3KTM


Conserved Protein Domain Family
A4_EXTRA

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smart00006: A4_EXTRA 
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amyloid A4
amyloid A4 precursor of Alzheimers disease
Statistics
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Aligned: 6 rows
Threshold Bit Score: 302.115
Threshold Setting Gi: 194911940
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3KTM_A         8 GNAGLLAEPQIAMFCGRLNMHMNVQn---GKWDSDPSGTKT---CIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNW 81   human
ACD99694     270 GNAGLLAEPQIAMFCGRLNMHMNVQn---GKWDSDPSGTKT---CIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNW 343  synthetic cons...
EDL83314      42 GTGFAVAEPQIAMFCGKLNMHVNIQt---GKWEPDPTGTKS---CLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSW 115  Norway rat
AAB96331      46 GAPEAPGSAQVAGLCGRLTLHRDLRt---GRWEPDPQRSRR---CLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERW 119  human
XP_001982404  26 QAASPRWEPQIAVLCEAGQIYQPQYlseeGRWVTDLSKKTTgptCLRDKMDLLDYCKKAYPNRDITNIVESSHYQKIGGW 105  Drosophila erecta
AAA98722      28 SKRHEKFIPMVAFSCGYRNQYMTEE----GSWKTDDERYAT---CFSGKLDILKYCRKAYPSMNITNIVEYSHEVSISDW 100  Caenorhabditis...
3KTM_A        82 CKRGRK---QCKTHpHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEK------STNLHDY 152  human
ACD99694     344 CKRGRK---QCKTHpHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEK------STNLHDY 414  synthetic cons...
EDL83314     116 CRRDKK---QCRS--HIVIPFKCLVGEFVSDVLLVPENCQFFHQERMEVCEKHQRWHTVVKEACLTE------GMTLYSY 184  Norway rat
AAB96331     120 CGGSRSg--SCAHPhHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQ------GLILHGS 191  human
XP_001982404 106 CRQGALnaaKCKGShRWIKPFRCLEGPFQSDALLVPEGCLFDHIHNASRCWPFVRWNQTGAAACQER------GMQMRSF 179  Drosophila erecta
AAA98722     101 CREEGS---PCKWT-HSVRPYHCIDGEFHSEALQVPHDCQFSHVNSRDQCNDYQHWKDEAGKQCKTKkskgnkDMIVRSF 176  Caenorhabditis...
3KTM_A       153 GMLLPCGIDKFRGVEFVCCP 172  human
ACD99694     415 GMLLPCGIDKFRGVEFVCCP 434  synthetic construct
EDL83314     185 GMLLPCGVDQFHGTEYVCCP 204  Norway rat
AAB96331     192 GMLLPCGSDRFRGVEYVCCP 211  human
XP_001982404 180 AMLLPCGISVFSGVEFVCCP 199  Drosophila erecta
AAA98722     177 AVLEPCALDMFTGVEFVCCP 196  Caenorhabditis elegans
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