Conserved Protein Domain Family
DUF6297
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pfam19814: DUF6297 
Family of unknown function (DUF6297)
This family of bacterial proteins is functionally uncharacterized. Proteins in this family are typically between 139 and 579 amino acids in length. There is a conserved sequence motif GPV. Some members of this family are hypothetical ABC transporter permeases.
Links
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Statistics
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PSSM-Id: 498302
Aligned: 37 rows
Threshold Bit Score: 132.412
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_098460540  107 CASSRLLLPTAVLLGNYAVVLGLARL---FGPVLVSAAEGSWLLDAPLDRRRLL-SGRLVVPLVAAFLFPGLITGLVAGL 182 Propionicimona...
WP_157728271   79 CVDARLVLPLPLGAAVLALA---VRTlvaLGPLVASRASGTFLLGTPVDRRGLLlRPA-AALLAGATVLGAALVSVLVLL 154 Actinopolymorp...
WP_073489857   65 GQTHAAGGAWLLVAGLVLLLAGALRVlgaLGPVSAGRPMLTWVLSTPVDRRGLL-STRFSAGALGSAVPGAALFTAVALT 143 Streptoallotei...
WP_043717712   64 TPHTAATVSWMAVAIAVAAVAAFGQAllaVGPIWAGSATQTWILASPVDRRSAL-LPTYVRTLLIAGVGGALLAGGLTAI 142 Kutzneria sp. 744
WP_088969837   69 APGDPGERYWIAVAAALAATGLAWRLlraAGPLLVTPAAQSWLFSAPVDRAALL-LPRAAALAGTTALGAGLLGLGAAVA 147 Micromonospora...
WP_091445296   73 DPADPAERYWLAGAALLAVAGLGWQGlraLGPVLVTPATQAWAVSAPVDRRAWL-LPRAGLLIGLAAGAGALLGAALGAV 151 Micromonospora...
jgi:Kfla_2656  73 CGWLLDTVPWILIPLLVS---GMLRIllsVGPVSASRATGFWLLATPVDRGALL-RPTYRLVIVAAAIVGALSAVLGFAL 148
WP_118397917   67 CLETRALLPWLVALTGVLLVVVAARM---FGPLFVSPAVSSWLLPTWADRAALL-RPRLLRSALLAVALGAAVALGGASL 142 Aeromicrobium ...
WP_056908680   71 CVEVRAAAPWLASLALALLALGLARL---LGPVFSPPAANAWLLSTPVDRGSLL-RPGWWRTAALAAGGAGLALIAPAAL 146 Nocardioides
WP_108344412   68 CAVTRELAPWLSALAVAAVVLGVARL---LGPVFSPPAANVWLLGTPVDRGALL-RPGWLRTVAFTVVGVVAVLLTPAVL 143 Nocardioides c...

WP_098460540  183 TGM--DWPAVGIWTLAAAAGSAALVAFSAAQQASE--RSRLL--MLLQNLTGAAALAVIALVVAVAADKVPAEALSGid- 255 Propionicimona...
WP_157728271  155 TSS--HPVAVGAGALAGAGVGVVAVAASILAQGAP--KVRRAl-GIACDVVVVATLAAVPLLLLDRAVWSTAWAQ----- 224 Actinopolymorp...
WP_073489857  144 DHL--PVALVAWSAVLGALVGVAMYAAMVLLEAGG--QAERVsrRGSAALAGVAVLLALIPVSAPLTGWRPDVPPA---- 215 Streptoallotei...
WP_043717712  143 YPP--WLVNLLSNGISGFLAAVILVAVTIEAQTRA--RA-----VPFAVLLGVAVVMGGVVALQLDVPSL---------- 203 Kutzneria sp. 744
WP_088969837  148 GGPd-RPIDLLWSALAGAACGTLAVAGAVVAQAAP--RDPRWarLVDRVLLGSAGAVALLVVAGHLLDRPVPPLS----- 219 Micromonospora...
WP_091445296  152 GTAlvDRADLGLAALAGAACGAAGVGLSIVAQGSL--PGRRWprLLGTGATVAGALGAVTVVVAHFTGLGLVRPS----- 224 Micromonospora...
jgi:Kfla_2656 149 FGA--AWSTVGEAALLTLLLLICTACATVWAQQAAprTRWAL--RIADLLLVVAAIPALILASRAGAGVSSSELVGTetl 224
WP_118397917  143 GGF--SGSAIVLLTLSAGLAGLATLCFAASSQTRE--DSGA---RLLTWALAAVIWLGLMVLALGRGRVTSPPD------ 209 Aeromicrobium ...
WP_056908680  147 GGL--SGSAAVLFVVAGAAASLACVGVAALSQVRE--DAMA---RRLSWTVAGALWVGLGLAATDDLGSLPTLP------ 213 Nocardioides
WP_108344412  144 GGF--TPSTGVAFVVAGSAASLACVALAALSQVHE--HAAA---RWLTWLVTGSLWVLLAATADGRLDGVPSVP------ 210 Nocardioides c...

WP_098460540  256 -aaR------------WVFLGVAVAALAAGTFWLILALR-RLDQLRRTRLASGGALVSGMQGAMFALDFGLIRDILVERR 321 Propionicimona...
WP_157728271  225 ---P------------APLVACAVVAAVAAVALVVTVVH-RVGRLPRRELVAGGELLSGLAGAAASLDTSMVSDLLVARR 288 Actinopolymorp...
WP_073489857  216 ---E------------PLLYVGVPLVAVVAAAVLVSAHR-ALGRLSRGVLGAGGDLTMVTVTSVAWMDLSLLTGTLEFRR 279 Streptoallotei...
WP_043717712  204 ---A------------VSMDLVPRVLALPALLAVRVGWV-ALRRLHRGALSAGTDLVQAAAVSSVWLDLSLVSSALMLRR 267 Kutzneria sp. 744
WP_088969837  220 ---L------------ALTAAVAVVGVPVAGWAVRWAYR-ALGGVDRASLISGGQFAGAATSAAVLLDPSMIEDLVQSRR 283 Micromonospora...
WP_091445296  225 ---V------------PVAGLVVVVALPLAVLTGALALR-ALPRVDRASLTTGAQFANAAATAAVLLDPSLLFGLVESRR 288 Micromonospora...
jgi:Kfla_2656 225 imyTngdqaggptgdqLRLLVTAALVVLIAGVLVSFTAR-SLDRLPRQSVVAGGELLAGMAGAAITMDISLLADVVAGRH 303
WP_118397917  210 ---G------------SLAWIVGVVAGGLAVVLLLARVVrRLGTVRRVHLLAGGALAPSLSGALAGLDLALAYDVLLARR 274 Aeromicrobium ...
WP_056908680  214 ---A------------AVGMALAVLVVLAALALFWVARR-AVGTVTRRVLGYTENLSPSLSGALSSVDLGLMYDVLLARR 277 Nocardioides
WP_108344412  211 ---T------------PVALALTAAGLVAGAVLAWRVRG-SLSSMSRRVLGQTENLSPALSGALSSLDLGLMYDVLLARR 274 Nocardioides c...

WP_098460540  322 AAAIGHVRPTRGR-GLGLTALIWRDAERLRRNPKMFIGLAVSLFVPYAVDALRLSQLNPLISGLALVAAMIPFLGSLRVL 400 Propionicimona...
WP_157728271  289 FRQRGAGRTLRGH-GSGLVGVAVREAQRSLRSPQRLALAVGLLAVPYAVDRVGVPTLTPLLAVVVGYLALRPLGGGLHVV 367 Actinopolymorp...
WP_073489857  280 LRRIATVRSRRGG-GRGVSVLLWSELRRLVRMPGAVAGWVALALVPYAAKVVVSSTWVLPLQLVAGALAVSRLTAGLRAI 358 Streptoallotei...
WP_043717712  268 ARRIGRVRSVRLR-GSRAFAFVLADVARLRRYPATIAVWVALLPVPFFAAVSLPPIAVGPVQLLFAYAAADRFAGGLRTI 346 Kutzneria sp. 744
WP_088969837  284 WRAIGRVPGRPLRrGGRFAVLVRAEARRLRRHPSALPVWAALLLAMYAAAVALPASA-GSWQVVLGYLAVDRLTGGLRTI 362 Micromonospora...
WP_091445296  289 WRGVGRVRSRRFLaGRRWWVLLQAEARRLRRHPSAPTAWVALVLLQYAVAVAVPVAA-GTAQVVGAFLAAGRLAGGLRAV 367 Micromonospora...
jgi:Kfla_2656 304 WRMVGRLRSRRGR-GARVQALIHREFLRVLRWPRRLVVGFGLLVVPYAVAGTGYDVLVPIAAGIAGFIATRPLMDGLRSV 382
WP_118397917  275 WRNHPPVRSRRGG-PAGAKALVWLDLVRVTRSPHSLLLLAAAVVIPYVAETADLGDAVLLVASLTGFVAGLGLCSSLRVV 353 Aeromicrobium ...
WP_056908680  278 WGRGAHVRTHTGG-PLGWWALVHRDLLRARRAPQPFVLLAGLLLVPYAAAEAGAGRAVVLATTLAGLLGGPALCAGLRVV 356 Nocardioides
WP_108344412  275 WGKGATVTSRRGG-PVGWWALVHSDLRRAVRAPQPFVVLAGMTLVPYAAASADAGRALVLATTLAGLLAGPPLCAGLRVV 353 Nocardioides c...

WP_098460540  401 SRTGGLARGLPFKTASLRTASMAVPAAVALLWALAAVPAFVGVAGTg-ADRSLEDGLIAALITGAAGLLGGVRWVTAKRV 479 Propionicimona...
WP_157728271  368 ARSAGLRRAFPVADRPLRLAFAAPLLAAAVLWALAALPAVAGNSMLvfGFSAPEPAAVTWLALAATIAAGGIRSVTRQRV 447 Actinopolymorp...
WP_073489857  359 NGRTGLRRMLPFGDRALRLLHCVVPVVAALVWAGATVPAVvv-----aLDADRATAAFLLLAVAATAGAGAMRSAIRPPL 433 Streptoallotei...
WP_043717712  347 SGSPALRRSLGGTDGELKAIHLTLPAVGAVVWCALTSFAL------------PLAPSVTTVISAAGAVVVVYAMATRKPM 414 Kutzneria sp. 744
WP_088969837  363 SRSAGLRRTLGGSDTELRLAHVVLPAVGALVWYAATLPVV------------RPTVGPVDGLLLAGIVAAAYRSATRPPM 430 Micromonospora...
WP_091445296  368 SRSPGLRRVLGGDDTAVRLVHLVWPAVGAALWWVVTLPVG------------GAQPGWLTVVLVLGVVAGAYRAATKPPM 435 Micromonospora...
jgi:Kfla_2656 383 CRSTGLVRALGMELRELRVAMGVVPAGFVLLWSAVAFPALGDL--------------PTTFAVGAGVLTGVVRQASAPPP 448
WP_118397917  354 GRTPGLARMLPFPDATTRAATIVVPSAAMIAYGLATGPALHGATGA-----SWAVTWYLALAVGGSSTAAAVRWVTGRPP 428 Aeromicrobium ...
WP_056908680  357 VRTRSLARMMPFRRQSILLAHLVVPGSALMLFAVATTGTLLPL-------TDTGSAVNLAIACGLSSIAATVRWVTGKPP 429 Nocardioides
WP_108344412  354 VRTRGVARMLPMSTAQVRGAHLVMPGTALLLYALGTTWTLLPL-------MPTQEAVRLAIACGLSSLAATLRWVSARPP 426 Nocardioides c...

WP_098460540  480 DFGAP 484 Propionicimonas paludicola
WP_157728271  448 SYDGP 452 Actinopolymorpha singaporensis
WP_073489857  434 VYDVP 438 Streptoalloteichus hindustanus
WP_043717712  415 DYGGG 419 Kutzneria sp. 744
WP_088969837  431 RYDGP 435 Micromonospora siamensis
WP_091445296  436 SYDTA 440 Micromonospora yangpuensis
jgi:Kfla_2656 449 SYSGP 453
WP_118397917  429 DYSRP 433 Aeromicrobium sp. A1-2
WP_056908680  430 NYAAP 434 Nocardioides
WP_108344412  427 DYGKP 431 Nocardioides currus
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