1WIM,1FBV,2CKL


Conserved Protein Domain Family
RING

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smart00184: RING 
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Ring finger
E3 ubiquitin-protein ligase activity is intrinsic to the RING domain of c-Cbl and is likely to be a general function of this domain; Various RING fingers exhibit binding activity towards E2 ubiquitin-conjugating enzymes (Ubc' s)
Statistics
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PSSM-Id: 214546
Aligned: 276 rows
Threshold Bit Score: 28.2438
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1WIM_A      8 CKLCLGEYp-------------vEQMTTIAQ-CQCi-FCTLCLKQYVEllikegleTAISCPDA 56  human
O44238    130 CQPCIRRP---------------CPPCIRKP-CIRr-PCQPCIRR--------------PCPPC 162 Ciona intestinalis
O48794    209 CHQCLKGEr--------------ITLLICSE-CEKtmFCLQCIRKWYPnls--eddVVEKCPLC 255 thale cress
NP_054172 212 CNVCKEIStd------------erFLKPKEC-CEYa-ICNACCVNMWKta-----ttHAKCPAC 256 AcMNPV
EDN63042   33 CPLCIEPMdi------------tDKNFFPCP-CGYq-ICQFCYNNIRQnp-----elNGRCPAC 77  Saccharomyces cerevisiae YJM789
NP_564218 155 CGICLEP-----------------CTKMVLPnCCHa-MCIKCYRNWNTks--------eSCPFC 192 thale cress
NP_046308  39 CAVCLETYcvqs--------nniIDFLMPSE-CTHl-FCYKCVLNMYKnamn-vpraAVSCPMC 91  OpMNPV
AAA46733   86 CSVCLETYsqqs--------ndtCPFLIPTT-CDHg-FCFKCVINLQSnamn-iphsTVCCPLC 138 AcMNPV
NP_054118   8 CNICFSVAeiknyflqpidrltiIPVLELDT-CKHq-LCSMCIRKIRKr-------kKVPCPLC 62  AcMNPV
XP_864751 405 CIICSEY----------------FIEAVTLN-CAHs-FCSYCINEWMK--------RKVECPIC 442 dog
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