIST-KsPTSLAKILGIYQVSskhLKGgk- 1561 thale cress
NP_596090    1701 AFLKTFDKKYILKVLSRLESDSLLnf--------------aPAYFDYISKVFFH-ElPTALTKIFGFYRVD---IRNptt 1762 Schizosacchar...
2GK9_A        168 ------------DSYMLVMRNMFSHRLPVHRKYDLKGSLVSREAs-DK--EKVKELPTLRDMDFLnk--nQKVYIGEEEK 230  human
O04095        596 -----------kKVRFVVMGNMFCTELKIHRRYDLKGSTQGRFT--EK--IKIQEKTTLKDLDLA-----YEFHMDKLLR 655  thale cress
O48709        486 -----------qKTRFIVMGNLFCSEYRIHKRFDLKGSSHGRTI--DKdeGEIDETTTLKDLDLK-----YVFRLETSWF 547  thale cress
O04613        149 vtriiyiyhsiiRTYFAVMSNMLHSTIFVNKLYDLKGSPKGRSN--KK--IEVRNTTVLKDIDFD-----FCFYVDPLAR 219  thale cress
XP_002879915  542 ----------qkKVRFVIMGNLFCSKYSVHRRFDLKGSSLGRTT--DKpeSEIDSNTILKDLDLn-----FIFRLQKAWY 604  Arabidopsis l...
O23705        138 -----------vKTYFVVMSNILQSDVFMNKVYDLKGSSQGRTN--KK--IKVRDKTILKDIDLD-----FCFYVDSLAR 197  thale cress
AAD10191     1881 n--------tekKLDLLVMENLFY-GRKMAQVFDLKGSLRNRNVktDT--GKESCDVVLLDENLLkmvrdNPLYIRSHSK 1949 house mouse
NP_510155    1330 ----------tlKVDILVMEYLFY-NHNVSQVWDLKGSLRNRLA--ST--GKSANEMVLLDENFVkdlwnQQLYVLPHSK 1394 nematode
NP_001190899 1562 ----------efKMDVLVMENLLF-KRNFTRLYDLKGSTRARYN--PD---TSGSNTVLLDQNLVeamptSPIFVGSKAK 1625 thale cress
NP_596090    1763 g--------ticKTDIMIMENVFY-DECPSRIFDLKGSMRNRHV--E---STGKVDEVLLDENLVeliyeSPIFVSEQLK 1828 Schizosacchar...
2GK9_A        231 KIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCS--------Ltgppalvgs------- 295  human
O04095        656 EALFKQIYLDCSFLESLNIIDYSLLLGLHFRAPGQLNDILEPPNAMSDQESVSSV--------Dvgltqehsippkglll 727  thale cress
O48709        548 QAFINQIDLDCEFLEAERIMDYSLLIGLHFRESGMRDDISLGIGRRDQEDKLMR-------------------------- 601  thale cress
O04613        220 QRIIKQTKLDCELLEEEGIMDYSLLVGLQSKGSCQGSLDGLNPVYGSFAPPSSFK--------Snstksmktassspdrs 291  thale cress
XP_002879915  605 QEFIRQIDKDCEFLEQERIMDYSLLVGIHFREASVAGELIPSGARTPIGESEEESgprlsraeV---------------- 668  Arabidopsis l...
O23705        198 HRLIKQTKLDCELLEDEGIMDYSLMLGLQVKGSCHGSIDELIPVYDSFTSRGSVD--------Snsskfmktasnspdrs 269  thale cress
AAD10191     1950 SELRTSIHSDAHFLSSHLIIDYSLLVGRDDTSN----------------------------------------------- 1982 house mouse
NP_510155    1395 AAMNQAISNDSHFLSSQYIMDYSLLVGVDDDNG----------------------------------------------- 1427 nematode
NP_001190899 1626 RLLERAVWNDTSFLASIHVMDYSLLVGVDEERN----------------------------------------------- 1658 thale cress
NP_596090    1829 SLLHSCLWNDTLFLSKLNIMDYSLIVGIDYTKK----------------------------------------------- 1861 Schizosacchar...
2GK9_A        296 -----------------------------------ygtspegiGGYIHSHRPLGPGEFESfIDVYAIRSAEgap------ 334  human
O04095        728 vth---------------------epnsvntapgphirgstlrAFSVGEQEVDLILPGTArLRVQLGVNMPaqahhklie 786  thale cress
O48709        602 --------------------------------------------------GNGPLMRLGEsTPAKAEQVSRfeeetweed 631  thale cress
O04613        292 svamyscspdrd---svenemsmtiqsvtsnsassetnilattLSDLFHNSSNIN-------FGMKIPARArrvtret-- 359  thale cress
XP_002879915  669 -------------------------------------------DELLSDPSRWASIRLGTnMPARAERTMRkndcelqlv 705  Arabidopsis l...
O23705        270 sstmysctpsrnsvdsensvniqsvasispspaqtnasdspyeSLVSKTNLTNIFQNSSStNFGMKIPGRArrvgrgesg 349  thale cress
AAD10191          --------------------------------------------------------------------------------      house mouse
NP_510155         --------------------------------------------------------------------------------      nematode
NP_001190899      --------------------------------------------------------------------------------      thale cress
NP_596090         --------------------------------------------------------------------------------      Schizosacchar...
2GK9_A        335 --------------qkEVYFMGLIDILTQYDAKKKAAHAAKTVKHGa--G----AEISTVHPEQYAKRFLDFITNIF 391  human
O04095        787 dke-esatielfevydVVVYMGIIDILQEYNTKKKVEHTCKSLQYD---P----MTISVTEPSTYSKRFVNFLHKVF 855  thale cress
O48709        632 aidnsnpkgtrkeaveVILYFGVIDILQDYDITKKLEHAYKSLHAD---P----ASISAVDPKLYSRRFRDFINKIF 701  thale cress
O04613        360 ---------geeewynVVLYIGIVDTFQDYGMKKRIEHCYKSIQYN---S----NSISTVHPKIYSSRFQDFVSNIF 420  thale cress
XP_002879915  706 -------geptgefyeVVMIFGIIDILQDYDISKKLEHAYKSIQYD---P----SSISAVDPRQYSRRFRDFIFKVF 768  Arabidopsis lyra...
O23705        350 svvgkqsreggeewydVILYLGIIDIFQDYGVRKRLEHCYKSIQHS---S----KTISAVHPKMYSSRFQDFVSQIF 419  thale cress
AAD10191     1983 -----------------ELVVGIIDYIRTFTWDKKLEMVVKSTGILggqG----KMPTVVSPELYRTRFCEAMDKYF 2038 house mouse
NP_510155    1428 -----------------ELILGIVDYMRTYTLDKKLESWVKIVAIP---Ga---HLPTILSPEMYCARFSEAIDSYF 1481 nematode
NP_001190899 1659 -----------------ELVLGIIDFMRQYTWDKHLETWVKTSGLL---GgpknSTPTVISPQQYKKRFRKAMTAYF 1715 thale cress
NP_596090    1862 -----------------ELYVGIIDFIRTYTWDKKLESWVKEKGLVg-rG----PEPTIVTPKQYKNRFRKAMDCYI 1916 Schizosaccharomy...
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