1EWF


Conserved Protein Domain Family
BPI2

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smart00329: BPI2 
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BPI/LBP/CETP C-terminal domain
Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain
Statistics
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PSSM-Id: 128624
View PSSM: smart00329
Aligned: 17 rows
Threshold Bit Score: 167.103
Threshold Setting Gi: 82122712
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1EWF_A    250 HDRMVYLGLSDYFFNTAGLVYQEAGVLKMTL-RDDMIPKESK-FRLTTK---------FFGTFLPEVAKKFPNM-KIQIH 317 human
Q05704    417 DNTNSQLAISANFLSSVLTMLQKQGALDIDI-TDGMFEDLP---PLTTS---------TLGALIPKVFQQYPESrPLTIR 483 Norway rat
Q05701    273 HTSQVTVPL--YLFNTVFGLLQTNGALDLDI-TPEMVPRN---IPLTTT---------DLAALAPEALGKLPPGqHLLLS 337 Norway rat
Q18869    337 KDSMIELVVSDFLPNSLLYHAYVQRFIKVLL-TPRTKGVSS--FLRTTCeg-----sfCISDLAPQLAEQYPNS-TVELA 407 Caenorhabditis ele...
O42273    238 STSHLILALSEHFYTSLYFTLERAGAFNMTI-PS---------MLTTAT---------LAQKIT-QVGSLYHEDlPITLS 297 chicken
Q17743    284 SGHMIDFYLSNYTMSSLLFWMDQYRKFDYEIsRQATNNSALVgYLKTDCgtg----diCAGTLFPALGTRFPGG-EVVIK 358 Caenorhabditis ele...
Q17738    331 PSQMLQIVVSDFVPNSLMFHGHRI-KLFDTR-IDWMTPQFGP-VMRTTCdlst-gslfCIGDLFPALREMLPDR-NVAFL 405 Caenorhabditis ele...
Q23366     51 SDHMAHFYVSDHLLNSMLYQAYQDNRLALKI-DESNLPNEMKsFVSTQCptkkhqtyvCVGYLIPEIRHLYPDS-TVSFA 128 Caenorhabditis ele...
EAW75784  280 EERMVYVAFSEFFFDSAMESYFRAGALQLLL-VGDKVPHDLD-MLLRAT---------YFGSIV-LLSPAVIDS-PLKLE 346 human
NP_509863 267 STRMIDMFIDEHTVQSIIAAAHFAGHLKTKI--------ESP-FLKTSCdv------lCIGTVLPELAEQVPNR-TLSVE 330 nematode
1EWF_A    318 VSASTPPHLSVQPTGLTFYP---AVDVQAFAVLPNS----ALASLFLIGMHTTGSM-EVSAESNRLVGELKLDRLLLELK 389 human
Q05704    484 IQVPNPPTVTLQKDKALVKV---FATSEVVVSQPND----VETTICLIDVDTDLLA-SFSVEGDKLMIDAKLDKTSLNLR 555 Norway rat
Q05701    338 LRVMKSPMILLQNKKVTVSI---PVTIHVLSSVPQG----TPVALFQMNGVMTLNA-HLVPSTTKLHISLSLERLTVQLA 409 Norway rat
Q18869    408 MSATRAPAVLFSEKNGGTISvslGGLVVVFAVNGNQ-----RRQVIVVDLDVVADA-RLSIQGHNVSGSVELRKFDLKRR 481 Caenorhabditis ele...
O42273    298 AALRSSPRVVLEEGRAALKL---FLTVHIGAGSPDFq---SFLSVSADVTRAGLQL--SVSDTRMMISTAVIEDAELSLA 369 chicken
Q17743    359 SHTVSYPRVVLRKNNMTIYI---DSRVDAFVQQQDR----SRRFL-TASMNAEVKLdKPSFKDFVLHGELRIDKFKVSDV 430 Caenorhabditis ele...
Q17738    406 FTTLRAPAVIMQPEEKGGI----HFSLRGLIRLVSD----RNEPIGEMEIRIEALM-KMKLTSKSVKGKVTIEEIQFTS- 475 Caenorhabditis ele...
Q23366    129 ILPHGLPYVMFNRDGMTVDI---KNRILTYAIPDDPahlnNRSQILVFSINGQADI-TFAPTTESLNAHMNLNRFNVRLH 204 Caenorhabditis ele...
EAW75784  347 LRVLAPPRCTIKPSGTTISV---TASVTIALVPPDQ----PEVQLSSMTMDARLSA-KMALRGKALRTQLDLRRFRIYSN 418 human
NP_509863 331 AATLSPPVIDLQQGRALVYL---NASLNVFAAPPLKt---VEGSMLTINVETEFTL-TMEMRNKRVKGYINMINAQANLV 403 nematode
1EWF_A    390 HSNIG-----------PFPVELLQDIMn-YIVPILVLPRVNEKLQKGFPLPTPARVQLYNVVLQPHQNFLLFGA 451 human
Q05704    556 TSNVG-----------NFDVFILEMLVe-KIFDLAFMPAMNAILGSGVPLPKILNIDFSNADIDVLEDLLVLST 617 Norway rat
Q05701    410 SSFSQ-----------PFDASRLEEWLs-DVVRAAYMQKLNEHLEVGIPLPKILNVNFANSVVDVIENAVVLTV 471 Norway rat
Q18869    482 TGTVD-----------ISDAEIDDIALlvSQLSENLL---NGLLVNGMPIPLPHVLRIKDSHINVLSRRMHIQV 541 Caenorhabditis elegans
O42273    370 ASNVG-----------LVRAALLEELFl-APVCQQVPAWMDDVLREGVHLPHMSHFTYTDVNVVVHKDYVLVPC 431 chicken
Q17743    431 ASLVD-----------GIDEGSLEFLVn-ALTELILNEDMAKKLKSGIQLPIMFDYTQQAANVSIEDDMLHISA 492 Caenorhabditis elegans
Q17738    476 -RSPR-----------ILLQEELDDAG--FLSREILQRMVNDILRQGIPIPIHPLFKLVKPKLTLLSRSMLLET 535 Caenorhabditis elegans
Q23366    205 RSAVR-----------GIDESSIARLS--PLSKTFIAPRLSSAVEKAVRFPMQDTIKFINPVIKNYDGFICLST 265 Caenorhabditis elegans
EAW75784  419 HSALE-----------SLALIPLQAPLk-TMLQIGVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGA 480 human
NP_509863 404 DSKVGlmsqktvdflvNMSTPFLEDAVd-VLIGRGLI------VADPFQFPSTNEHLSIHDKCLRWEADIVMPT 470 nematode
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