1BP1_A 8 RISQKGLDYASQQGTAA---LQKELKRIKIPDYSDSFKIKHl--------------GKGHYSFYSMDIREFQLPS---SQ 67 human Q18869 50 RILPRGLAYLNHLAANL---LADQLPRLILPDVEHILPSNQ---------------GIIYISKVHLSRFRRAEHH---QL 108 Caenorhabditis ... O17781 66 RLNSRAFQYASTLVGGI---LNTEIKKARIPPISQCIPMVQ-----------------GCVNIYNLYVSRYRCPQr-vVL 124 Caenorhabditis ... O17768 42 riMPNGLAYLREVGMKV---INEQILKLQLPNIREPIEN-------------------GEVSIYNLQMSKYWAPQe-yAL 98 Caenorhabditis ... Q17151 1 ---QEALDYGSRIAPDV---LRKVLNKASFENLEDKE-------------------GPVSYKFSKISLEQSEIES---AN 52 Biomphalaria gl... Q17738 19 RVTPTGTQYVASVVAAA---FSSHFADIKPPKERKDHQLTT----------------ISTVTLRRLMLETLQLDKq-lVT 78 Caenorhabditis ... Q05701 30 RIDKDELGKAIQNSLVGgpiLQNVLGTVTSVNQGLLGAGGLlgggg------llsyGGLFSLVEELSGLKIEELT---LP 100 Norway rat Q05704 171 GGLLGTGGILANEGILA---GQGGLLGGGGLLGDGG----LlggggvlgvlgeggiLSTVQGITGLRIVELTLPR---VS 240 Norway rat XP_002826500 31 RITKPALLVLNQETAKV---IQTAFQRASYPDITGEKAMMLl--------------GQVKYGLHNIQISHLSIAS---SQ 90 Sumatran orangutan NP_509863 21 RVNEFGLHEAANFTRQW---LSMAGPHMKMPEIR------Qs--------------FYNSFAGGEMTVTNITIKRfvpPL 77 nematode
1BP1_A 68 ISMVPNVg-LKFSISNANIKISGKWKAQKRF-------LKMSGNFDLSIEGMSISADLKLGSNPtsg--kpTITCSSCSS 137 human Q18869 109 NSTAPNK--ISWTMQNMDIGLLGDLSGSVNIvv----pLNLTGQVEILAQGLTFHLESSIEKGKng---saKVTSLSCLA 179 Caenorhabditis ... O17781 125 YPAPPNR--IVLQVQNVDLGVTGNLGGQIVVll----pIALSGIVQLNIHQATITVQLAIERGPrg----pYVRLLSCDM 194 Caenorhabditis ... O17768 99 DMSEPST--FAWSMSKMHLRAAGDFQATLNSpll-lptVPITGHFEALLGHISLYITVNMERNAng---apQVRSTGCRS 172 Caenorhabditis ... Q17151 53 FSFDPSIngIRASIQRLSAFVRLDYESSIDM-------SITKMEHSGSVDIPSGCRCGPESCRErds-vrrAKPNLECKA 124 Biomphalaria gl... Q17738 79 TTTSDGL--LRITVQNISVSSSAVLSGELRE-------IKLQDNVTFRTANLRIDTAIRIMKNAgg---npALKMESCKI 146 Caenorhabditis ... Q05701 101 TVSIKL---LPGVGVQLSLHTKVSLHGSGP----------LVGLLQLAAEVNVSSKVALGMSPRgt----pILILKRCNT 163 Norway rat Q05704 241 VRLLPG---VGVYLS-LYTRVAINGKSLIGF-------------LDIAVEVN-ITAKVRLTMDRtg---ypRLVIERCDT 299 Norway rat XP_002826500 91 VELVEAKs-IDVSIQNVSVVFKGTLKYGYTT-------AWWLGIDQSIDFEIDSAIDLQINTQLtcdsgrvRTDAPDCYL 162 Sumatran orangutan NP_509863 78 IRFRPSDh-SFLYMSTLSGYAQVSAEWAVESqflhmlkIPLEGQIHAQMTGLISEIAMQITQDN-------EVEVHHCVA 149 nematode
1BP1_A 138 HINSVHVHIS--Ks-KVGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSKLQPY---FQTLPVMTKId--------sVA 203 human Q18869 180 TIRDVTVTNHngG--LFGLAVSVFKQGVSDNVRHMLQTIICKKVRKYIDEDANEK---LAEAQTSSKLad-------aLE 247 Caenorhabditis ... O17781 195 QIGYADAYIEngGl-VGDIVNSQFRSQISNQVRQMIPGQVCGQLPTIINEKINSK---LGALPQTVALqq-------mIS 263 Caenorhabditis ... O17768 173 AIGYVDLNVRntGv-ITDFFINAFKAFLIGNFKPQVEQKMCKMIESIIDRDMNIL---LSNMPLKIRInen-----nlDI 243 Caenorhabditis ... Q17151 125 SIKDSEFNFS--Si-VVHWMYSTMSKVLPNKVREWTEERLCRVITDYIDNKMPET---IKEVKLSAEMd---------EF 189 Biomphalaria gl... Q17738 147 VTQGIKLVT---Kp-MDPRNGKSLADAIANDANTMFSDLICSKIDHIVSNRVNQR---FALLSSRISLe--------dSK 211 Caenorhabditis ... Q05701 164 LLGHISLTS--------GLLPTPIFGLVEQTLCKVLPGLLCPVVDSVLSVVNELLgatLSLVPLGPLGsveftlatlpLI 235 Norway rat Q05704 300 LLGGIKVKL------LRGLLPNLVDNLVNRVLANVLPDLLCPIVD-VVLGLVNDQ---LGLVDSLVPLg--------iLG 361 Norway rat XP_002826500 163 SFHKLLLHLQ--GerEPGWIKQLFTNFISFTLKLVLKGQICKEI-NVISNIMADF---VQTRAASILSd--------gDI 228 Sumatran orangutan NP_509863 150 QIRDLRVAFE--Gs-VAADVIHWFRQSITRAIRRTLEEEYCDMMRNHWLPWVEAQ---LYQFPTNLTIs----------H 213 nematode
1BP1_A 204 GINYGLVAPPAT---T-------AETLDVQMKGEFYSENH 233 human Q18869 248 TNALKMISVGGD---Eksr-idiSSIFDSSLASKFFIDFR 283 Caenorhabditis elegans O17781 264 LFGGALGLGGGG---G-------GTCPSTCPKQPVFIPST 293 Caenorhabditis elegans O17768 244 IGETFGVAPRKH---H-------RAGKLSNLNAKNITLTH 273 Caenorhabditis elegans Q17151 190 KVDYSPVSKVSV---S-------QQSLKPDTGVKFQWKSD 219 Biomphalaria glabrata Q17738 212 NFDIVKIIMQAE------------ERLKRLVRQNMLRSNK 239 Caenorhabditis elegans Q05701 236 SNQYIELDINPI---VksiagdvIDFPKPRLPVKMPPKED 272 Norway rat Q05704 362 SVQYTFSSLPLV---T-------GEFLELDLNTLVGEAGG 391 Norway rat XP_002826500 229 GVDISLTGDPVI---T-------ASYLESHHKGHFIYKNv 258 Sumatran orangutan NP_509863 214 NPDVTLIQTMQSiamT-------QHHVDVRMRSDLIWDDE 246 nematode
Jiyao W et al.(2023). "The conserved domain database in 2023.",