2V95,1C5G,1OVA,3FGQ,1ATT,1QLP,2VDX,1QMN,1BY7,2OL2,2CEO,2ZV6,1JMJ,1XU8,2R9Y,1IMV,1K9O,2OAY,2WXW


Conserved Protein Domain Family
SERPIN

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smart00093: SERPIN 
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SERine Proteinase INhibitors
Statistics
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PSSM-Id: 214513
Aligned: 123 rows
Threshold Bit Score: 287.155
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2V95_A     18 FNLYQRLVAlNPD-K-NTLISPVSISMALAMVSLG---SAQTQSLQSLGFNLTE------TSEAEIHQSFQYLNYLLKQS 86  Norway rat
BAA09051   62 YDLYRLRSSaSPT-G-NVLLSPLSVATALSALSLGaehRTESVIHRALYYDLIT------NP--DIHSTYKELLASVTAP 131 house mouse
NP_776565  61 YDLYRVRSGeSPT-A-NVLLSPLSVATALSALSLGaeqRTESNIHRALYYDLIS------NP--DIHGTYKDLLASVTAP 130 cattle
AAA60058   63 YDLYRVRSSmSPT-T-NVLLSPLSVATALSALSLGadeRTESIIHRALYYDLIS------SP--DIHGTYKELLDTVTAP 132 human
NP_777095  92 tDLFSLVAQsSTR-P-NLILSPLSVALALSHLALGaqnQTLQRLKEVLHAD----------SGPCLPHLLSRLCQDLGPG 159 cattle
NP_000053 151 LKLYHAFSAmKKV-EtNMAFSPFSIASLLTQVLLGageNTKTNLESILSYPKDF------T---CVHQALKGFTTKGV-- 218 human
NP_777246 125 LRLYQDFSVlKKR-EtNFIFSPFSIASLLTQILLGaggETRVSLEHLLSYPQNF---------SCVHHALRAFMSEG--- 191 cattle
P20757    106 FHVYKTLSEtWSVaS-GLVFSPVALFSTLTSFYTGaldPTASRLQAFLGVPGEGqgctsrLDGRKVLSSLQTIQGLLVAP 184 sheep
1IMV_A     43 YDLYRVRSSmSPT-T-NVLLSPLSVATALSALSLGadeRTESIIHRALYYDL--------ISSPDIHGTYKELLDTVTAP 112 human
2OAY_A     41 LKLYHAFSAmKKV-EtNMAFSPFSIASLLTQVLLGageNTKTNLESILSYPKDF------T---CVHQALKGFTTKGV-- 108 human
2V95_A     87 DTG-----LEMNMGNAMFLLQKLKLKDSFLADVKQYYE-SEALAIDFEDwTK-ASQQINQHVKDKTQGKIEHVFSDLDSP 159 Norway rat
BAA09051  132 --E-----KNLKSASRIVFERKLRVKSSFVAPLEKSYG-T--RPRILTGnPRvDLQEINNWVQAQMKGKIARSTREMPSA 201 house mouse
NP_776565 131 --Q-----KNLKSASRIIFERKLRIKASFIPPLEKSYG-T--RPRILTGnSRvDLQEINNWVQAQMKGKVARSTREMPSE 200 cattle
AAA60058  133 --Q-----KNLKSASRIVFEKKLRIKSSFVAPLEKSYG-T--RPRVLTGnPRlDLQEINNWVQAQMKGKLARSTKEIPDE 202 human
NP_777095 160 A---------FRLAARMYLQKGFPIKEDFLEQSEQLFG-A--KPMSLTGmKGeDLANINRWVKEATEGKIEDFLSDLPDD 227 cattle
NP_000053 219 -----------TSVSQIFHSPDLAIRDTFVNASRTLYS-S--SPRVLSNnSDaNLELINTWVAKNTNNKISRLLDSLPSD 284 human
NP_777246 192 ----------FTSFSQIFHSSDLTIKDTFAEASQRLYG-SSPRP--LGNdSTaSLELINDWVAKKTNLRIRRLLDSLPED 258 cattle
P20757    185 GGAssqarLLLSTVVGLFTAPGLHLKQPFVQGLSSFAPiTLPRSLDLSTdPNlAAEKINRFMHSATGWNMGRPLAAASPD 264 sheep
1IMV_A    113 --Q-----KNLKSASRIVFEKKLRIKSSFVAPLEKSYG-T--RPRVLTGnPRlDLQEINNWVQAQMKGKLARSTKEIPDE 182 human
2OAY_A    109 -----------TSVSQIFHSPDLAIRDTFVNASRTLYS-SSPR--VLSNnSDaNLELINTWVAKNTNNKISRLLDSLPSD 174 human
2V95_A    160 ASFILVNYIFLRGIWELPFS-PENTREEDFYVNETSTVKVPMMVQSGsiG-YFRDSVFPCQLIQMDYVGNGTAFFILPD- 236 Norway rat
BAA09051  202 LSILLLGVAYFKGQWVTKFD-SRKTTLQDFHLDEDRTVRVPMMSDPKaiLrYGLDSDLNCKIAQLPLTGSMSIIFFLPL- 279 house mouse
NP_776565 201 ISIFLLGVAYFKGQWVTKFD-SRKTSLEDFYLDEERTVKVPMMSDPQavLrYGLDSDLNCKIAQLPLTGSTSIIFFLPQ- 278 cattle
AAA60058  203 ISILLLGVAHFKGQWVTKFD-SRKTSLEDFYLDEERTVRVPMMSDPKavLrYGLDSDLSCKIAQLPLTGSMSIIFFLPL- 280 human
NP_777095 228 TVLLLLNAIHFQGFWRSKFD-PNLTQRGAFHLDEQFTVPVDMMQALTypLhWFLLEQPEIQVAHFPFKNNMSFVVLMPTr 306 cattle
NP_000053 285 TRLVLLNAIYLSAKWKTTFD-PKKTRMEPFHF-KNSVIKVPMMNSKKypVaHFIDQTLKAKVGQLQLSHNLSLVILVPQn 362 human
NP_777246 259 TRLILLNAVALSAKWKIAFD-KGRTSTKPFHL-KSSAIKVPMMNSKKypVaSFTDRTLNRPGGRLQLSHNLSFVILVPQt 336 cattle
P20757    265 STLLFNAYVHFQGKMKGFSLlPGLTE---FWVDNTTSVPVPMLSGSGt-FhYWSDNQNHLSMTRVPLSANGYLLLIQPH- 339 sheep
1IMV_A    183 ISILLLGVAHFKGQWVTKFD-SRKTSLEDFYLDEERTVRVPMMSDPKavLrYGLDSDLSCKIAQLPLTGSMSIIFFLPL- 260 human
2OAY_A    175 TRLVLLNAIYLSAKWKTTFD-PKKTRMEPFHF-KNSVIKVPMMNSKKypVaHFIDQTLKAKVGQLQLSHNLSLVILVPQn 252 human
2V95_A    237 -QG--QMDTVIAALSRDTIDRWGKLMTPR---QVNLYIPKFSMSDTYDLKDVLEDLNIKDLLTNQSDFSGNTKDVPLTLT 310 Norway rat
BAA09051  280 -AVtqNLTMIEESLTSEFIHDIDRELKTI---QAVLTVPKLKLSFEGELTKSLQDMKLQSLFES-PDFSKITG-KPVKLT 353 house mouse
NP_776565 279 -KVtqNLTLIEESLTSEFIHDIDRELKTV---QAVLTIPKLKLSYEGELTKSVQELKLQSLFD-APDFSKITG-KPIKLT 352 cattle
AAA60058  281 -KVtqNLTLIEESLTSEFIHDIDRELKTV---QAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITG-KPIKLT 354 human
NP_777095 307 fEW--NASQVLANLTWDILHQP--SLSER---PTKVQLPKLHLKYQLDLVATLSQLGLQELFQ-APDLRGISDER-LVVS 377 cattle
NP_000053 363 lKH--RLEDMEQALSPSVFKAIMEKLEMSkfqPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNLCGLTEDPDLQVS 439 human
NP_777246 337 vKH--HLQDLEQALSTAVFKAVIKKLEMTkfhPTHLTMPRIKVQSSQDM------LDYFD-FIYDVNLCGLTEDPDVQVS 407 cattle
P20757    340 -HTl-DLRKVEALIFQHNFLTRMKNLSPR---AIHLTVPQLTLKASYDLQDLLAQAKLPTLLGAEANLGKIS-DANLRVG 413 sheep
1IMV_A    261 -KVtqNLTLIEESLTSEFIHDIDRELKTV---QAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITG-KPIKLT 334 human
2OAY_A    253 lKH--RLEDMEQALSPSVFKAIMEKLEMSkfqPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNLCGLTEDPDLQVS 329 human
2V95_A    311 -MVHKAMLQLDEGNVLPNSTNGAPLHLRSEP--LDIKFNKPFILLLFDKFTWSSLMMSQVVNP 370 Norway rat
BAA09051  354 qVEHRAAFEWNEEGAGSSPSPGLQPVRLTFP--LDYHLNQPFLFVLRDTDTGALLFIGRILDP 414 house mouse
NP_776565 353 qVEHRVGFEWNEDGAGTNSSPGVQPARLTFP--LDYHLNQPFIFVLRDTDTGALLFIGKILDP 413 cattle
AAA60058  355 qVEHRAGFEWNEDGAGTTPSPGLQ--PAHLTfpLDYHLNQPFIFVLRDTDTGALLFIGKILDP 415 human
NP_777095 378 sVQHQSALELSEAGVQAAAATSTAMSRMSLSs---FIVNRPFLFFILEDSTSLPLFVGSVRNP 437 cattle
NP_000053 440 aMQHQTVLELTETGVE----AAAASAISVARtlLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498 human
NP_777246 408 gIRHQATLELTESGVDATAASVVSVARn----lLLFEVQQPFLFLLWDQQHKFPVFMGRVYDP 466 cattle
P20757    414 kVLNSVLFELKADGEQAPESVPQPAGPEAL----EVTLNSPFLLAVLERSSGALHFLGRVSRP 472 sheep
1IMV_A    335 qVEHRAGFEWNEDGAGTTPSPGLQPAHLTFP--LDYHLNQPFIFVLRDTDTGALLFIGKILDP 395 human
2OAY_A    330 aMQHQTVLELTETGVEAAAASAISVART--L--LVFEVQQPFLFMLWDQQHKFPVFMGRVYDP 388 human
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