1HIB,2MIB,2KKI,2IRT


Conserved Protein Domain Family
IL1

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smart00125: IL1 
Click on image for an interactive view with Cn3D
Interleukin-1 homologues
Cytokines with various biological functions. Interluekin 1 alpha and beta are also known as hematopoietin and catabolin.
Statistics
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PSSM-Id: 128430
View PSSM: smart00125
Aligned: 39 rows
Threshold Bit Score: 174.105
Threshold Setting Gi: 1170529
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HIB_A         3 VRSLNCGLRDS-QQKSLVMSGPYELKALHLQgqDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKdDKPTLQ 81  human
P79161       129 VIHQECILNDAlNQSIIRDMSGPYLMAATLN--NLEEAVKFDMVAYVSEE-DSQLPVTLRISKTQLFVSAQNE-DEPVLL 204 goat
AAR97734     129 VIHQECILNDAlNQSIIRDMSGPYLTAATLN--NLEEAVKFDMVAYVSEE-DSQLPVTLRISKTQLFVSAQNE-DEPVLL 204 water buffalo
Q28385       129 IVNHQCTLNDAlNQSVIRDTSGQYLATAALN--NLDDAVKFDMGAYTSEE-DSQLPVTLRISKTRLFVSAQNE-DEPVLL 204 horse
NP_776517    129 VIHQECILNDAlNQSIIRDMSGPYLTATTLN--NLEEAVKFDMVAYVSEE-DSQLPVTLRISKTQLFVSAQNE-DEPVLL 204 cattle
NP_999194    129 VINHQCILNDArNQSIIRDPSGQYLMAAVLN--NLDEAVKFDMAAYTS-NDDSQLPVTLRISETRLFVSAQNE-DEPVLL 204 pig
NP_001009808 129 VIHQECILNDAlNQSIIRDMSGPYMTAATLN--NLEEAVKFDMVAYVSEE-DSQLPVTLRISKTQLFVSAQNE-DEPVLH 204 sheep
AAA73198     129 VINHQCILNDArNQSIIRDPSGQYLMAAVLN--NLDEAVKFDMAAYTS-NDDSQLPVTLRISETRLFVSAQNE-DEPVLL 204 pig
NP_058715    131 IVKQEFIMNDSlNQNIYVDMDRIHLKAASLN--DLQLEVKFDMYAYSSGGDDSKYPVTLKVSNTQLFVSAQGE-DKPVLL 207 Norway rat
NP_001095154 129 IIKQEFTLNDAlNQSLVRDTSDQYLRAAPLQ--NLGDAVKFDMGVYMTSE-DSILPVTLRISQTPLFVSAQNE-DEPVLL 204 rabbit
1HIB_A        82 LESVDPKNYPK-KKMEKRFVFNKIeINNKLEFESAQFPNWYISTSQAENmpVFLGGTKGGqdITDFTMQ 149 human
P79161       205 KEMPETPKIIK-DETNLLFFWEKH--GSMDYFKSVAHPKLFIATKQEKL--VHMASGPPS--ITDFQIL 266 goat
AAR97734     205 KEMPETPKIIK-DETNLLFFWEKH--GSMDYFKSVAHPKLFIATKQEKL--VHMASGPPS--VTDFQIL 266 water buffalo
Q28385       205 KEMPDTPKTIK-DETNLLFFWERH--GSKNYFKSVAHPKLFIATKQGKL--VHMARGQPS--ITDFQIL 266 horse
NP_776517    205 KEMPETPKIIK-DETNLLFFWEKH--GSMDYFKSVAHPKLFIATKQEKL--VHMASGPPS--ITDFQIL 266 cattle
NP_999194    205 KELPETPKTIK-DETSLLFFWEKH--GNMDYFKSAAHPKLFIATRQEKL--VHMAPGLPS--VTDFQIL 266 pig
NP_001009808 205 KEMPETPKIIK-DETNLLFFWEKH--GSMDYFKSVAHPKLFIATKQEKL--VHMASGPPS--ITDFLIL 266 sheep
AAA73198     205 KELPETPKTIK-DETSLLFFWEKH--GNMDYFKSAAHPKLLIATRQEKL--VHMARGLPS--VTDFQIL 266 pig
NP_058715    208 KEIPETPKLITgSETDLIFFWEK--INSKNYFTSAAFPELLIATKEQSQ--VHLARGLPS--MIDFQIS 270 Norway rat
NP_001095154 205 KEMPETPRIITdSESDILFFWETQ--GNKNYFKSAANPQLFIATKPEHL--VHMARGLPS--MTDFQIS 267 rabbit
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