7Y19


Conserved Protein Domain Family
VpsR
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pfam20161: VpsR (This model is not part of the current CDD release)
VpsR domain
VpsR appears superficially to be a response regulator, based on extension of its alignment to response regulators AlgB and NrtC all the way to the N-terminus. Instead of being a response regulator with a histidine kinase partner, the sigma-54-dependent transcription factor VpsR directly binds to cyclic-di-GMP. Its regulon includes genes for the biosynthesis of the biofilm matrix component called Vibrio polysaccharide (VPS).
Links
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Statistics
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PSSM-Id: 523847
Aligned: 26 rows
Threshold Bit Score: 125.466
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7Y19_A         3 TQFKXDSVPGSLVVVG--GTYEPWLSV--LEQVGWKCHQCADLRKVDAL-LEDIGPCIGIVDLSHDE--FSLNGIANLVS 75  Vibrio vulnific...
WP_065969008  15 FRVGPGAEPRTLLVYC--AAKTLPFREsdITSQGWTLTRVGAWGAARSH-MDRLGAGVGIVCLQD----TSEKAVADAEA 87  Acidiferrobacte...
WP_014002338   7 PRAQSTAVARSLLYVGprAIIASSLAE--LESAGWGMSFAAHIDDAPGA-LSKIRPAAAVIGFDEKDllTSGQKIESIIA 83  Acidithiobacill...
WP_124149092  43 VARIAVGLARTLLYLAr-TPDPDLSAY--LKNRGWELATARTVHEASRL-VKPSSACAGLVDLTG----FAPSDYAGLEA 114 Paraburkholderi...
WP_071040360   3 RLCKAATRTAQVLVVSr-HEDYSIEAS--QFGAGWDIRHVHQLRELERI-VRASTPMAGVIDLEAD---YSDAEYMLLEQ 75  Cupriavidus sp....
WP_103704935   3 TLSASLPAERAVLYVSs-NPDSRIVEL--LTKAAWQVVLVPTDTETARVtIAKAAPRVGLIELPHN---ATPEQLSALQK 76  Paraburkholderi...
WP_090536956   3 TICTSDVASRVALCVLp-SGDERIVRF--LEEAGWQVAHTTSIAEAEHL-LDCCGISVGLVEIPKD---CAPRHLRALES 75  Paraburkholderi...
2_pfamImport   2 HQANVKKVNKKVVILS--SSNDSWVLL--LERNNYDVVRCKDIRELDAI-LEDETNCICIADLTNCV--FSLACITTKAM 74 
Q6LK67         6 TQSKNKSINGRLVAIG--CNYEPWIAL--LEQSGWKTHCCYDLRTADAI-LEEYSPCICIVDLSNND--FSLNSISLRAN 78  Photobacterium ...
WP_087820438   3 AINDKKKTGGRLVAMG--CTYEPWIAL--LEQAGWKTQCCYDLRTADAI-LEEYSPCVCIVDLSNND--FSLNSISQRAN 75  Photobacterium ...

7Y19_A        76 ----THKHVRWLAFIREQQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIG 122 Vibrio vulnificus CMCP6
WP_065969008  88 llgyGHNRFRWIAILDLAFLKSAVANHLISECCLDFHVVPVDVPRLLHSLG 138 Acidiferrobacter thiooxydans
WP_014002338  84 ----HHPHLRWIALLPRKALEDTSIRKLIGSAFYDYHTQPINTARLLVILG 130 Acidithiobacillus caldus
WP_124149092 115 v--lRLQQVGWIALTDSARLACSEVRRMIRHFCFDYVHLPVANATLDYLVS 163 Paraburkholderia dinghuensis
WP_071040360  76 s--lQHPQVAWVAITNSRMLDDERVRRLIRDYCIDYVRTPFSFDNLLYTLK 124 Cupriavidus sp. USMAA2-4
WP_103704935  77 c--lRRAKITWIVLVQPGQSDAAATRQFILDHCYDFITSPYPEPSLLFAIG 125 Paraburkholderia eburnea
WP_090536956  76 c--mERTHTTWIAAVWPGQTDDESLRRFILDYCFDFVTMPCVDERLTFALG 124 Paraburkholderia sartisoli
2_pfamImport  75 ----NNQHVRWVTILNKEQLDVDVVRSFIGKFCSDYFLSPIVDGQFMPFIK 121
Q6LK67        79 ----KTKQVRWIALIKKEQLETDVICQFINNYCVDYFSMPIPSTLLLDTVG 125 Photobacterium profundum
WP_087820438  76 ----KTKQVKWIAIIKKEQLKIDSICQFINNFCVDFFSTPIPSSQLLDTAG 122 Photobacterium aquimaris
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