1LI1


Conserved Protein Domain Family
C4

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smart00111: C4 
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C-terminal tandem repeated domain in type 4 procollagens
Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.
Statistics
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PSSM-Id: 128421
View PSSM: smart00111
Aligned: 16 rows
Threshold Bit Score: 175.271
Threshold Setting Gi: 2190498
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1LI1_A        115 AMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTsA-GAEGSGQALASPGSCLEEFRSAPFIECHG-RGTCNYYA-NAYSF 191  human
Q26640       1526 GHFITRHSQSRNVPSCPAGTVELWRGFSVLFSM-G-NGHAHHQDLGDAGSCLQRFSTMPFLFCNF-NNVCNYASrNDRSY 1602 Strongylocent...
O18407       1513 GFIFARHSQSVHVPQCPANTNLLWEGYSLSGNV-A-ASRAVGQDLGQSGSCMMRFTTMPYMLCDI-TNVCHFAQnNDDSL 1589 fruit fly
P27393       1533 GFLLVKHSQTSEVPQCPPGMVKLWDGYSLLYIE-G-NEKSHNQDLGHAGSCLSRFSTMPFLFCDV-NNVCNYASrNDKSY 1609 pig roundworm
AAA28404     1659 ANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHT-AvGNGGGGQALQSPGSCLEDFRATPFIECNGaKGTCHFYE-TMTSF 1736 fruit fly
AAA28404     1554 GILITRHSQSETVPACSAGHTELWTGYSLLYVD-G-NDYAHNQDL---GSCVPRFSTLPVLSCGQ-NNVCNYASrNDKTF 1627 fruit fly
NP_001022662 1535 GFTFAKHSQTTAVPQCPPGASQLWEGYSLLYVQ-G-NGRASGQDLGQPGSCLSKFNTMPFMFCNM-NSVCHVSSrNDYSF 1611 nematode
CAA40299     1644 TQIIAVHSQDTSVPQCPQGWSGMWTGYSFVMHT-AaGAEGTGQSLQSPGSCLEEFRAVPFIECHG-RGTCNYYAtN-HGF 1720 nematode
NP_001160001 1445 GFVFTRHSQTTAIPSCPEGTEPLYSGFSLLFVQ-G-NEQAHGQDLGTLGSCLQRFTTMPFLFCNI-NDVCNFASrNDYSY 1521 cattle
Q17163       1677 ANVIAVHSQTIQIPNCPNGWNSLWIGYSFAMHT-GaGREGGGQSLSSPGSCLEDFRATPFIECNGaRGSCHYFAnKFSFF 1755 Brugia malayi
1LI1_A        192 WLATIERSEMFKKPTPSTLKA-G-ELRTHVSRCQVCMRR 228  human
Q26640       1603 WLTTN-------EPLPMMPLM-NqQIDPYISRCTVCEAP 1633 Strongylocentrotus purpuratus
O18407       1590 WLSTAEP-----MPMTMTPIQ-GrDLMKYISRCVVCETT 1622 fruit fly
P27393       1610 WLST-------TAPIPMMPVSeG-GIEPYISRCAVCEAP 1640 pig roundworm
AAA28404     1737 WMYNLESSQPFERPQQQTIKA-G-ERQSHVSRCQVCMKN 1773 fruit fly
AAA28404     1628 WLTTN-------AAIPMMPVE-NiEIRQYISRCVVCEAP 1658 fruit fly
NP_001022662 1612 WLSTDEP-----MTPMMNPVT-GtAIRPYISRCAVCEVP 1644 nematode
CAA40299     1721 WPSIVDQDKQFRKPMSQTLKA-G-GLKDRVSRCQVCLKN 1757 nematode
NP_001160001 1522 WLSTPAM-----IPMDMAPIT-GrALEPYISRCTVCEGP 1554 cattle
Q17163       1756 WLTTIEDDQQFRIPESETLKS-G-SLRTRVSRCQVCIKA 1792 Brugia malayi
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