Conserved Protein Domain Family
DUF6399
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pfam19936: DUF6399 
Family of unknown function (DUF6399)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000967) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the calyculin A biosynthetic gene cluster from uncultured Candidatus Entotheonella sp.. This family appears to be predominantly found in proteobacteria and cyanobacteria.
Links
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Statistics
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PSSM-Id: 498413
Aligned: 11 rows
Threshold Bit Score: 195.636
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_007192804 259 MLDDLIPALYLERVAARSTRAEPRHRLRALSAQRLAPLQQlsHPIQ-SLDPQTRHHLEQVAGECADLFQRSSSCVEGRNG 337 Thiocapsa marina
WP_015203604 157 LLGYFLPHFYWLSVIKQTKNPALKEIYTQVSRHYLRHLLE--HPLTsKFSKNEWIHWRSWAEQMSAQFQRSSSAIEGRNG 234 Crinalium epips...
ORU93959     322 VIDALLPVVYWHHQLHKTQNRQLREKYQQAWKSSSAVLRQ--HPLTdALSVCKLQHWLTWAEWMVQHFHRSSSAVEGRNG 399
ORU92833      39 LTSCLLPVVYWHHKMEQSKKPKAKKKCRKAWEQASIEIKV--HPFSeSLSISEMERWLTWAENMVRQFHRSSSAVEGRNG 116
ORU94954     311 LTTVLLPVVYWHHKVEQTKKPKVKEKYRKAWEQATDLFKE--HPLSaTLSESEMQHWLTWADNMVRQFHRSSSAVEGRNG 388
WP_006526961   9 VKHQLLATAYWYQQSQRADNSQLREKYEKAYHNARQTWLV--HPLTlNLTPESQNDWWNWALWMVSKFQRCSSPIEGRNG 86  Gloeocapsa sp. ...
ETW99195     202 MDTLLLPLMYWQEQASHTREPRRKAEILKALKATQAAFEA--HTLTqYLSSDVLEGWKQWAMEHVRAFQRASSAVEGRNG 279
WP_080810995 368 LTVGLLPLCYWQYQSQRTDKPTLKAQYRDAYQRAHNVLKA--HPLTrTLEAEVYRYWYSWASEMVTKFQRTTAAVEGRNG 445 Halomicronema h...
WP_009150015 417 MHEQLIPARYLERVATRQSRAEERDRLEALSERLLAPLRApdHPFQ-QLDAATQATLEQVAGDCADVFQRSSSAVEGRNG 495 Thiorhodovibrio...
WP_007193887 400 VLEQLIPAIYLERVAARSTAAETRHRVQAVSTALLDALRRadHPLQ-RLAPANSARVEQVAGACADLFQRSSSCVEGRNG 478 Thiocapsa marina
WP_100918590 400 LLTQLIPALYLERVANRSTLAEPRHRLHALSRQLLEPLRQrdHPLQ-ALPEAERARLEQVAGDCADLFQRSSSSVEGRNG 478 Candidatus Thio...

WP_007192804 338 FLALYQHGHHRLGPSKQQVLTALHNFAIKRPDGTTAAERFFAQPHPSLFEQVLERMPWPARPARRRPR 405 Thiocapsa marina
WP_015203604 235 YLSRLHHCGRGISSAQLRVLTVIHNFDIQRADKTTAAQRLFNQEFPALFDWVISQMGDLPLPRKSYQI 302 Crinalium epipsammum
ORU93959     400 SLSKMYHNGRGISESRLKALTVIHNYGLKRRDGTTAAQRFFEQDSPDLFSWILDEMGELPLPRQARPK 467
ORU92833     117 CLSQMYHNGRGLSEKRLKALTVIHNYGIKREDGTTAATRLFDIEFPGLFSWLLDEMGELPLPRKGRER 184
ORU94954     389 CLSQMYHNGRGLSEKRLKALTVIHNYEIKRENGTTAAMRLFGTNFPDLFSWLLNEMGELPLPRKERGV 456
WP_006526961  87 YLSQIHHNRRGLSSQRLKVATVIHNYVIRRSDGTTAAERLFCLKFPDLFEFLVHHLGELPQPRRARKS 154 Gloeocapsa sp. PCC 73106
ETW99195     280 YLSQMQHNHRGLPKRRYQVWSALHNFDCHAADGSTPASRFFRHEFPDLFETVLAQIDELPRPRERRQV 347
WP_080810995 446 YLGQIHHSRRRLSDRQLQVMSVIHNFDLKRLDGSTAAQRLFKQPHPDLFQTVLAQMHDLPLPRQRAKA 513 Halomicronema hongdechloris
WP_009150015 496 QLSLFHHGRHRLSERKLSALTAIHNFHIRRSDETTAAERLFGCAHPSLFEEVLKRTPLPPPARRRRAR 563 Thiorhodovibrio frisius
WP_007193887 479 QLSLHHHGRHRLSDRRLAALTAVHNFHIRRPDSTTAAERFFGRTHPALFEQLILRVPLPPRPRRRRPR 546 Thiocapsa marina
WP_100918590 479 QLSLHHHGRHRLSDRKLEALTAVHNFHLRRPDGTTAAERFFGRAHETLFAQVLQRMPLPPPPARRRPR 546 Candidatus Thiodictyon synt...
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