Conserved Protein Domain Family
DUF6423
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pfam19987: DUF6423 (This model is not part of the current CDD release)
Family of unknown function (DUF6423)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001503) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the amycolamycin A biosynthetic gene cluster from Amycolatopsis sp..
Links
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Statistics
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PSSM-Id: 523805
Aligned: 7 rows
Threshold Bit Score: 229.692
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
SDX62483      22 LAGVADVRRRVLMISGAIDTTGHDVSVCVNLPEPGRWQIIKSETNLTEQTWVAMQVVTDEESTFVNdeDT--LVLSRQFS 99 
WP_364016848   1 MVGTADLARRVLMVTGAIDTTDHDVSVSVSLPEAGRWQVIKAETNLTDQTWVAMQAVMDEESTFVD--DA--MLMSPQFA 76  Amycolatopsis m...
1_pfamImport   1 MAGVADVRRRVLMISGAIDTVDHDVSVTVNLPEPGRWQIIKSETNLTDRTWVAMQAATDEDSVFVDdeDT--LVMSRQFT 78 
WP_094863994   1 MGAVADVRRRVLMVSGAIDAVDHDVSISLHLPEPGRWQVIKSETNLTDQTWVAMQVTADEDTHFVDdgDA--MILSRQFA 78  Amycolatopsis a...
WP_008591938   8 TTAAIDEKRRIVMLTGAIDASGYVINMRTPLPSAGEWTVVKAETNLSNHTWATWQMVLGENVSVAMdgDSpeLLMSRNFE 87  Salimicrobium j...
WP_103374301   8 MVAAIDEQNRMVMITGGIDVNDITIVMRTELPSAGTWTIMKAETNLTDKTWYGWQVTLGSDITVPMagNKpqLLTSRNFE 87  Sulfobacillus s...
WP_231949562  22 MAAVADVRRRVLMISGAVDAIDHDVSMSLHLPEPGRWQVIKSETNLTDQTWTAMQVTTDEDTYFVDggDA--MIMSRQFA 99  Alloactinosynne...

SDX62483     100 KSFMTPDQRRLTFYDGE-VRPGEAVLKVYTLETGSRRPTYSY-SRYSPISTDTAEQSEQTLQGLITDGMGERPVVEVIVP 177
WP_364016848  77 KSFMTPDQRRLTFFDGE-VRPGETVLKTYSMETGGRKPTYFY-SRYSPIATDSAEKSRQTLDELVADGMRQRPVIELIVP 154 Amycolatopsis m...
1_pfamImport  79 KSLITPDQRRLTFYGGE-VRPGEAVVKMYSLETTGRKPTYAY-SRYSPVATDSPEAAAATLDKLVAEGLPQRPVIEIIVP 156
WP_094863994  79 KTFITPDQRRLTFYEGE-VRPGEAVLKVFELETTARRPAYMH-ARYSPLPADSAETSAGKLDRLVTDGMPQRPVLETIVP 156 Amycolatopsis a...
WP_008591938  88 NVRYIPEKNVVVYYGGKpVRPGETVLKFFKVHTKVPEILTAHpARIAP---DNPDYDDVITGVQTNQHLPK---MEIVPV 161 Salimicrobium j...
WP_103374301  88 HARYVPETNTVGFYGGE-IRPGEPILKFYTIETRVPRIVMGH-NRII----DEADAELMAEGQLLGVGLPK---LEIAVP 158 Sulfobacillus s...
WP_231949562 100 RTFLTPDLRRLTYHDGE-VRPGEAVLKVFELECSTRKPTYAH-ARYSAAPTDTPEQIAAAVEQMVADGMPTRPVIEMIIP 177 Alloactinosynne...

SDX62483     178 VTIIG 182
WP_364016848 155 VTVIG 159 Amycolatopsis mediterranei
1_pfamImport 157 VTVIG 161
WP_094863994 157 VTIIG 161 Amycolatopsis antarctica
WP_008591938 162 VQNVN 166 Salimicrobium jeotgali
WP_103374301 159 TKKIA 163 Sulfobacillus sp. hq2
WP_231949562 178 VTVIG 182 Alloactinosynnema sp. L-07
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