Conserved Protein Domain Family
DUF6283
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pfam19800: DUF6283 
Family of unknown function (DUF6283)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001735) is described by MIBiG as an example of the following biosynthetic class, other (unspecified), in particular the pentostatine biosynthetic gene cluster from Streptomyces antibioticus. This family appears to be predominantly found in bacteria.
Links
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Statistics
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PSSM-Id: 498289
Aligned: 22 rows
Threshold Bit Score: 112.43
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
PQM19520       7 PPAPRPCAFCPYGTDVPSGVWGGVEYARLPLYDRPTyd----qPARLFSCHVHALgdaraRVCGGWAGCHD-GdHLLALR 81 
WP_111026601   7 KPRPRPCASCPFRRDVPSGVWAADEYDKLTRYDGPTye----qSPRVFMCHQGRRn----EVCSGWLGHTDePwEMLAVR 78  Curtobacterium ...
YP_009003282   6 HALPAPCKSCPYRKDVPSAIWAEEEYEKLPMFDGEIveqvingGTQLFLCHQRNN-----ALCSGWLGCHG-PeNLLALR 79 
WP_011798007  28 GYRRKPCGGCPWLVQN-AGAFPAEAFRHSASTAYDM-------ARNVFSCHESGik--paHTCAGFLLRGAg--HNMAVR 95  Polaromonas nap...
WP_239126810   9 GPASSPCPACPYRRDVPSGVWSRHEYVRLTAYDLDTal----qPSTVLVCYGSEPr----RVCAGWAGCHD-TrELLALR 79  Asanoa
WP_370321522  24 SPAARPCGTCPYRRDCPSGIWTGETYGRLVLYDLPTal----qPNRVFLCHLQDTat-grRVCGGWAGTHD-TeQLLGLR 97  Actinoplanes sp...
KQP63185       3 APAKNPCGTCPYRTDVPAGVWHPEEYAKLPPFDRDTas----qPPGLFLCHQQDQ-----RVCAGWAGCHD-MeESLGVR 72 
WP_014985660  20 PPAPRPCSSCPYRRDVPSGIWHADEYAKLRNYDQDMae----qPPGLFQCHQTDAhsdlrRLCAGWAGCH--GdNLLALR 93  Nocardia brasil...
YP_009303228   7 VPAPRPCASCPYRRDVPSGIWDASEYSKLTAYDRDTha----qPLGLFLCHQTNGddpnaRLCAGWVGCH--GdQLIALR 80 
WP_211328836  10 APARRPCATCPYRRDVPSGVWAPEEYEKLRRYDAPTme----qPPGVFVCHTTGRnaetaRVCAGWAGTHD-GpHLLALR 84  Thermomonospora...

PQM19520      82 LAVVAGQITVETAeairDYscpVELFPSGAEAAVHGVREISCPGPEGRR 130
WP_111026601  79 IGVLDGSLDPSCA----EYtttVPLFPSGTAAAEHGKREMLSPGADAAR 123 Curtobacterium sp. MCBD17_040
YP_009003282  80 LH--GNEVEPEVF----DYqtdVPLFSSGAEAAAHGMKDMAKPSEAAER 122
WP_011798007  96 IGYITGRYKDDVAga------dAALHDSYRAMAVANGVAHDDPVLAPCR 138 Polaromonas naphthalenivorans
WP_239126810  80 LAAPWGTMAADDLaathRYvspAPLFSSGREAAVHGAASLADPSPAARA 128 Asanoa
WP_370321522  98 YAVIDGDMTAETLqailVYrspVPLFESGKAAYEHGIRDINNPSPEAQA 146 Actinoplanes sp. ATCC 53533
KQP63185      73 VAALTG-VAEDVIeavlDYvspVPLFASGEEAARHGMSGVEEPPDPARK 120
WP_014985660  94 LALIQQRISAGTFeaaiNYqspTPLFSSGAEAADHGQADIHRPSPDAVN 142 Nocardia brasiliensis
YP_009303228  81 LAVARGRLPGEVF----DYttdVPLFESGAAAAAHGVAGIDNPDARAVN 125
WP_211328836  85 IAAMTGTLSGEDVhatiDHvspDPLFASGAEAADHGMSEVNAPGPRALV 133 Thermomonospora umbrina
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