2E5R,1TOT


Conserved Protein Domain Family
ZnF_ZZ
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smart00291: ZnF_ZZ 
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Zinc-binding domain, present in Dystrophin, CREB-binding protein.
Putative zinc-binding domain present in dystrophin-like proteins, and CREB-binding protein/p300 homologues. The ZZ in dystrophin appears to bind calmodulin. A missense mutation of one of the conserved cysteines in dystrophin results in a patient with Duchenne muscular dystrophy.
Links
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Statistics
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PSSM-Id: 197633
Aligned: 25 rows
Threshold Bit Score: 48.9744
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2E5R_A       8 VFHPVECSYCHS-EsMMGFRY-RCQQCHNYQLCQDCFWRG-HAGGSHS 52   human
XP_547610  237 VFHPVECSYCHS-EsMMGFRY-RCQQCHNYQLCQDCFWRG-HAGGSHS 281  dog
CAD67583  3180 aKHQAKCNICKEcP-IVGFRY-RSLKHFNYDVCQSCFFSG-RTAKGHK 3224 torafugu
EGA83037   254 IHKVYICHTCGN-E-SINVRY-HNLRARDTNLCSRCFQEG-HFGANFQ 297  Saccharomyces cerevisiae Lalvin QA23
EGA87282     1 MSNKFHCDVCSAdC-TNRVRV-SCAICPEYDLCVPCFSQG-SYTGKHR 45   Saccharomyces cerevisiae VL3
NP_510230   19 DCQFEDCADCGL-V-ILGSMF-TCNLCENHHICASCYNDTvVEESIHS 63   nematode
NP_595386   56 RSSSVACNTCLK-I-IRNDSF-HCTKCFDFDVCRDCYAK---QAFLHP 97   Schizosaccharomyces pombe 972h-
CAB10418    27 GGGKYNCDYCQKdI-TGKIRI-KCAVCPDFDLCIECMSV--GAEITPH 70   thale cress
NP_510230   93 PVHDNPCASCGSkV-FPGLRYvCPEICPDYGICATCFIK--KKGTEEI 137  nematode
CAM27315   628 VKHQTKCSICRQcP-IKGFRY-RSLKQFNVDICQTCFLTG-RASKGNK 672  house mouse
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