Conserved Protein Domain Family
WNT1

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smart00097: WNT1 
found in Wnt-1
Statistics
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PSSM-Id: 128408
View PSSM: smart00097
Aligned: 19 rows
Threshold Bit Score: 378.971
Threshold Setting Gi: 74967393
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q27886        55 SDLLHSRalrSIQLACRTHPATVISAFEGVQEGLQNCANRLRFQQWDCSEA-G---N-IMH---DPPLLRQGFRESSLIW 126 Caenorhabditis ...
XP_220546    116 SIPGLVP---KQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTV-S---NsLAI---FGPVLDKATRESAFVH 185 Norway rat
NP_001079343  44 TIPGLVA---KQMRFCRNYMEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVnD---N-LAI---FGPVLDKATRESAFVH 113 African clawed ...
P21551        59 SLQLLSR---KQRKLIRQNPGILHSINSGLQSAMKECKWQFRSRRWNCPTT-G---G-DNI---FGKIVNKGCRETAFIF 127 axolotl
XP_003252539 101 SLQLLSR---KQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTA-P---G-PHL---FGKIVNRGCRETAFIF 169 White-cheeked G...
P21552        43 NVPGLVS---RQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTL-Dr--D-HSL---FGRVLLRSSRESAFVY 112 house mouse
NP_001037315  57 vHATLRR---KQRRLARENPGVLAAVAK-AQYAFAECQHQFKYRRWNCSTR-NflrG-KNL---FGKIVDRGCRETAFIY 127 domestic silkworm
NP_001081637  22 SAWSVNN---FLMTGPKAYLTYSASVAVGAQNGIEECKYQFAWERWNCPES-T---L-QLA---THNGLRSATRETSFVH 90  African clawed ...
NP_493668     44 SLKGLTR---RQMRFCKKNIDLMESVRSGSLAAHAECQFQFHKRRWNCTLI-D---P-VTHeviPDVFLYENTRESAFVH 115 nematode
NP_571034     22 CGWSVNN---FLMTGPKAYLIYSSSVAAGAQSGIEECKYQFAWDRWKCPER-A---L-QLS---THSGLRSANRETAFFH 90  zebrafish
Q27886       127 ALSSASAAWGVATACAQGWIDDCACNNQMG---------Q------NEYEFGGCTHGVQHGITASRKLLTKVGA-V---- 186 Caenorhabditis ...
XP_220546    186 AIASAGVAFAVTRSCAEGSAAICGCSSRLQ---------Gsp---gEGWKWGGCSEDIEFGGMVSREFADAREN-R---- 248 Norway rat
NP_001079343 114 AIASAGVAFAVTRSCAEGSATICGCDTHHK---------Gpp---gEGWKWGGCSEDMDFGSMVSREFADAREN-R---- 176 African clawed ...
P21551       128 AITSAGVTHSVARSCSEGSIESCTCDYRRR---------Gpg---gTDWHWGGCSDNIDFGRVFGREFVDSSER-G---- 190 axolotl
XP_003252539 170 AITSAGVTHSVARSCSEGSIESCTCDYRRR---------Gpg---gPDWHWGGCSDNIDFGRLFGREFVDSGEK-G---- 232 White-cheeked G...
P21552       113 AISSAGVVFAITRACSQGELKSCSCDPKKK---------GsakdskGTFDWGGCSDNIDYGIKFARAFVDAKERkG---- 179 house mouse
NP_001037315 128 AITSAGVTHSLARACREASIESCTCDYSHRpraaqnpvgGra--nvRVWKWGGCSDNIGFGFRFSREFVDTGER-G---- 200 domestic silkworm
NP_001081637  91 AISSAGVMYTLTRNCSMGDFDNCGCDDSRN---------Gri--ggRGWVWGGCSDNAEFGERISKLFVDGLET-G---- 154 African clawed ...
NP_493668    116 AISSAAVAYKVTRDCARGISERCGCDYSKN---------Dhs--gkSQFQYQGCSDNVKFGIGVSKEFVDSAQR-Rvlmm 183 nematode
NP_571034     91 AISSAGVMYTLTRNCSLGDFDNCGCDDTRN---------Gqr--ggQGWLWGGCSDNVGFGEVISKQFVDALET-G---- 154 zebrafish
Q27886       187 ---------------NTLLRKVEKHNLKAGRLAIKKTLISSCKCHGVSGSCQQKTCWKRTATLEHITDYLVEKYARAKLY 251 Caenorhabditis ...
XP_220546    249 ---------------PDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEM 313 Norway rat
NP_001079343 177 ---------------PDARSAMNRHNNEAGRTSILDHRHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEM 241 African clawed ...
P21551       191 ---------------RDLRYLMNRHNNEAGRMTVFSEMKQECKCHGMSGSCAVRTCWMRLPTFRAVGDFLKDRFDGASRV 255 axolotl
XP_003252539 233 ---------------RDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRV 297 White-cheeked G...
P21552       180 ---------------KDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGEYLWRKYNGAIQV 244 house mouse
NP_001037315 201 ---------------KTLREKMNLHNNEAGRRHVQTEMKQECKCHGMSGSCTVKTCWMRLPSFRSVGDSLKDRFDGASRV 265 domestic silkworm
NP_001081637 155 ---------------QDARALMNLHNNEAGRLAVKETMKRTCKCHGISGSCSIQTCWLQLAEFRDIGNHLKIKHDQALKL 219 African clawed ...
NP_493668    184 kddngtsllgpsqlsADGMHMINLHNNQAGRQVLEKSLRRECKCHGMSGSCEMRTCWDSLPNFRHIGMAIKDKFDGAAEV 263 nematode
NP_571034    155 ---------------QDARAAMNLHNNEVGRKAVKGTMQRTCKCHGVSGSCTTQTCWLQLPEFREVGNYLKEKYHRAVKV 219 zebrafish
Q27886       252 TDDSV-----------------------------------VKTTDLIYLEASPDVCKAKSVA------GRVCAWRNETHT 290 Caenorhabditis ...
XP_220546    314 VVEKHresrgwvetl----------------rprytyfkvPTERDLVYYEASPNFCEPNPETgsfgtrDRTCNVSSHGID 377 Norway rat
NP_001079343 242 VVEKHresrgwvetl----------------rpkytffkpPIERDLIYYESSPNFCEPNPETgsfgtrDRECNVTSHGID 305 African clawed ...
P21551       256 IYGNKgsnrasrvqth-------------hlepenpthkpPSPQDLVYFEKSPNFCTYNGKTgtsgtsGRVCNSSSLGLD 322 axolotl
XP_003252539 298 LYGNRgsnrasraell-------------rlepedpahkpPSPHDLVYFEKSPNFCTYSGRLgtagtaGRACNSSSPALD 364 White-cheeked G...
P21552       245 VMNQDgtgftva----------------------nkrfkkPTKNDLVYFENSPDYCIRDREAgslgtaGRVCNLTSRGMD 302 house mouse
NP_001037315 266 MLSKAdvetpaqrneaaphrvprkdryrfqlrphnpdhksPGVKDLVYLESSPGFCEKNPRLgipgthGRACNDTSIGVD 345 domestic silkworm
NP_001081637 220 EMDKRkmrsgnsadn---------------rgaiadafssVAGSELIFLEDSPDYCLKNISLglqgteGRECLQSGKNLS 284 African clawed ...
NP_493668    264 KVVKEdgiekpriv------------------mknsqfkrHTNADLVYMTPSPDFCESDPLRgilgtkGRQCTLAPNAID 325 nematode
NP_571034    220 DLLRGagnsaasrg------------------aiaetfnsISRKELVHLEDSPDYCLENRTLglpgteGRECLRKGKNLS 281 zebrafish
Q27886       291 q---gDCDRLCCGNGFSI--R--HEVVRVKCDCEFVWCCNLVCKDCIQHRWISTCN 339 Caenorhabditis elegans
XP_220546    378 -----GCDLLCCGRGHNA--R--TERRREKCHCVFHWCCYVSCQECTRVYDVHTCK 424 Norway rat
NP_001079343 306 -----GCDLLCCGRGQNT--R--TEKRKEKCHCIFHWCCYVSCQECMRVYDVHTCK 352 African clawed frog
P21551       323 -----GCELLCCGRGYRT--K--TQRVTERCHCTFHWCCHVSCLNCTNTQVLHECL 369 axolotl
XP_003252539 365 -----GCELLCCGRGHRT--R--TQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL 411 White-cheeked Gibbon
P21552       303 -----SCEVMCCGRGYDT--S--HVTRMTKCECKFHWCCAVRCQDCLEALDVHTCK 349 house mouse
NP_001037315 346 -----GCDLMCCGRGYKT--N--TMFVVERCNCTFHWCCEVKCKLCRTEKVVHTCL 392 domestic silkworm
NP_001081637 285 qwerrSCKRLCTDCGLRV--EekKTEIISSCNCKFHWCCTVKCEQCKQVVIKHFCa 338 African clawed frog
NP_493668    326 -----DCSLLCCGRGYEK--K--VQIVEEKCNCKFIYCCEVRCEPCQKRIEKYLCL 372 nematode
NP_571034    282 kwekrTCKRLCGDCGLAVeeR--RAETVSSCNCKFHWCCAVKCEQCRKTVTKYYCv 335 zebrafish
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