Conserved Protein Domain Family
DUF6387
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pfam19924: DUF6387 
Family of unknown function (DUF6387)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001055) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the yersiniabactin biosynthetic gene cluster from Escherichia coli. This family appears to be predominantly found in proteobacteria.
Links
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Statistics
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PSSM-Id: 498401
Aligned: 21 rows
Threshold Bit Score: 110.679
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_105051626   1 MSPLTKKIAIpKWFNLTNYSELNNLSLKQVYSELTVRINmISQLYDEYESinifPISKKW------KNIIAGTPI----- 69  Psychrosphaera ...
WP_078745442   1 MEVTKKNIDL-SWYKHSNYEYLESCSLYELYQQLSARAL-LRDMLPTENE----WVLSHWeqikqtGKISLSDMGyqidi 74  Oceanospirillum...
Q6D6P9         7 KAEIVE--ALsEWFDVSRYAVLKDLTLEQIYAELERRIF----AYKARQQwetaGEENQLlaihhdALIRSGKVIretkw 80  Pectobacterium ...
Q12SG5         4 MEIISSTAQLpTWYTPERYIHLKRASYDVILNELWLRHH-ANEDIEQGKEckelSLLFNKrfindl-------------- 68  Shewanella deni...
WP_118960283   8 IDCVRRLKRLaKWYRPNRYAWVKDASLSKISDELSSRRVaYHELKNNSFEdgyiGDLFS---------ITLEELPakeps 78  Colwellia sp. R...
Q6FAG9         8 RKLIKNTDDLpKVFDINKYNDMDKLSAFEWFFLIQSRFL-LHDILENGLSnwigTNKLTDteeqeaMTLIVASHLekpls 86  Acinetobacter b...
WP_090238028   1 MAKIDRVEDLpEWFDLEKYKGAESFGVTEWIYHLRNRWH-LFDSFDELKKqgitVESFPGs----dHWLPGNLERfrsdp 75  Pseudomonas gui...
WP_147275200   8 LTTLKAKDDLpPWFKSKHY--YQGLEEERWLDEIVMRLS-VQTVLENTDDi----------------------------- 55  Thioalbus denit...
WP_047885273   8 SIRNTNHDDWpSWFNIRNYDQLNSITIGEFLNELDYRLT-LHERIPQYCRgrfrENG--WtqitrgNPIVSSCPTitras 84  Photobacterium ...
Q8EJS5        10 RIKTSDHPKWpNWFSIKNYDCLADLTAAQFLNELEFRLT-LHNS-PTLPNgrklTDSKRWqliqngYVIINSNPVtqp-- 85  Shewanella onei...

WP_105051626  70 -----------------------SESAITqslnTptAIASQLTNVDIEMCYETLQMAMEEpkfiiantsffkdkytrelc 126 Psychrosphaera ...
WP_078745442  75 a-----------------ttketPRTALVspiyV--SQVEEMAEAVIRAKETMLFLAEQAqqeindkyd----------- 124 Oceanospirillum...
Q6D6P9        81 l-----------------sdshmLAHS---------YAVRPMTRTSLFNYGRAMYRLENNvpkd---------------- 118 Pectobacterium ...
Q12SG5        69 -----------------dippddAYNALGlnvkLisSPVLKILAGEVMrdcdatdnry---------------------- 109 Shewanella deni...
WP_118960283  79 n-----------------iecerIHEELYk------SDVYPVSMGHILLCEKKYKTRSDYdadpfsqk------------ 123 Colwellia sp. R...
Q6FAG9        87 ldlfvkykkdnneiidleisssdHYNFMYkhlpVneLYEDEFESIQLMIKNSGIKLKYTG-------------------- 146 Acinetobacter b...
WP_090238028  76 l-----------------rveegLSDVLH-------PPVRDMAFGDLAGQRYFEDHAACQdeysaddv------------ 119 Pseudomonas gui...
WP_147275200  56 ------------------------------------PHAKELFDSLVVNENYTKGALASSlgdisdlwgvkep------- 92  Thioalbus denit...
WP_047885273  85 -------------------------------lpletNSVHVMKRIDLETLTMMKDANDARrpplpspa------------ 121 Photobacterium ...
Q8EJS5        86 ----------------------------------dfPTVIALNHVDLLGITEEIKLRSGddyldlepq------------ 119 Shewanella onei...

WP_105051626 127 sdcldilknnvneehswkhnekqeslftkysdKHPNVTFEEFKSLYELiydnpeieyeeciplsllcd--tcqtlslkqk 204 Psychrosphaera ...
WP_078745442 125 -----------------------iidsfgderIREKSLSADTKNFRDGglddtymllkeraslpkyd----idhmaydva 177 Oceanospirillum...
Q6D6P9       119 -----------------------------dvsLSSEYISEYLKQGGLN-------------------------------- 137 Pectobacterium ...
Q12SG5           --------------------------------------------------------------------------------     Shewanella deni...
WP_118960283     --------------------------------------------------------------------------------     Colwellia sp. R...
Q6FAG9           --------------------------------------------------------------------------------     Acinetobacter b...
WP_090238028 120 ------------------------eywqfmaaCDEPVREGLAASVGLMkarmsp-------------------------- 149 Pseudomonas gui...
WP_147275200  93 --------------------sgfdalylaaviSSSPQGSNLFSELNTFrqsqtpgklftelpetlkaqkrksfgelidwk 152 Thioalbus denit...
WP_047885273 122 ------------------------effngkvpSPDATREITQKeelernra----------------------------- 148 Photobacterium ...
Q8EJS5           --------------------------------------------------------------------------------     Shewanella onei...

WP_105051626 205 iaepypnpiiPDRSFNNEeftVDYSHsdtlgysllkfypqfhT----ATEILAAIKPMVESICKK-HISTQISStkleqn 279 Psychrosphaera ...
WP_078745442 178 llnscsgvckGRTEVHLS---IDLAA----------------T----NKEILRDVKAFLEKYREIiGIYPPEPK------ 228 Oceanospirillum...
Q6D6P9       138 ----------PANKMLIE---IDLDEa---------------S----SDDLAEHLKVLISEWQKHlKAPKPPEKdfr-fg 184 Pectobacterium ...
Q12SG5       110 vheigmcnlfGDGFVSLN---LKLA-----------------T----NSEIIDEFTILLDKLRKEsNIPEPKREfr---s 162 Shewanella deni...
WP_118960283 124 --ntmqfladSDEDIWVN---LPLYM----------------R----DSDILDEVQKLLNQLRAKlNKPQPDNYk----m 174 Colwellia sp. R...
Q6FAG9       147 ----------EDKPFSPV---MDILKshfkfhvkqydypitiNpyypDHVIFGEFKKILAQIREKlGFNEKNKSl----s 209 Acinetobacter b...
WP_090238028 150 ----------------gfplmVDLRA----------------T----DSVLITAFSRWLKNERAK--QPASTSSkr---e 188 Pseudomonas gui...
WP_147275200 153 sepinpseviSGFPLV-----VDLEQd--------------------DETLKIAFEVWLAGARAEsGEAKNPYS------ 201 Thioalbus denit...
WP_047885273 149 --eyqmpfnaSRDSVLLS---IDLENa---------------N----DQQILKDIAYLLPQLREKlRCPEKSSDdkkhdn 204 Photobacterium ...
Q8EJS5       120 --qlmplqgqSRDLTVVG---IDLTK----------------P----NKAILGDCEFLINQLRKTlSIPEPKVPdnfqan 174 Shewanella onei...

WP_105051626 280 KSFVKGIFDYQIIPYLDLYLWRV-----------------------YFS------AKESVLIsdtsvKNNDEPISLllgd 330 Psychrosphaera ...
WP_078745442 229 NLTIEKVINDRVIPYIDLTIWDSleghgilt-------dalaaqilFSFnngvkeVRSADKV-----QRVTAPNAE---- 292 Oceanospirillum...
Q6D6P9       185 HKTFQRILDYKIIPLMDLIGWEQlnnqkipy--------pvlagllHPDir---yARGSEQI-----KDTDYPLSY---- 244 Pectobacterium ...
Q12SG5       163 VEKFDAIFQNHVFEYIDLTLWAKannlkipp----------rvfaeaiVnadktpAFTATEIqnkvqRNAQQILSI---- 228 Shewanella deni...
WP_118960283 175 KSRIERLKRGGIFEYLDLDIWAKangyllnlstiaqainshtvdtdLYSsgsekkVYDKRTVsddikRQAEIAITL---- 250 Colwellia sp. R...
Q6FAG9       210 KKDLLNWASYKLLPYMDLKILELaenikitnai-------------icsvlykkgEYGEDTL-----RKSVEPIRR---- 267 Acinetobacter b...
WP_090238028 189 LPAYNDWAGFGLLPYLDLTLWEGetgnkltln---------------imaqavgyFRGGDSF-----RKTVPSLAAkl-- 246 Pseudomonas gui...
WP_147275200 202 TRDYATWRDYGVLQAFDLQFWARlnkarftnnv------------isnaiwpldeVDTTERL-----RKVTNPKIKeift 264 Thioalbus denit...
WP_047885273 205 LQTLKKIIEYKAIAFLDLDFYFLthpnnqlaplk--psasllsrilFDG------EKDEYQV-----KRTIRPYYA---- 267 Photobacterium ...
Q8EJS5       175 EKTFKKLLTYKLIPYLDLMMYCYnhipfyednwqkl------eftqnvlselllgEESKQELrmelyKKTYAPFYR---- 244 Shewanella onei...

WP_105051626 331 efdekhlpkykiddlnialnsgerdlgnhfktkilpKYLSIKNVTAS---SL 379 Psychrosphaera saromensis
WP_078745442 293 ------------------------------------KALSETFLNKL---YA 305 Oceanospirillum multiglobuliferum
Q6D6P9       245 ------------------------------------EFLNNDNYFKS---LN 257 Pectobacterium atrosepticum
Q12SG5       229 ------------------------------------SYLKQLEVDIK---TH 241 Shewanella denitrificans OS217
WP_118960283 251 ------------------------------------KFSDKLDLILA---NQ 263 Colwellia sp. RSH04
Q6FAG9       268 ------------------------------------KILDQMVFDGAddvTE 283 Acinetobacter baylyi
WP_090238028 247 -----------------------------------mHSLNELECLGV---IE 260 Pseudomonas guineae
WP_147275200 265 d------------------------------wtmarRLWRQVELSKA---LA 283 Thioalbus denitrificans
WP_047885273 268 ------------------------------------NTVLNTELMNR---LF 280 Photobacterium ganghwense
Q8EJS5       245 ------------------------------------KILSNESHLMQ---LL 257 Shewanella oneidensis
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