Conserved Protein Domain Family
EACC1
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pfam19953: EACC1 (This model is not part of the current CDD release)
Effector Associated Constant Component 1
Effector Associated Constant Component 1 (EACC1) is a component of a membrane-associated two-gene conflict system, a class of NTP-dependent biological conflict systems. It is found either a standalone domain or fused to EAD1 or EAD2. It is comprised of a single conserved TM helix with short, N- and C-terminal extensions. Predicted to insert into the membrane and protrude beyond both the outer and inner layers of the bilayer.
Links
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Statistics
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PSSM-Id: 523801
Aligned: 97 rows
Threshold Bit Score: 47.6669
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_103887626  10 AGRrgsaEDDLRS-LLRWLREDENLAGRADGRVrdgtPPQ-PG-RM-GT-AFDILQLVIGSGLSAAALVVSVLQWRDAR- 83  Actinacidiphila...
WP_093782548   8 ESDe--dVPALHD-FFRWLKDDQDGPEEVRLGTa--aAER-PG-AM-G--ALEVIQVVLGQSTAAAGLVMQFVSWYRSRg 77  Actinacidiphila...
WP_109494743   8 PDQe--dGQLLADeLHDWLVDDVELHRTAKIRr---vPRDaVG-AM-G--VSDVIEVVVSQGIAALNLALAYASWRTTR- 77  Streptomyces sp...
WP_106127751   9 SAGa--dGPALAS-FCSWLQRTPEVARHGRIRA----MPArDGvTM-N--AVATIGVVISSATGIANVLIAYGNWRRTR- 77  Pseudosporangiu...
WP_143232309   8 DDD----PLALAS-LHRWLSRTPEVTRHGDLREi--aGAR-TD-TMdD--TIAVIALVVSGVSALTDVLGACQAWHGNR- 75  Actinoplanes re...
WP_078974305   8 VGDe---gTEVAA-LQRWLALDPDLRGGAAISYa--eDDT-TD-TM-GA-TLDVVDVVLSNGIGLSGLLVAIAGWRRSRa 77  Embleya scabris...
WP_066927855  19 DGRd--gAEGTAS-LYRWLVADPELRGRAEVSAg--aAPTgQG-EM-GG-ALEVVNVVFGDVIALGNLLVAVAAWRGSR- 89  Streptomyces sp...
WP_073756778   8 HEGs--nRQEADA-LRVWLTQEQMLRGQVRIPVd--sVPL-PG-AM-GQ-PLELVSVLLSNTIALGNLLVAVAAWRQSR- 77  Streptomyces sp...
WP_131815443   8 ADDp--sGRELSS-LRAWLLREPGLRGGMAKVTag-gVTG-PG-HM-GAeGLELINVVLSNAIALGSLIVSIASWRASRp 80  Thermostaphylos...
5_pfamImport   1 QSEd--gDQSLTS-LYRWLAEDPEVTRDASILLva-tPPG-AG-EM-GG-AFEVINAVLTHAIALGGLVVSCAAWRASRt 72 

WP_103887626  84 --HRE--P-A-ITLRR--GGMTVEIPSASEvnAA-VlTRAVELLAAVP 122 Actinacidiphila yanglinensis
WP_093782548  78 dgRGG--A-G-FTFVRasDG--LSVTVRHA--TD---DDVRRILAVLA 114 Actinacidiphila guanduensis
WP_109494743  78 --PAP--P-G-VTVTFa-EG-TITLTD------DsP-EALERVLAALR 110 Streptomyces sp. Act143
WP_106127751  78 --PKApaV-T-VTL----GSVTVTVED--------P-EALEKLTRALS 108 Pseudosporangium ferrugineum
WP_143232309  76 --TRP--PaTtVTI----GDVTVDLSD----------PEVVRKLRELF 105 Actinoplanes regularis
WP_078974305  78 piTGAggP-D-IVVRR--GDVEVVLSE-----AT-E-DDIARAVRALE 114 Embleya scabrispora
WP_066927855  90 ---PR--PpQ-VRIER--DGVSITVQDg------sP-ETVERILKVWG 122 Streptomyces sp. NBRC 110611
WP_073756778  78 --PRQpsV-R-IEV----NGRSFILDT-----SN-P-GELEALARALR 110 Streptomyces sp. CB03234
WP_131815443  81 --RRP----P-VHIET--NGVSVVVHT-----ND-P-EDLRAIVEALT 112 Thermostaphylospora chromogena
5_pfamImport  73 --HAP----V-IRIER--DGVTVTVED-----DS-P-DTVRRVIDALG 104
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